EA200000997A1 - HOMOGENEOUS PHARMACEUTICAL COMPOSITIONS CONTAINING ABAKAVIR, LAMIVUDIN AND ZIDOVUDIN - Google Patents

HOMOGENEOUS PHARMACEUTICAL COMPOSITIONS CONTAINING ABAKAVIR, LAMIVUDIN AND ZIDOVUDIN

Info

Publication number
EA200000997A1
EA200000997A1 EA200000997A EA200000997A EA200000997A1 EA 200000997 A1 EA200000997 A1 EA 200000997A1 EA 200000997 A EA200000997 A EA 200000997A EA 200000997 A EA200000997 A EA 200000997A EA 200000997 A1 EA200000997 A1 EA 200000997A1
Authority
EA
Eurasian Patent Office
Prior art keywords
abakavir
lamivudin
zidovudin
pharmaceutical compositions
compositions containing
Prior art date
Application number
EA200000997A
Other languages
Russian (ru)
Inventor
Робин Карри
Сьюнил Джейн
Аллен Уэйн Вуд
Original Assignee
Глаксо Груп Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Глаксо Груп Лимитед filed Critical Глаксо Груп Лимитед
Publication of EA200000997A1 publication Critical patent/EA200000997A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Abstract

Раскрыта фармацевтическая композиция, содержащая гомогенную комбинацию абакавира, ламивудина и зидовудина в количестве, при котором достигается противовирусная эффективность, способ получения такой композиции и способ подавления вируса иммунодефицита человека (ВИЧ), при котором вводят такую композицию ВИЧ-инфицированному пациенту.Международная заявка была опубликована вместе с отчетом о международном поиске.A pharmaceutical composition is disclosed containing a homogeneous combination of abacavir, lamivudine and zidovudine in an amount that achieves antiviral efficacy, a method for producing such a composition and a method for suppressing human immunodeficiency virus (HIV) in which such a composition is administered to an HIV-infected patient. with an international search report.

EA200000997A 1998-04-29 1999-04-26 HOMOGENEOUS PHARMACEUTICAL COMPOSITIONS CONTAINING ABAKAVIR, LAMIVUDIN AND ZIDOVUDIN EA200000997A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9809213.3A GB9809213D0 (en) 1998-04-29 1998-04-29 Pharmaceutical compositions
PCT/EP1999/002794 WO1999055372A1 (en) 1998-04-29 1999-04-26 Homogeneous pharmaceutical compositions comprising abacavir, lamivudine and zidovudine

Publications (1)

Publication Number Publication Date
EA200000997A1 true EA200000997A1 (en) 2001-06-25

Family

ID=10831228

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200000997A EA200000997A1 (en) 1998-04-29 1999-04-26 HOMOGENEOUS PHARMACEUTICAL COMPOSITIONS CONTAINING ABAKAVIR, LAMIVUDIN AND ZIDOVUDIN

Country Status (23)

