EA200200162A1 - LIPEPEPIPEPTIDES DEACYLATION METHOD - Google Patents

LIPEPEPIPEPTIDES DEACYLATION METHOD

Info

Publication number
EA200200162A1
EA200200162A1 EA200200162A EA200200162A EA200200162A1 EA 200200162 A1 EA200200162 A1 EA 200200162A1 EA 200200162 A EA200200162 A EA 200200162A EA 200200162 A EA200200162 A EA 200200162A EA 200200162 A1 EA200200162 A1 EA 200200162A1
Authority
EA
Eurasian Patent Office
Prior art keywords
lipepepipeptides
deacylation
deacylation method
core
lipodepsipeptide
Prior art date
Application number
EA200200162A
Other languages
Russian (ru)
Inventor
Адам Дзозеф Крюзман
Паланиаппан Кулантхаивел
Майкл Джон Родригез
Original Assignee
Эли Лилли Энд Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эли Лилли Энд Компани filed Critical Эли Лилли Энд Компани
Publication of EA200200162A1 publication Critical patent/EA200200162A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Настоящее изобретение раскрывает способ деацилирования липодепсипептида с получением соответствующего ядра. Также описаны продукты, полученные этим способом (например, ядро псевдомицина, представленное структурами (I) или (II)).Международная заявка была опубликована вместе с отчетом о международном поиске.The present invention discloses a method for deacylation of a lipodepsipeptide to form the corresponding core. Also described are products obtained by this method (for example, the pseudomycin core represented by structures (I) or (II)). The international application was published together with an international search report.

EA200200162A 1999-07-15 2000-06-08 LIPEPEPIPEPTIDES DEACYLATION METHOD EA200200162A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14396899P 1999-07-15 1999-07-15
PCT/US2000/015018 WO2001005815A1 (en) 1999-07-15 2000-06-08 Process for deacylation of lipodepsipeptides

Publications (1)

Publication Number Publication Date
EA200200162A1 true EA200200162A1 (en) 2002-06-27

Family

ID=22506494

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200200162A EA200200162A1 (en) 1999-07-15 2000-06-08 LIPEPEPIPEPTIDES DEACYLATION METHOD

Country Status (11)

Country Link
EP (1) EP1198471A1 (en)
JP (1) JP2003505042A (en)
CN (1) CN1361791A (en)
AU (1) AU5310600A (en)
BR (1) BR0012481A (en)
CA (1) CA2378868A1 (en)
EA (1) EA200200162A1 (en)
HU (1) HUP0202315A2 (en)
MX (1) MXPA02000458A (en)
NO (1) NO20020183L (en)
WO (1) WO2001005815A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002232176B2 (en) 2001-02-19 2006-06-15 Takara Bio Inc. Cyclic peptide
DE10335584B4 (en) * 2003-07-31 2006-06-29 Philipps-Universität Marburg Process for the preparation of cyclic molecules
US20060004185A1 (en) * 2004-07-01 2006-01-05 Leese Richard A Peptide antibiotics and peptide intermediates for their prepartion
DE102004060750A1 (en) * 2004-12-15 2006-07-13 Sanofi-Aventis Deutschland Gmbh Process for the deacylation of lipopeptides
TW201035111A (en) 2008-12-23 2010-10-01 Biosource Pharm Inc Antibiotic compositions for the treatment of gram negative infections
US8415307B1 (en) 2010-06-23 2013-04-09 Biosource Pharm, Inc. Antibiotic compositions for the treatment of gram negative infections
IN2015DN01633A (en) * 2012-09-24 2015-07-03 Dsm Sinochem Pharm Nl Bv

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0460882B1 (en) * 1990-06-07 1996-07-24 Eli Lilly And Company Lipopeptide deacylase

Also Published As

Publication number Publication date
AU5310600A (en) 2001-02-05
CN1361791A (en) 2002-07-31
HUP0202315A2 (en) 2002-10-28
NO20020183L (en) 2002-03-13
EP1198471A1 (en) 2002-04-24
JP2003505042A (en) 2003-02-12
WO2001005815A1 (en) 2001-01-25
MXPA02000458A (en) 2002-07-02
BR0012481A (en) 2002-04-02
NO20020183D0 (en) 2002-01-14
CA2378868A1 (en) 2001-01-25

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