EA200601390A1 - COMPOSITIONS OF MODAFINILLA - Google Patents

COMPOSITIONS OF MODAFINILLA

Info

Publication number
EA200601390A1
EA200601390A1 EA200601390A EA200601390A EA200601390A1 EA 200601390 A1 EA200601390 A1 EA 200601390A1 EA 200601390 A EA200601390 A EA 200601390A EA 200601390 A EA200601390 A EA 200601390A EA 200601390 A1 EA200601390 A1 EA 200601390A1
Authority
EA
Eurasian Patent Office
Prior art keywords
modafinilla
compositions
enantiomerically
narcolepsy
polymorphs
Prior art date
Application number
EA200601390A
Other languages
Russian (ru)
Other versions
EA009949B1 (en
Inventor
Хики Магали Бургхол
Мэттью Петерсон
Орн Алмарссон
Марк Оливейра
Original Assignee
Сефалон, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2004/029013 external-priority patent/WO2005023198A2/en
Application filed by Сефалон, Инк. filed Critical Сефалон, Инк.
Publication of EA200601390A1 publication Critical patent/EA200601390A1/en
Publication of EA009949B1 publication Critical patent/EA009949B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Abstract

Получают и обсуждают полиморфы и сольваты рацемического, энантиомерно чистого и энантиомерно смешанного модафинила. Кроме того, указанные формы описаны как пригодные для лечения многих заболеваний, включающих в себя, но не ограничивающихся перечисленным, нарколепсию.The polymorphs and solvates of racemic, enantiomerically pure and enantiomerically mixed modafinil are prepared and discussed. In addition, these forms are described as suitable for the treatment of many diseases, including, but not limited to, narcolepsy.

EA200601390A 2004-02-06 2005-02-01 Modafinil compositions EA009949B1 (en)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US54275204P 2004-02-06 2004-02-06
US56041104P 2004-04-06 2004-04-06
US57341204P 2004-05-21 2004-05-21
US57917604P 2004-06-12 2004-06-12
US58199204P 2004-06-22 2004-06-22
US58675204P 2004-07-09 2004-07-09
US58823604P 2004-07-15 2004-07-15
PCT/US2004/029013 WO2005023198A2 (en) 2003-09-04 2004-09-04 Modafinil compositions
US63178604P 2004-11-30 2004-11-30
PCT/US2005/002782 WO2005077894A1 (en) 2004-02-06 2005-02-01 Modafinil compositions

Publications (2)

Publication Number Publication Date
EA200601390A1 true EA200601390A1 (en) 2006-12-29
EA009949B1 EA009949B1 (en) 2008-04-28

Family

ID=38456572

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200601390A EA009949B1 (en) 2004-02-06 2005-02-01 Modafinil compositions

Country Status (7)

Country Link
EP (1) EP1718607A4 (en)
JP (1) JP4917441B2 (en)
AU (1) AU2005212229B2 (en)
CA (1) CA2556106A1 (en)
EA (1) EA009949B1 (en)
IL (1) IL176934A (en)
WO (1) WO2005077894A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4906233B2 (en) 2002-03-01 2012-03-28 ユニバーシティー オブ サウス フロリダ Multi-component solid phase containing at least one active pharmaceutical ingredient
AU2003243699B2 (en) 2002-06-21 2009-01-15 Transform Pharmaceuticals, Inc. Pharmaceutical compositions with improved dissolution
FR2849029B1 (en) 2002-12-20 2005-03-18 Lafon Labor PROCESS FOR THE PREPARATION AND CRYSTALLINE FORMS OF OPTICAL ENANTIOMERS OF MODAFINIL.
US8183290B2 (en) 2002-12-30 2012-05-22 Mcneil-Ppc, Inc. Pharmaceutically acceptable propylene glycol solvate of naproxen
WO2005099822A2 (en) * 2004-04-13 2005-10-27 Cephalon, Inc. Reduction of drug / drug interactions with modafinil
EP1828098A1 (en) * 2005-11-22 2007-09-05 Teva Pharmaceutical Industries Ltd Crystal forms of cinacalcet hci and processes for their preparation
CN100343228C (en) * 2006-02-17 2007-10-17 中国科学院上海有机化学研究所 Selective prepn process of single antimer of 2-dibenzylsulfenyl-acetamide with higher antimer
JP2009508880A (en) * 2006-02-21 2009-03-05 テバ ファーマシューティカル インダストリーズ リミティド Novel crystal form of armodafinil and its preparation method
EP2155664A2 (en) * 2007-06-04 2010-02-24 Generics Ýuk¨Limited Novel process
WO2009025791A2 (en) 2007-08-16 2009-02-26 Teva Pharmaceutical Industries Ltd. Purification of armodafinil
WO2009045488A2 (en) * 2007-10-02 2009-04-09 Teva Pharmaceutical Industries Ltd. Novel crystalline forms of armodafinil and preparation thereof
WO2009090663A1 (en) * 2008-01-15 2009-07-23 Lupin Limited Novel crystalline polymorph of armodafinil and an improved process for preparation thereof
KR102126389B1 (en) * 2018-09-14 2020-06-25 셀라이온바이오메드 주식회사 A composition for preventing or treating liver diseases comprising benzhydrylthio acetamide derivative as an active ingredient