Country Link
EP (1) EP1083932A1 (en)
JP (1) JP2002512979A (en)
KR (1) KR20010043128A (en)
CN (1) CN1411380A (en)
AP (1) AP2000001971A0 (en)
AU (1) AU4135599A (en)
BR (1) BR9910071A (en)
CA (1) CA2330391A1 (en)
EA (1) EA200000997A1 (en)
EE (1) EE200000646A (en)
GB (1) GB9809213D0 (en)
HR (1) HRP20000732A2 (en)
HU (1) HUP0101622A3 (en)
ID (1) ID26955A (en)
IL (1) IL139181A0 (en)
IS (1) IS5675A (en)
NO (1) NO20005418L (en)
NZ (1) NZ507745A (en)
PL (1) PL343710A1 (en)
SK (1) SK16212000A3 (en)
TR (1) TR200003157T2 (en)
WO (1) WO1999055372A1 (en)
ZA (1) ZA200005922B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1146882A2 (en) * 1998-05-29 2001-10-24 The University Of Florida Combination of zidovudine (azt) with nucleoside analogs for treatment of feline immunodeficiency virus
US6875773B1 (en) 1998-05-29 2005-04-05 Ben M. Dunn Combination therapy for treatment of FIV infection
GB9820417D0 (en) * 1998-09-18 1998-11-11 Glaxo Group Ltd Antiviral combinations
US7074417B2 (en) * 2000-10-13 2006-07-11 Advancis Pharmaceutical Corporation Multiple-delayed release anti-viral product, use and formulation thereof
SK285383B6 (en) * 2002-04-23 2006-12-07 Lupin Limited Modified release compositions present in the matrix with long action
AR040242A1 (en) * 2002-06-04 2005-03-23 Glaxo Group Ltd PHARMACEUTICAL COMPOSITIONS
CN100335125C (en) * 2003-06-03 2007-09-05 上海现代药物制剂工程研究中心 Interferon nasal spray powder with long service for detoxication and anti-bacteria
WO2006114709A1 (en) * 2005-04-25 2006-11-02 Aurobindo Pharma Limited Pharmaceutical compositions of antiretrovirals
US20070059360A1 (en) * 2005-07-29 2007-03-15 Ashish Jaiswal Water-dispersible anti-retroviral pharmaceutical compositions
ES2279707B1 (en) * 2005-11-10 2008-06-01 Combino Pharm, S.L. ORAL FORMULATIONS THAT INCLUDE 3'-AZIDONUCLEOSIDS.
CN101878032A (en) * 2007-10-02 2010-11-03 埃默里大学 Potent combinations of zidovudine and drugs that select for the K65R mutation in the HIV polymerase
WO2009092002A1 (en) * 2008-01-17 2009-07-23 Duquesne University Of The Holy Spirit Antiretroviral drug formulations for treatment of children exposed to hiv/aids
PT2531027E (en) * 2010-01-27 2015-09-16 Viiv Healthcare Co Therapeutic combination comprising dolutegravir, abacavir and lamivudine
US20130115237A1 (en) 2010-06-09 2013-05-09 Vaccine Technologies, Incorporated Therapeutic immunization in hiv infected subjects to augment antiretroviral treatment
RU2014140177A (en) 2012-03-05 2016-04-27 Сипла Лимитед PHARMACEUTICAL ANTIRETROVIRAL COMPOSITIONS
US10004721B2 (en) 2012-10-23 2018-06-26 Cipla Limited Pharmaceutical antiretroviral composition
PE20201496A1 (en) 2013-06-13 2020-12-29 Akebia Therapeutics Inc COMPOSITIONS AND METHODS TO TREAT ANEMIA

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY115461A (en) * 1995-03-30 2003-06-30 Wellcome Found Synergistic combinations of zidovudine, 1592u89 and 3tc
GB9622681D0 (en) * 1996-10-31 1997-01-08 Glaxo Group Ltd Pharmaceutical compositions

Also Published As

Publication number Publication date
IS5675A (en) 2000-10-20
HUP0101622A3 (en) 2003-09-29
BR9910071A (en) 2000-12-26
ID26955A (en) 2001-02-22
IL139181A0 (en) 2001-11-25
EP1083932A1 (en) 2001-03-21
AP2000001971A0 (en) 2000-12-31
SK16212000A3 (en) 2001-07-10
HRP20000732A2 (en) 2001-02-28
EE200000646A (en) 2002-04-15
HUP0101622A2 (en) 2002-03-28
ZA200005922B (en) 2001-10-23
CA2330391A1 (en) 1999-11-04
TR200003157T2 (en) 2001-01-22
AU4135599A (en) 1999-11-16
CN1411380A (en) 2003-04-16
NZ507745A (en) 2004-07-30
KR20010043128A (en) 2001-05-25
WO1999055372A1 (en) 1999-11-04
GB9809213D0 (en) 1998-07-01
NO20005418L (en) 2000-11-29
PL343710A1 (en) 2001-08-27
NO20005418D0 (en) 2000-10-27
JP2002512979A (en) 2002-05-08

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