EA200400081A1 - ANALYTICAL SYSTEM WITH HIGH PASSAGE CAPACITY - Google Patents
ANALYTICAL SYSTEM WITH HIGH PASSAGE CAPACITYInfo
- Publication number
- EA200400081A1 EA200400081A1 EA200400081A EA200400081A EA200400081A1 EA 200400081 A1 EA200400081 A1 EA 200400081A1 EA 200400081 A EA200400081 A EA 200400081A EA 200400081 A EA200400081 A EA 200400081A EA 200400081 A1 EA200400081 A1 EA 200400081A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- probes
- anchors
- combination according
- preferred
- area
- Prior art date
Links
Landscapes
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Данное изобретение относится к композициям, аппаратуре и способам, пригодным для одновременного проведения множества биологических или химических анализов с высокой пропускной способностью с использованием повторяющихся совокупностей зондов. Комбинация по изобретению содержит поверхность, которая включает множество тест-областей, по меньшей мере две из которых и в предпочтительном воплощении по меньшей мере двадцать из которых в основном являются одинаковыми, где каждая из тест-областей содержит совокупность близких якорных молекул. Якоря связаны с бифункциональными линкерами, где каждый включает участок, специфичный по меньшей мере к одному из якорей, и участок, который представляет зонд, специфичный к интересующей мишени. Полученная совокупность зондов используется для анализа на присутствие или определение активности одной или более молекул-мишеней, которые специфически взаимодействуют с зондами. В предпочтительном воплощении тестируемая проба подвергается обработке защитой от нуклеаз перед ее контактированием с комбинацией по изобретению.Отчет о международном поиске был опубликован 2003.12.11.This invention relates to compositions, apparatus, and methods suitable for simultaneously conducting a variety of high throughput biological or chemical analyzes using repetitive sets of probes. A combination according to the invention comprises a surface that includes a plurality of test areas, at least two of which, and in a preferred embodiment, at least twenty of which are basically the same, where each of the test areas contains a collection of nearby anchor molecules. Anchors are associated with bifunctional linkers, where each includes an area specific to at least one of the anchors, and an area that represents a probe specific to the target of interest. The resulting set of probes is used to analyze the presence or determination of the activity of one or more target molecules that specifically interact with the probes. In a preferred embodiment, the test sample is treated with protection from nucleases before it is contacted with the combination according to the invention. The international search report was published 2003.12.11.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/888,413 US20030096232A1 (en) | 1997-12-19 | 2001-06-26 | High throughput assay system |
PCT/US2002/020039 WO2003002750A2 (en) | 2001-06-26 | 2002-06-26 | High throughput assay system |
Publications (2)
Publication Number | Publication Date |
---|---|
EA200400081A1 true EA200400081A1 (en) | 2005-06-30 |
EA011415B1 EA011415B1 (en) | 2009-02-27 |
Family
ID=40849123
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200400081A EA011415B1 (en) | 2001-06-26 | 2002-06-26 | Solution for lysis of cells or providing their permeability and methods of detecting a nucleic acid target |
Country Status (1)
Country | Link |
---|---|
EA (1) | EA011415B1 (en) |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6238869B1 (en) * | 1997-12-19 | 2001-05-29 | High Throughput Genomics, Inc. | High throughput assay system |
US6200781B1 (en) * | 1999-06-25 | 2001-03-13 | Integrated Genetic Devices, Ltd. | Apparatus, system and method for automated execution and analysis of biological and chemical reactions |
-
2002
- 2002-06-26 EA EA200400081A patent/EA011415B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EA011415B1 (en) | 2009-02-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KG MD TJ TM |
|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): KZ RU |