EA200500967A1 - NEW POWDER INHALATION SYSTEM FOR EXTRACTIVE EXTRACTION - Google Patents

NEW POWDER INHALATION SYSTEM FOR EXTRACTIVE EXTRACTION

Info

Publication number
EA200500967A1
EA200500967A1 EA200500967A EA200500967A EA200500967A1 EA 200500967 A1 EA200500967 A1 EA 200500967A1 EA 200500967 A EA200500967 A EA 200500967A EA 200500967 A EA200500967 A EA 200500967A EA 200500967 A1 EA200500967 A1 EA 200500967A1
Authority
EA
Eurasian Patent Office
Prior art keywords
powder inhalation
inhalation system
fine particles
lyophilized composition
sec
Prior art date
Application number
EA200500967A
Other languages
Russian (ru)
Other versions
EA009775B1 (en
Inventor
Тикамаса Ямасита
Акицуна Акаги
Юитиро Фукунага
Original Assignee
Оцука Фармасьютикал Ко., Лтд
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Оцука Фармасьютикал Ко., Лтд filed Critical Оцука Фармасьютикал Ко., Лтд
Priority claimed from PCT/JP2003/015931 external-priority patent/WO2004054555A1/en
Publication of EA200500967A1 publication Critical patent/EA200500967A1/en
Publication of EA009775B1 publication Critical patent/EA009775B1/en

Links

Abstract

Настоящее изобретение включает новую порошковую ингаляционную систему, пригодную для чрезлегочного введения. Порошковая ингаляционная система по настоящему изобретению, характеризуется использованием сочетания:(1) емкости, вмещающей лиофилизированную композицию, приготовленную посредством лиофилизации жидкой композиции, содержащей ингредиенты в нерастворенной форме, и которая имеет:(i) непорошкообразную форму в виде кека,(ii) индекс дезинтеграции 0,05 или выше и(iii) свойство превращаться в тонкодисперсные частицы со средним диаметром 10 мкм или меньше или фракцию тонкодисперсных частиц в количестве 10% или больше при получении воздушного воздействия со скоростью воздуха по крайней мере 1 м/с и расходом воздуха по крайней мере 17 мл/с; и(2) устройства, содержащего элемент, осуществляющий указанное воздушное воздействие на лиофилизированную композицию в указанной емкости, и элемент для выпуска порошкообразной лиофилизированной композиции, которая превращена в тонкодисперсные частицы.Международная заявка была опубликована вместе с отчетом о международном поиске.The present invention includes a new powder inhalation system suitable for transpulmonary administration. The powder inhalation system of the present invention is characterized by using a combination of: (1) a container containing a lyophilized composition prepared by freeze-drying a liquid composition containing ingredients in undissolved form, and which has: (i) a non-powdery form in the form of a cake, (ii) a disintegration index 0.05 or higher and (iii) the property to turn into fine particles with an average diameter of 10 μm or less, or a fraction of fine particles in an amount of 10% or more when receiving air impact Ia having an air speed of at least 1m / sec and an air flow rate of at least 17 ml / sec; and (2) a device containing an element that performs the specified air exposure on the lyophilized composition in the specified container, and an element for producing a powdered lyophilized composition that has been turned into fine particles. The international application was published together with an international search report.

EA200500967A 2002-12-13 2003-12-12 Novel dry inhalation system for transpulmonary administration EA009775B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002363158 2002-12-13
PCT/JP2003/015931 WO2004054555A1 (en) 2001-06-15 2003-12-12 Novel dry powder inhalation system for transpulmonary administration

Publications (2)

Publication Number Publication Date
EA200500967A1 true EA200500967A1 (en) 2006-02-24
EA009775B1 EA009775B1 (en) 2008-04-28

Family

ID=40490921

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200500967A EA009775B1 (en) 2002-12-13 2003-12-12 Novel dry inhalation system for transpulmonary administration

Country Status (7)

Country Link
JP (1) JP4822709B2 (en)
AR (1) AR042454A1 (en)
CU (1) CU20050115A7 (en)
EA (1) EA009775B1 (en)
MY (1) MY154957A (en)
TW (1) TWI327073B (en)
ZA (1) ZA200505312B (en)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05963A (en) * 1990-04-13 1993-01-08 Toray Ind Inc Polypeptide composition
JP3492154B2 (en) * 1997-06-26 2004-02-03 サンデン株式会社 Beverage vending machine
JP3547612B2 (en) * 1998-03-20 2004-07-28 株式会社日立ユニシアオートモティブ Inhalation type dispenser
GB2353222B (en) * 1999-06-23 2001-09-19 Cambridge Consultants Inhalers
IL149085A0 (en) * 1999-10-29 2002-11-10 Inhale Therapeutic Syst A dry powder composition containing a di or tripeptide
JP4931282B2 (en) * 2000-10-02 2012-05-16 日本ケミカルリサーチ株式会社 Bioactive peptide-containing powder
JP3943845B2 (en) * 2001-02-15 2007-07-11 芳枝 米谷 Liposome vector

Also Published As

Publication number Publication date
TWI327073B (en) 2010-07-11
JPWO2004054555A1 (en) 2006-04-13
TW200418520A (en) 2004-10-01
AR042454A1 (en) 2005-06-22
CU20050115A7 (en) 2009-02-20
JP4822709B2 (en) 2011-11-24
ZA200505312B (en) 2006-10-25
MY154957A (en) 2015-08-28
EA009775B1 (en) 2008-04-28

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU