EA200500140A1 - Лекарство и способ для снижения потребления алкоголя и/или табака - Google Patents
Лекарство и способ для снижения потребления алкоголя и/или табакаInfo
- Publication number
- EA200500140A1 EA200500140A1 EA200500140A EA200500140A EA200500140A1 EA 200500140 A1 EA200500140 A1 EA 200500140A1 EA 200500140 A EA200500140 A EA 200500140A EA 200500140 A EA200500140 A EA 200500140A EA 200500140 A1 EA200500140 A1 EA 200500140A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- pharmacologically acceptable
- galantamine
- administration
- nervous system
- central nervous
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Addiction (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Настоящее изобретение относится к лекарству для лечения хронической зависимости, отличающемуся тем, что оно состоит из сочетания двух форм для введения, одна из которых непрерывно высвобождает по меньшей мере один модулятор никотиновых рецепторов, а другая форма, которая может вводиться независимо от первой формы, обеспечивает быстрое попадание галантамина или одной из его фармакологически приемлемых солей в центральную нервную систему, а также к способу лечения зависимости от определенных веществ путем модулирования нейронных никотиновых рецепторов, осуществляемому в две стадии, на которых постоянное лечение лекарственной формой для введения, непрерывно доставляющей модулятор никотиновых рецепторов, в случае появления острой тяги к определенному веществу дополняют введением галантамина или его фармакологически приемлемой соли при помощи формы для введения, обеспечивающей быстрое попадание галантамина или его фармакологически приемлемой соли в центральную нервную систему.Международная заявка была опубликована вместе с отчетом о международном поиске.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10235556A DE10235556A1 (de) | 2002-08-03 | 2002-08-03 | Medikament und Verfahren zur Verringerung des Alkohol- und/oder Tabakkonsums |
| PCT/EP2003/008236 WO2004014393A1 (de) | 2002-08-03 | 2003-07-25 | Medikament und verfahren zur verringerung des alkohol-und/oder tabakkonsums |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200500140A1 true EA200500140A1 (ru) | 2005-06-30 |
| EA012460B1 EA012460B1 (ru) | 2009-10-30 |
Family
ID=30469388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200500140A EA012460B1 (ru) | 2002-08-03 | 2003-07-25 | Лекарство и способ для снижения потребления алкоголя и/или табака |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20060079500A1 (ru) |
| EP (1) | EP1524982B1 (ru) |
| JP (1) | JP2006501212A (ru) |
| KR (1) | KR100736016B1 (ru) |
| CN (1) | CN1674911A (ru) |
| AR (1) | AR040762A1 (ru) |
| AT (1) | ATE458488T1 (ru) |
| AU (1) | AU2003253327B2 (ru) |
| BR (1) | BR0313423A (ru) |
| CA (1) | CA2495418A1 (ru) |
| DE (2) | DE10235556A1 (ru) |
| EA (1) | EA012460B1 (ru) |
| IL (1) | IL166464A0 (ru) |
| MX (1) | MXPA05001294A (ru) |
| MY (1) | MY142346A (ru) |
| NO (1) | NO20050376L (ru) |
| PL (1) | PL375404A1 (ru) |
| TW (1) | TW200402297A (ru) |
| UA (1) | UA84405C2 (ru) |
| WO (1) | WO2004014393A1 (ru) |
| ZA (1) | ZA200500510B (ru) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10338544B4 (de) * | 2003-08-19 | 2017-08-31 | Janssen Pharmaceutica N.V. | Buccale Formulierungen des Galanthamins und deren Anwendungen |
| US20090253654A1 (en) | 2005-09-22 | 2009-10-08 | Galantos Pharma Gmbh | Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2906265A (en) * | 1957-09-03 | 1959-09-29 | Maryland Devices Inc | Nasal adaptor for valved dispenser |
| US4597961A (en) * | 1985-01-23 | 1986-07-01 | Etscorn Frank T | Transcutaneous application of nicotine |
| DE4010079A1 (de) * | 1990-03-29 | 1991-10-02 | Lohmann Therapie Syst Lts | Pharmazeutische formulierung zur behandlung des alkoholismus |
| US5336675A (en) | 1991-05-14 | 1994-08-09 | Ernir Snorrason | Method of treating mania in humans |
