EA200601390A1 - COMPOSITIONS OF MODAFINILLA - Google Patents

COMPOSITIONS OF MODAFINILLA

Info

Publication number
EA200601390A1
EA200601390A1 EA200601390A EA200601390A EA200601390A1 EA 200601390 A1 EA200601390 A1 EA 200601390A1 EA 200601390 A EA200601390 A EA 200601390A EA 200601390 A EA200601390 A EA 200601390A EA 200601390 A1 EA200601390 A1 EA 200601390A1
Authority
EA
Eurasian Patent Office
Prior art keywords
modafinilla
compositions
enantiomerically
narcolepsy
polymorphs
Prior art date
Application number
EA200601390A
Other languages
Russian (ru)
Other versions
EA009949B1 (en
Inventor
Хики Магали Бургхол
Мэттью Петерсон
Орн Алмарссон
Марк Оливейра
Original Assignee
Сефалон, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2004/029013 external-priority patent/WO2005023198A2/en
Application filed by Сефалон, Инк. filed Critical Сефалон, Инк.
Publication of EA200601390A1 publication Critical patent/EA200601390A1/en
Publication of EA009949B1 publication Critical patent/EA009949B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Epidemiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Anesthesiology (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Получают и обсуждают полиморфы и сольваты рацемического, энантиомерно чистого и энантиомерно смешанного модафинила. Кроме того, указанные формы описаны как пригодные для лечения многих заболеваний, включающих в себя, но не ограничивающихся перечисленным, нарколепсию.The polymorphs and solvates of racemic, enantiomerically pure and enantiomerically mixed modafinil are prepared and discussed. In addition, these forms are described as suitable for the treatment of many diseases, including, but not limited to, narcolepsy.

EA200601390A 2004-02-06 2005-02-01 Modafinil compositions EA009949B1 (en)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US54275204P 2004-02-06 2004-02-06
US56041104P 2004-04-06 2004-04-06
US57341204P 2004-05-21 2004-05-21
US57917604P 2004-06-12 2004-06-12
US58199204P 2004-06-22 2004-06-22
US58675204P 2004-07-09 2004-07-09
US58823604P 2004-07-15 2004-07-15
PCT/US2004/029013 WO2005023198A2 (en) 2003-09-04 2004-09-04 Modafinil compositions
US63178604P 2004-11-30 2004-11-30
PCT/US2005/002782 WO2005077894A1 (en) 2004-02-06 2005-02-01 Modafinil compositions

Publications (2)

Publication Number Publication Date
EA200601390A1 true EA200601390A1 (en) 2006-12-29
EA009949B1 EA009949B1 (en) 2008-04-28

Family

ID=38456572

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200601390A EA009949B1 (en) 2004-02-06 2005-02-01 Modafinil compositions

Country Status (7)

Country Link
EP (1) EP1718607A4 (en)
JP (1) JP4917441B2 (en)
AU (1) AU2005212229B2 (en)
CA (1) CA2556106A1 (en)
EA (1) EA009949B1 (en)
IL (1) IL176934A (en)
WO (1) WO2005077894A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030224006A1 (en) 2002-03-01 2003-12-04 Zaworotko Michael J. Multiple-component solid phases containing at least one active pharmaceutical ingredient
EP1515703A1 (en) 2002-06-21 2005-03-23 Transform Pharmaceuticals, Inc. Pharmaceutical compositions with improved dissolution
FR2849029B1 (en) 2002-12-20 2005-03-18 Lafon Labor PROCESS FOR THE PREPARATION AND CRYSTALLINE FORMS OF OPTICAL ENANTIOMERS OF MODAFINIL.
US8183290B2 (en) 2002-12-30 2012-05-22 Mcneil-Ppc, Inc. Pharmaceutically acceptable propylene glycol solvate of naproxen
WO2005099822A2 (en) * 2004-04-13 2005-10-27 Cephalon, Inc. Reduction of drug / drug interactions with modafinil
US7563930B2 (en) * 2005-11-22 2009-07-21 Teva Pharmaceutical Industries Ltd Crystal forms of Cinacalcet HCI and processes for their preparation
CN100343228C (en) * 2006-02-17 2007-10-17 中国科学院上海有机化学研究所 Selective prepn process of single antimer of 2-dibenzylsulfenyl-acetamide with higher antimer
JP2009508880A (en) * 2006-02-21 2009-03-05 テバ ファーマシューティカル インダストリーズ リミティド Novel crystal form of armodafinil and its preparation method
EP2155664A2 (en) * 2007-06-04 2010-02-24 Generics Ýuk¨Limited Novel process
US7960586B2 (en) 2007-08-16 2011-06-14 Teva Pharmaceutical Industries Ltd. Purification of armodafinil
US20090105346A1 (en) * 2007-10-02 2009-04-23 Alexandr Jegorov Novel crystalline forms of armodafinil and preparation thereof
WO2009090663A1 (en) * 2008-01-15 2009-07-23 Lupin Limited Novel crystalline polymorph of armodafinil and an improved process for preparation thereof
KR102126389B1 (en) * 2018-09-14 2020-06-25 셀라이온바이오메드 주식회사 A composition for preventing or treating liver diseases comprising benzhydrylthio acetamide derivative as an active ingredient

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2593809B1 (en) * 1986-01-31 1988-07-22 Lafon Labor BENZHYDRYLSULFINYLACETAMIDE, PROCESS FOR PREPARATION AND THERAPEUTIC USE
FR2804322B1 (en) * 2000-01-31 2002-04-19 Lafon Labor USE OF MODAFINIL FOR THE MANUFACTURE OF A MEDICINAL PRODUCT FOR CORRECTING VIGILANCE DISORDERS ASSOCIATED WITH MYOPATHIES
EP1309547B1 (en) * 2000-07-27 2007-01-17 Teva Pharmaceutical Industries Ltd. Crystalline and pure modafinil, and process of preparing the same
FR2849029B1 (en) * 2002-12-20 2005-03-18 Lafon Labor PROCESS FOR THE PREPARATION AND CRYSTALLINE FORMS OF OPTICAL ENANTIOMERS OF MODAFINIL.

Also Published As

Publication number Publication date
AU2005212229B2 (en) 2011-06-09
EP1718607A1 (en) 2006-11-08
IL176934A (en) 2013-06-27
EA009949B1 (en) 2008-04-28
EP1718607A4 (en) 2008-05-28
WO2005077894A1 (en) 2005-08-25
AU2005212229A1 (en) 2005-08-25
JP2007522147A (en) 2007-08-09
CA2556106A1 (en) 2005-08-25
JP4917441B2 (en) 2012-04-18
IL176934A0 (en) 2006-12-10

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU