EA200800397A1 - Композиции тизанидина и способы лечения с применением композиций - Google Patents

Композиции тизанидина и способы лечения с применением композиций

Info

Publication number
EA200800397A1
EA200800397A1 EA200800397A EA200800397A EA200800397A1 EA 200800397 A1 EA200800397 A1 EA 200800397A1 EA 200800397 A EA200800397 A EA 200800397A EA 200800397 A EA200800397 A EA 200800397A EA 200800397 A1 EA200800397 A1 EA 200800397A1
Authority
EA
Eurasian Patent Office
Prior art keywords
compositions
tizanidine
treatment methods
patient
composition
Prior art date
Application number
EA200800397A
Other languages
English (en)
Inventor
Моше Флашнер-Барак
Алон Гавин Юдельман
Original Assignee
Тева Фармасьютикал Индастриес Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Тева Фармасьютикал Индастриес Лтд. filed Critical Тева Фармасьютикал Индастриес Лтд.
Publication of EA200800397A1 publication Critical patent/EA200800397A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Изобретение относится к способам лечения мышечной спастичности у больного с неврологическим заболеванием, включающим введение больному, который нуждается в таком лечении, состава тизанидина, обеспечивающего концентрацию тизанидина в крови по меньшей мере приблизительно 900 пг/мл в течение примерно пяти часов, причем состав вводят перед сном.
EA200800397A 2005-08-01 2006-08-01 Композиции тизанидина и способы лечения с применением композиций EA200800397A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70473105P 2005-08-01 2005-08-01
US81907406P 2006-07-06 2006-07-06
PCT/US2006/030273 WO2007016676A1 (en) 2005-08-01 2006-08-01 Tizanidine compositions and methods of treatment using the compositions

Publications (1)

Publication Number Publication Date
EA200800397A1 true EA200800397A1 (ru) 2008-08-29

Family

ID=37440863

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200800397A EA200800397A1 (ru) 2005-08-01 2006-08-01 Композиции тизанидина и способы лечения с применением композиций

Country Status (11)

Country Link
US (1) US20070078174A1 (ru)
EP (1) EP1909787A1 (ru)
JP (1) JP2008540688A (ru)
KR (1) KR20080028480A (ru)
AU (1) AU2006275405A1 (ru)
BR (1) BRPI0614907A2 (ru)
CA (1) CA2612480A1 (ru)
EA (1) EA200800397A1 (ru)
IL (1) IL186325A0 (ru)
MX (1) MX2008001520A (ru)
WO (1) WO2007016676A1 (ru)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080194655A1 (en) * 2007-02-09 2008-08-14 Scott Bull Zero order controlled release compositions of tizanidine
US8524749B2 (en) * 2007-02-09 2013-09-03 Alza Corporation Controlled release compositions of tizanidine
KR101490253B1 (ko) * 2007-08-10 2015-02-05 엘지전자 주식회사 무선 통신 시스템에서의 제어정보 전송 및 수신 방법
TR200708925A1 (tr) 2007-12-26 2009-07-21 Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ Kontrollü salım sağlayan flurbiprofen ve kas gevşetici kombinasyonları
WO2009146310A1 (en) * 2008-05-28 2009-12-03 Concert Pharmaceuticals Inc. Deuterated tizanidine
US20100298305A1 (en) * 2008-11-26 2010-11-25 The United States Government, As Represented By The Department Of Veterans Affairs Tizanidine for the treatment of post-traumatic stress disorder and nightmares
WO2010065547A1 (en) * 2008-12-01 2010-06-10 Map Pharmaceuticals, Inc. Inhalation delivery methods and devices
CN101780075B (zh) * 2009-01-16 2013-10-30 四川科瑞德制药有限公司 一种治疗失眠的联合用药物
CA2761538A1 (en) * 2009-05-20 2010-12-23 Lingual Consegna Pty Ltd Buccal and/or sublingual therapeutic formulation
KR102431738B1 (ko) * 2014-12-25 2022-08-10 주식회사 다이셀 초고속 붕해 정제 및 그 제조 방법
US20220193043A1 (en) 2019-03-29 2022-06-23 Cipla Limited Pharmaceutical Combination Formulations Comprising Tizanidine, Resveratrol and Piperine
CN115400123A (zh) * 2021-05-26 2022-11-29 四川科瑞德制药股份有限公司 一种替扎尼定液体制剂及其用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776493A (en) * 1989-07-14 1998-07-07 Alza Corporation Oral osmotic device for delivery of nystatin with hydrogel driving member
US5200194A (en) * 1991-12-18 1993-04-06 Alza Corporation Oral osmotic device
AU666509B2 (en) * 1991-12-24 1996-02-15 Yamanouchi Pharmaceutical Co., Ltd. Intrabuccally disintegrating preparation and production thereof
US5576014A (en) * 1994-01-31 1996-11-19 Yamanouchi Pharmaceutical Co., Ltd Intrabuccally dissolving compressed moldings and production process thereof
US5817335A (en) * 1995-05-26 1998-10-06 Alza Corporation Osmotic device with high drug loading and delayed activation of drug delivery
IL127956A0 (en) * 1996-07-11 1999-11-30 Farmarc Nederland Bv Inclusion complex containing indole selective serotonin agonist
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
CA2448558A1 (en) * 2001-07-10 2003-01-23 Teva Pharmaceutical Industries, Ltd. Drug delivery system for zero order, zero order-biphasic, ascending or descending drug delivery
US6455557B1 (en) * 2001-11-28 2002-09-24 Elan Pharmaceuticals, Inc. Method of reducing somnolence in patients treated with tizanidine
MXPA05005038A (es) * 2002-11-12 2005-07-01 Teva Pharma Composiciones farmaceuticas y formas de dosis para la entrega bucal y sublingual de tizanidina y metodos para administrar tizanidina sublingual o bucalmente.
WO2005046648A1 (en) * 2003-11-12 2005-05-26 Glenmark Pharmaceuticals Ltd. Extended release pharmaceutical dosage forms comprising alpha-2 agonist tizanidine

Also Published As

Publication number Publication date
JP2008540688A (ja) 2008-11-20
AU2006275405A1 (en) 2007-02-08
MX2008001520A (es) 2008-04-07
KR20080028480A (ko) 2008-03-31
WO2007016676A1 (en) 2007-02-08
EP1909787A1 (en) 2008-04-16
CA2612480A1 (en) 2007-02-08
IL186325A0 (en) 2008-02-09
US20070078174A1 (en) 2007-04-05
BRPI0614907A2 (pt) 2011-04-19

Similar Documents

Publication Publication Date Title
EA200800397A1 (ru) Композиции тизанидина и способы лечения с применением композиций
LTPA2017009I1 (lt) Brutono tirozinkinazės inhibitoriai
BRPI0417959A (pt) anticorpo ou fragmento funcional deste, composição farmcêutica, método para tratamento ou profilaxia de acidente vascular cerebral e outras doenças/distúrbios neurológicos em um ser humano, uso de um anticorpo anti-nogo, e, métodos para inibir a neurodegeneração e/ou promover a recuperação funcional em um paciente humano, para promover o crescimento axonal, para produzir um anticorpo anti-nogo e para produzir uma composição farmacêutica intravenosamente administrável
UA99094C2 (ru) Способ лечения пациента с системной красной волчанкой
MXPA05011110A (es) Composiciones inmunogenicas novedosas para la prevencion y tratamiento de un padecimiento originado por meningococos.
CY1116463T1 (el) Θεραπεια συνδυασμου για τη θεραπευτικη αγωγη διαταραχων ανεπαρκειας πρωτεϊνης
TW200630105A (en) Herbal composition PHY906 and its use in chemotherapy
CY1111478T1 (el) Ενδειξη δοσολογιας προγεστερονης στην αντιμετωπιση τραυματικης εγκεφαλικης βλαβης
MX2009006760A (es) Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedades meningococicas.
MX349481B (es) Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
ATE399553T1 (de) Pharmazeutische zusammensetzungen mit dextromethorphan und chinidin zur behandlung von neurologischen erkrankungen
NO20074999L (no) Metode og preparat for behandling av perifere vaskulaere sykdommer
IS8432A (is) Mótefni sem bindast viðtaka hvítfrumuboða-4
TW200501983A (en) Uses of anti-insulin-like growth factor I receptor antibodies
BR0011823A (pt) Derivado de benzimidazol, composto, composição farmacêutica, uso de um derivado de benzimidazol, e, método para tratamento, prevenção ou alìvio de uma doença ou de um distúrbio ou de uma condição de um corpo animal vivo
EA200500782A1 (ru) Лечение геморрагического шока
EA201070121A1 (ru) Лекарственная форма, содержащая слитый белок glp-1-fc
WO2006138608A3 (en) Pharmaceutical compositions and use thereof
EA200870254A1 (ru) Способ лечения воспалительных заболеваний
EA200501710A1 (ru) Замещённые карбоновые кислоты
WO2007002836A3 (en) Methods and compositions for the prevention and treatment of kidney disease
DE60218193D1 (de) Verwendung von 2-oxo-1-pyrrolidin-derivaten zur herstellung eines arzneimittels zur behandlung von dyskinesia
EP1543158A4 (en) REGULATED APTAMER THERAPEUTICS
BR0310061A (pt) Métodos para o tratamento de doenças e condições respiratórias com um inibidor seletivo da inos e um inibidor da pde e suas composições
BRPI0410761A (pt) uso de leucina, e, composição para administração entérica a pacientes