| DE4301783C1 (de) * | 1993-01-23 | 1994-02-03 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit Galanthamin als wirksamem Bestandteil |
| DE4301782C1 (de) * | 1993-01-23 | 1994-08-25 | Lohmann Therapie Syst Lts | Verwendung von Galanthamin zur Behandlung der Nicotinabhängigkeit |
| TW506836B (en) * | 1996-06-14 | 2002-10-21 | Janssen Pharmaceutica Nv | Fast-dissolving galanthamine hydrobromide tablet |
| AU775914B2 (en) * | 1998-12-24 | 2004-08-19 | Janssen Pharmaceutica N.V. | Controlled release galantamine composition |
| US6369058B1 (en) * | 1999-02-04 | 2002-04-09 | New Millennium Pharmaceutical Research Inc. | Brain delivery of folic acid for the prevention of alzheimer's disease and stroke |
| US6264987B1 (en) * | 2000-05-19 | 2001-07-24 | Alkermes Controlled Therapeutics Inc. Ii | Method for preparing microparticles having a selected polymer molecular weight |
| US6306423B1 (en) * | 2000-06-02 | 2001-10-23 | Allergan Sales, Inc. | Neurotoxin implant |
| US20020019421A1 (en) * | 2000-07-05 | 2002-02-14 | Roni Biberman | Compositions and therapy for substance addiction |
| WO2003020289A1 (en) * | 2001-08-30 | 2003-03-13 | Ortho-Mcneil Pharmaceutical, Inc. | Treatment of dementia and memory disorders with anticonvulsants and acetylcholinesterase inhibitors |
-
2002
- 2002-08-03 DE DE10235556A patent/DE10235556A1/de not_active Withdrawn
-
2003
- 2003-07-25 UA UAA200500950A patent/UA84405C2/ru unknown
- 2003-07-25 EP EP03784081A patent/EP1524982B1/de not_active Expired - Lifetime
- 2003-07-25 CN CNA038186381A patent/CN1674911A/zh active Pending
- 2003-07-25 AT AT03784081T patent/ATE458488T1/de not_active IP Right Cessation
- 2003-07-25 US US10/523,012 patent/US20060079500A1/en not_active Abandoned
- 2003-07-25 DE DE50312449T patent/DE50312449D1/de not_active Expired - Fee Related
- 2003-07-25 BR BR0313423-7A patent/BR0313423A/pt not_active IP Right Cessation
- 2003-07-25 MX MXPA05001294A patent/MXPA05001294A/es active IP Right Grant
- 2003-07-25 KR KR1020057001996A patent/KR100736016B1/ko not_active IP Right Cessation
- 2003-07-25 WO PCT/EP2003/008236 patent/WO2004014393A1/de active Application Filing
- 2003-07-25 EA EA200500140A patent/EA012460B1/ru not_active IP Right Cessation
- 2003-07-25 CA CA002495418A patent/CA2495418A1/en not_active Abandoned
- 2003-07-25 PL PL03375404A patent/PL375404A1/xx not_active Application Discontinuation
- 2003-07-25 AU AU2003253327A patent/AU2003253327B2/en not_active Ceased
- 2003-07-25 JP JP2004526790A patent/JP2006501212A/ja active Pending
- 2003-08-01 MY MYPI20032921A patent/MY142346A/en unknown
- 2003-08-01 TW TW092121119A patent/TW200402297A/zh unknown
- 2003-08-01 AR AR20030102773A patent/AR040762A1/es unknown
-
2005
- 2005-01-19 ZA ZA200500510A patent/ZA200500510B/en unknown
- 2005-01-24 IL IL16646405A patent/IL166464A0/xx unknown
- 2005-01-24 NO NO20050376A patent/NO20050376L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR100736016B1 (ko) | 2007-07-06 |
| CA2495418A1 (en) | 2004-02-19 |
| DE50312449D1 (de) | 2010-04-08 |
| KR20050032590A (ko) | 2005-04-07 |
| IL166464A0 (en) | 2006-01-15 |
| EA012460B1 (ru) | 2009-10-30 |
| JP2006501212A (ja) | 2006-01-12 |
| MXPA05001294A (es) | 2005-09-08 |
| PL375404A1 (en) | 2005-11-28 |
| UA84405C2 (ru) | 2008-10-27 |
| TW200402297A (en) | 2004-02-16 |
| DE10235556A1 (de) | 2004-02-19 |
| AR040762A1 (es) | 2005-04-20 |
| EP1524982A1 (de) | 2005-04-27 |
| NO20050376L (no) | 2005-01-24 |
| AU2003253327A1 (en) | 2004-02-25 |
| ZA200500510B (en) | 2005-07-19 |
| US20060079500A1 (en) | 2006-04-13 |
| AU2003253327B2 (en) | 2009-10-08 |
| CN1674911A (zh) | 2005-09-28 |
| ATE458488T1 (de) | 2010-03-15 |
| BR0313423A (pt) | 2005-06-28 |
| WO2004014393A1 (de) | 2004-02-19 |
| MY142346A (en) | 2010-11-15 |
| EP1524982B1 (de) | 2010-02-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ KZ KG MD TJ TM |
|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): BY RU |