EA200400263A1 - Способ получения аморфной формы торсемида - Google Patents
Способ получения аморфной формы торсемидаInfo
- Publication number
- EA200400263A1 EA200400263A1 EA200400263A EA200400263A EA200400263A1 EA 200400263 A1 EA200400263 A1 EA 200400263A1 EA 200400263 A EA200400263 A EA 200400263A EA 200400263 A EA200400263 A EA 200400263A EA 200400263 A1 EA200400263 A1 EA 200400263A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- amorphous form
- tormide
- producing amorphous
- producing
- torsemide
- Prior art date
Links
- NGBFQHCMQULJNZ-UHFFFAOYSA-N Torsemide Chemical compound CC(C)NC(=O)NS(=O)(=O)C1=CN=CC=C1NC1=CC=CC(C)=C1 NGBFQHCMQULJNZ-UHFFFAOYSA-N 0.000 abstract 1
- 238000002441 X-ray diffraction Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229960005461 torasemide Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN830DE2001 IN192178B (https=) | 2001-08-03 | 2001-08-03 | |
| PCT/IB2002/003013 WO2003014086A1 (en) | 2001-08-03 | 2002-08-02 | Process for the preparation of amorphous form of torsemide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA200400263A1 true EA200400263A1 (ru) | 2005-06-30 |
Family
ID=11097098
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200400263A EA200400263A1 (ru) | 2001-08-03 | 2002-08-02 | Способ получения аморфной формы торсемида |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7002018B2 (https=) |
| EP (1) | EP1417172A4 (https=) |
| JP (1) | JP2005519862A (https=) |
| EA (1) | EA200400263A1 (https=) |
| IN (1) | IN192178B (https=) |
| NO (1) | NO20040485L (https=) |
| PL (1) | PL373892A1 (https=) |
| WO (1) | WO2003014086A1 (https=) |
| ZA (1) | ZA200401103B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7980900B2 (en) * | 2004-05-14 | 2011-07-19 | Commscope, Inc. Of North Carolina | Next high frequency improvement by using frequency dependent effective capacitance |
| WO2013132511A1 (en) * | 2012-03-09 | 2013-09-12 | Hetero Research Foundation | Novel polymorph of lurasidone hydrochloride |
| CN103694165B (zh) * | 2013-11-12 | 2016-05-04 | 江苏正大清江制药有限公司 | 吉美嘧啶无定形固化物及制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US34580A (en) * | 1862-03-04 | Improvement in brick-machines | ||
| US30633A (en) * | 1860-11-13 | Improvement in fire-escapes | ||
| GB1477664A (en) | 1974-04-17 | 1977-06-22 | Christiaens Sa A | Pyridine derivatives |
| DE3529529A1 (de) * | 1985-08-17 | 1987-02-19 | Boehringer Mannheim Gmbh | Verfahren zur herstellung einer stabilen modifikation von torasemid |
| HRP980532B1 (en) * | 1998-10-02 | 2005-06-30 | Pliva | Novel crystalline torasemide modification |
| US5914336A (en) * | 1998-06-02 | 1999-06-22 | Boehringer Mannheim Gmbh | Method of controlling the serum solubility of orally administered torasemide and composition relating thereto |
| US6166045A (en) * | 1998-06-02 | 2000-12-26 | Roche Diagnostics Gmbh | Torasemide of modification III |
| JP2003527319A (ja) | 1999-08-11 | 2003-09-16 | テバ ファーマシューティカル インダストリーズ リミティド | トルセミド多形体 |
| HRP20000162B1 (en) | 2000-03-20 | 2004-06-30 | Pliva D D | Amorphous torasemide modification |
| HRP20000328A2 (en) | 2000-05-19 | 2002-02-28 | Pliva Farmaceutska Ind Dionik | Novel polymorph v of torasemide |
-
2001
- 2001-08-03 IN IN830DE2001 patent/IN192178B/en unknown
-
2002
- 2002-08-02 US US10/485,590 patent/US7002018B2/en not_active Expired - Fee Related
- 2002-08-02 PL PL02373892A patent/PL373892A1/xx not_active Application Discontinuation
- 2002-08-02 EP EP02755413A patent/EP1417172A4/en not_active Withdrawn
- 2002-08-02 EA EA200400263A patent/EA200400263A1/ru unknown
- 2002-08-02 WO PCT/IB2002/003013 patent/WO2003014086A1/en not_active Ceased
- 2002-08-02 JP JP2003519036A patent/JP2005519862A/ja not_active Withdrawn
-
2004
- 2004-02-03 NO NO20040485A patent/NO20040485L/no not_active Application Discontinuation
- 2004-02-11 ZA ZA200401103A patent/ZA200401103B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US7002018B2 (en) | 2006-02-21 |
| IN192178B (https=) | 2004-03-06 |
| NO20040485L (no) | 2004-04-02 |
| WO2003014086A1 (en) | 2003-02-20 |
| PL373892A1 (en) | 2005-09-19 |
| EP1417172A1 (en) | 2004-05-12 |
| US20040254223A1 (en) | 2004-12-16 |
| EP1417172A4 (en) | 2005-05-11 |
| JP2005519862A (ja) | 2005-07-07 |
| ZA200401103B (en) | 2006-04-26 |
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