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2593809B1 (en) * 1986-01-31 1988-07-22 Lafon Labor BENZHYDRYLSULFINYLACETAMIDE, PROCESS FOR PREPARATION AND THERAPEUTIC USE
FR2804322B1 (en) * 2000-01-31 2002-04-19 Lafon Labor USE OF MODAFINIL FOR THE MANUFACTURE OF A MEDICINAL PRODUCT FOR CORRECTING VIGILANCE DISORDERS ASSOCIATED WITH MYOPATHIES
KR20060097771A (en) * 2000-07-27 2006-09-15 테바 파마슈티컬 인더스트리즈 리미티드 Crystalline and pure modafinil, and process of preparing the same
FR2849029B1 (en) * 2002-12-20 2005-03-18 Lafon Labor PROCESS FOR THE PREPARATION AND CRYSTALLINE FORMS OF OPTICAL ENANTIOMERS OF MODAFINIL.

Also Published As

Publication number Publication date
JP4917441B2 (en) 2012-04-18
AU2005212229B2 (en) 2011-06-09
IL176934A0 (en) 2006-12-10
EP1718607A1 (en) 2006-11-08
WO2005077894A1 (en) 2005-08-25
CA2556106A1 (en) 2005-08-25
AU2005212229A1 (en) 2005-08-25
EA009949B1 (en) 2008-04-28
EP1718607A4 (en) 2008-05-28
IL176934A (en) 2013-06-27
JP2007522147A (en) 2007-08-09

Similar Documents

Publication Publication Date Title
EA200601390A1 (en) COMPOSITIONS OF MODAFINILLA
TW200719892A (en) Modulators of indoleamine 2,3-dioxygenase and methods of using the same
EA200700225A1 (en) TETRAPTIDE ANALOGUES
EA200700175A1 (en) COMPOSITIONS AND METHODS OF TREATING INFLAMMATORY DISEASES
EA200800909A1 (en) OBTAINING PREGABALIN AND RELATED COMPOUNDS
EA201101084A1 (en) PHENOXYACIC ACIDS AS PPAR DELTA ACTIVATORS
EA200801560A1 (en) BIFENYL CARBOKSAMIDES
MY163480A (en) Sclerostin binding agents
ZA200702322B (en) Compositions and methods for the diagnosis and treatment of tumor
EA200700489A1 (en) NEW BENZO-CONDENSED HETEROARYL SULFAMIDE DERIVATIVES, USEFUL AS ANTI-CONVOLTIVE AGENT
EA200870019A1 (en) LACTAMIC CONNECTIONS AND METHODS OF THEIR APPLICATION
TW200716584A (en) Dihydrobenzofuran derivatives and uses thereof
EA201070422A1 (en) OXADIAZOL DERIVATIVES
EA200801291A1 (en) CARBONYLAMINOPYRROPYRAZOLES AS AN EFFICIENT KINAZ INHIBITORS
TW200730518A (en) Crystalline forms of docetaxel and processes for their preparation
SG155947A1 (en) Compositions and methods for the diagnosis and treatment of tumor
HK1085140A1 (en) Pharmaceutical compositions and method of using levodopa and carbidopa
WO2005000860A3 (en) Compositions and methods for treatment of disease with acetylated disaccharides
EA200870514A1 (en) ACETYLENE HETEROARRYL COMPOUNDS
MXPA06000407A (en) Cci-779 isomer c.
EA200600588A1 (en) COMPOUNDS CONTAINING Haloalkyl As Inhibitors Of Cystine Proteases
TW200716088A (en) Formulations and methods for treating amyloidosis
TW200734306A (en) Novel compounds, their preparation and use
TW200738649A (en) Calcilytic compounds
DK1641803T3 (en) Thienopyrimidine derivatives as potassium channel inhibitors

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU