EA200300220A1 - METHOD OF OBTAINING IMIDAZO [1,2-C] [2,3] BENZODIAZEPINES AND OBTAINED INTERMEDIATE PRODUCTS FOR THIS METHOD - Google Patents
METHOD OF OBTAINING IMIDAZO [1,2-C] [2,3] BENZODIAZEPINES AND OBTAINED INTERMEDIATE PRODUCTS FOR THIS METHODInfo
- Publication number
- EA200300220A1 EA200300220A1 EA200300220A EA200300220A EA200300220A1 EA 200300220 A1 EA200300220 A1 EA 200300220A1 EA 200300220 A EA200300220 A EA 200300220A EA 200300220 A EA200300220 A EA 200300220A EA 200300220 A1 EA200300220 A1 EA 200300220A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- benzodiazepines
- intermediate products
- obtained intermediate
- imidazo
- obtaining
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 229940049706 benzodiazepine Drugs 0.000 title abstract 2
- 150000001557 benzodiazepines Chemical class 0.000 title abstract 2
- 239000013067 intermediate product Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
В заявке описываются способ получения соединений общей формулы (1), а также не известные до настоящего времени соединения общих формул (5 и 6), представляющие собой промежуточные продукты для получения предлагаемых в изобретении бензодиазепинов общей формулы (1).Международная заявка была опубликована вместе с отчетом о международном поиске.The application describes a process for the preparation of compounds of general formula (1), as well as compounds of general formulas (5 and 6) that are not known to date, which are intermediate products for the preparation of the general formula (1) benzodiazepines proposed in the invention. The international application was published together with international search report.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10041671A DE10041671C1 (en) | 2000-08-10 | 2000-08-10 | Process for the preparation of imidazo [1,2-c] [2,3] benzodiazepines and phenylacetic acid esters and oxazole derivatives as intermediates in their preparation |
| PCT/EP2001/008661 WO2002012247A1 (en) | 2000-08-10 | 2001-07-26 | Method for the production of imidazo-(1,2-c)(2,3)-benzodiazepines and intermediates in the production thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200300220A1 true EA200300220A1 (en) | 2003-08-28 |
| EA005570B1 EA005570B1 (en) | 2005-04-28 |
Family
ID=7653689
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200300220A EA005570B1 (en) | 2000-08-10 | 2001-07-26 | Method for the production of imidazo-(1,2-c)(2,3)-benzodiazepines and intermediates in the production thereof |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US6784292B2 (en) |
| EP (1) | EP1307460B1 (en) |
| JP (1) | JP2004505981A (en) |
| KR (1) | KR20030021263A (en) |
| CN (1) | CN1205213C (en) |
| AT (1) | ATE260921T1 (en) |
| AU (2) | AU7851201A (en) |
| BG (1) | BG107519A (en) |
| BR (1) | BR0112810A (en) |
| CA (1) | CA2417804A1 (en) |
| CZ (1) | CZ2003676A3 (en) |
| DE (2) | DE10041671C1 (en) |
| DK (1) | DK1307460T3 (en) |
| EA (1) | EA005570B1 (en) |
| EE (1) | EE200300058A (en) |
| ES (1) | ES2217173T3 (en) |
| HR (1) | HRP20030174A2 (en) |
| HU (1) | HUP0301500A3 (en) |
| IL (1) | IL154165A0 (en) |
| MX (1) | MXPA02012913A (en) |
| NO (1) | NO20030605D0 (en) |
| NZ (1) | NZ523479A (en) |
| PL (1) | PL359586A1 (en) |
| PT (1) | PT1307460E (en) |
| SK (1) | SK2892003A3 (en) |
| TR (1) | TR200401281T4 (en) |
| UA (1) | UA79737C2 (en) |
| WO (1) | WO2002012247A1 (en) |
| YU (1) | YU8903A (en) |
| ZA (1) | ZA200301862B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2007119361A1 (en) * | 2006-03-17 | 2009-08-27 | 三菱瓦斯化学株式会社 | Method for producing quinazolin-4-one derivative |
| KR200453637Y1 (en) * | 2009-06-23 | 2011-05-19 | (주)대양스톤 | A fixing device of a bowl for sink |
| CN104557533A (en) * | 2015-01-22 | 2015-04-29 | 中国石油大学(华东) | Method for catalytic synthesis of acetoin short chain fatty acid ester by using phosphotungstic acid |
| CN104498543B (en) * | 2015-01-22 | 2017-10-31 | 中国石油大学(华东) | A kind of method of lipase-catalyzed synthesis 3-hydroxy-2-butanone fatty acid ester |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19604919A1 (en) * | 1996-02-01 | 1997-08-07 | Schering Ag | New 2,3-benzodiazepine derivatives, their production and use as medicines |
| HUP9701325A1 (en) * | 1997-07-31 | 2000-08-28 | Gyógyszerkutató Intézet Kft. | New 2,3-benzodiazepine derivatives |
-
2000
- 2000-08-10 DE DE10041671A patent/DE10041671C1/en not_active Expired - Lifetime
-
2001
- 2001-07-26 CZ CZ2003676A patent/CZ2003676A3/en unknown
- 2001-07-26 SK SK289-2003A patent/SK2892003A3/en unknown
- 2001-07-26 CA CA002417804A patent/CA2417804A1/en not_active Abandoned
- 2001-07-26 EP EP01956566A patent/EP1307460B1/en not_active Expired - Lifetime
- 2001-07-26 AU AU7851201A patent/AU7851201A/en active Pending
- 2001-07-26 DE DE50101634T patent/DE50101634D1/en not_active Expired - Fee Related
- 2001-07-26 BR BR0112810-8A patent/BR0112810A/en not_active IP Right Cessation
- 2001-07-26 IL IL15416501A patent/IL154165A0/en unknown
- 2001-07-26 NZ NZ523479A patent/NZ523479A/en unknown
- 2001-07-26 YU YU8903A patent/YU8903A/en unknown
- 2001-07-26 AU AU2001278512A patent/AU2001278512B2/en not_active Ceased
- 2001-07-26 TR TR2004/01281T patent/TR200401281T4/en unknown
- 2001-07-26 ES ES01956566T patent/ES2217173T3/en not_active Expired - Lifetime
- 2001-07-26 AT AT01956566T patent/ATE260921T1/en not_active IP Right Cessation
- 2001-07-26 PT PT01956566T patent/PT1307460E/en unknown
- 2001-07-26 KR KR10-2003-7001796A patent/KR20030021263A/en not_active Application Discontinuation
- 2001-07-26 HU HU0301500A patent/HUP0301500A3/en unknown
- 2001-07-26 CN CNB018139876A patent/CN1205213C/en not_active Expired - Fee Related
- 2001-07-26 UA UA2003032066A patent/UA79737C2/en unknown
- 2001-07-26 PL PL01359586A patent/PL359586A1/en not_active Application Discontinuation
- 2001-07-26 EE EEP200300058A patent/EE200300058A/en unknown
- 2001-07-26 JP JP2002518222A patent/JP2004505981A/en active Pending
- 2001-07-26 MX MXPA02012913A patent/MXPA02012913A/en active IP Right Grant
- 2001-07-26 WO PCT/EP2001/008661 patent/WO2002012247A1/en not_active Application Discontinuation
- 2001-07-26 DK DK01956566T patent/DK1307460T3/en active
- 2001-07-26 US US10/344,156 patent/US6784292B2/en not_active Expired - Fee Related
- 2001-07-26 EA EA200300220A patent/EA005570B1/en not_active IP Right Cessation
-
2003
- 2003-02-04 BG BG107519A patent/BG107519A/en unknown
- 2003-02-07 NO NO20030605A patent/NO20030605D0/en not_active Application Discontinuation
- 2003-03-06 ZA ZA200301862A patent/ZA200301862B/en unknown
- 2003-03-10 HR HR20030174A patent/HRP20030174A2/en not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ KZ KG MD TJ TM |
|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): BY RU |