EA199700281A1 - DNA MOLECULE CODING FOR PROTEIN L1 PAPILLOMA VIRUS TYPE 11 TYPE OF HUMAN, EXPRESSING VECTOR, METHOD OF OBTAINING PURIFIED VIRUS-LIKE PARTICLES - Google Patents

DNA MOLECULE CODING FOR PROTEIN L1 PAPILLOMA VIRUS TYPE 11 TYPE OF HUMAN, EXPRESSING VECTOR, METHOD OF OBTAINING PURIFIED VIRUS-LIKE PARTICLES

Info

Publication number
EA199700281A1
EA199700281A1 EA199700281A EA199700281A EA199700281A1 EA 199700281 A1 EA199700281 A1 EA 199700281A1 EA 199700281 A EA199700281 A EA 199700281A EA 199700281 A EA199700281 A EA 199700281A EA 199700281 A1 EA199700281 A1 EA 199700281A1
Authority
EA
Eurasian Patent Office
Prior art keywords
type
protein
dna molecule
particles
human
Prior art date
Application number
EA199700281A
Other languages
Russian (ru)
Other versions
EA000969B1 (en
Inventor
Катрин Дж. Хофманн
Катрин У. Янсен
Майкл П. Ниппер
Джозеф Г. Джойс
Хью Э. Джордж
Дэйл И. Лехман
Original Assignee
Мерк Энд Ко., Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27022236&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA199700281(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Мерк Энд Ко., Инк. filed Critical Мерк Энд Ко., Инк.
Publication of EA199700281A1 publication Critical patent/EA199700281A1/en
Publication of EA000969B1 publication Critical patent/EA000969B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Данное изобретение относится к синтетической молекуле ДНК, кодирующей очищенный белок L1 вируса папилломы типа 11 человека, и ее производным.Международная заявка была опубликована вместе с отчетом о международном поиске.This invention relates to a synthetic DNA molecule encoding a purified human papillomavirus type 11 L1 protein and its derivatives. The international application was published together with an international search report.

EA199700281A 1995-03-30 1996-03-26 Isolated dna sequence, expression vector of dna sequence and process for production virus-like particles EA000969B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41357195A 1995-03-30 1995-03-30
US41357295A 1995-03-30 1995-03-30
PCT/US1996/004117 WO1996030520A2 (en) 1995-03-30 1996-03-26 Synthetic hpv6/11 hybrid l1 dna encoding human papillomavirus type 11 l1 protein

Publications (2)

Publication Number Publication Date
EA199700281A1 true EA199700281A1 (en) 1998-04-30
EA000969B1 EA000969B1 (en) 2000-08-28

Family

ID=27022236

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199700281A EA000969B1 (en) 1995-03-30 1996-03-26 Isolated dna sequence, expression vector of dna sequence and process for production virus-like particles

Country Status (21)

Country Link
US (1) US6159729A (en)
EP (1) EP0817852B1 (en)
JP (1) JP3918877B2 (en)
KR (1) KR100441477B1 (en)
CN (1) CN1154732C (en)
AT (1) ATE247712T1 (en)
AU (1) AU708111B2 (en)
CZ (1) CZ291375B6 (en)
DE (1) DE69629556T2 (en)
DK (1) DK0817852T3 (en)
EA (1) EA000969B1 (en)
ES (1) ES2203691T3 (en)
HU (1) HU228490B1 (en)
IL (1) IL117591A0 (en)
NO (1) NO320086B1 (en)
NZ (1) NZ306663A (en)
PL (1) PL183299B1 (en)
PT (1) PT817852E (en)
SK (1) SK283998B6 (en)
WO (1) WO1996030520A2 (en)
ZA (1) ZA962526B (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK35897A3 (en) * 1994-09-22 1998-02-04 Merck & Co Inc Isolated and purified dna molecule, encoding human papillomavirus type 6a, method of expression, pharmaceutical composition, a vaccine and use
GB9621091D0 (en) 1996-10-09 1996-11-27 Fondation Pour Le Perfectionem Attenuated microorganisms strains and their uses
WO1998044944A2 (en) * 1997-04-08 1998-10-15 Merck & Co., Inc. Stabilized human papillomavirus formulations
EA200100236A1 (en) * 1998-08-14 2001-08-27 Мерк Энд Ко., Инк. METHOD OF CLEANING VIRAL PARTICLES LIKE THE HUMAN PAPILLOMA VIRUS
DE19840263C1 (en) * 1998-09-03 2000-05-25 Deutsches Krebsforsch Papillomaviruses, means for their detection and for the therapy of diseases caused by them
US6380364B1 (en) 1998-11-23 2002-04-30 Loyola University Of Chicago Chimeric biotin-binding papillomavirus protein
AUPP765398A0 (en) 1998-12-11 1999-01-14 University Of Queensland, The Treatment of papillomavirus infections
KR20010093290A (en) 1999-02-05 2001-10-27 폴락 돈나 엘. Human papillomavirus vaccine formulations
US7001995B1 (en) * 1999-08-25 2006-02-21 Merck & Co., Inc. Synthetic human papillomavirus genes
SI1421200T1 (en) * 2001-08-23 2007-04-30 Merck & Co Inc Fluorescent multiplex hpv pcr assays using multiple fluorophores
EP1302550A1 (en) * 2001-10-10 2003-04-16 King Car Food Industrial Co., Ltd. Method and detector for identifying subtypes of human papilloma viruses
BRPI0407877A (en) * 2003-03-07 2006-03-01 Merck & Co Inc peptide-protein conjugate, vaccine for the prevention or amelioration of influenza virus infection, and, method for inducing an immune response in a patient
ES2381964T3 (en) 2003-03-24 2012-06-04 Merck Sharp & Dohme Corp. Optimized expression of L1 of HPV 31 in yeast
IL156670A0 (en) * 2003-06-26 2004-01-04 Zvi Zolotariov Aloe suppositories
AU2004275865B2 (en) * 2003-09-25 2008-09-25 Third Wave Technologies, Inc. Detection of HPV
MY140664A (en) * 2003-09-29 2010-01-15 Merck Sharp & Dohme Optimized expression of hpv 45 l1 in yeast
MY139500A (en) * 2003-11-12 2009-10-30 Merck Sharp & Dohme Optimized expression of hpv 58 l1 in yeast
KR101203403B1 (en) * 2004-03-24 2012-11-21 머크 샤프 앤드 돔 코포레이션 Optimized expression of HPV 52 L1 in yeast
EP1819835B1 (en) 2004-12-08 2010-08-04 Gen-Probe Incorporated Detection of nucleic acids from multiple types of human papillomaviruses
CN101341257B (en) * 2004-12-10 2012-10-10 杰纳罗生物系统有限责任公司 Human papilloma virus (HPV) detection using nucleic acid probes, microbeads and fluorescent-activated cell sorter (FACS)
ATE474066T1 (en) * 2005-11-15 2010-07-15 Genoid Kft METHOD FOR DETECTING PATHOGENS USING MOLECULAR BEACONS
US8080643B2 (en) * 2006-09-05 2011-12-20 Third Wave Technologies, Inc. HPV primers
CN101200696B (en) * 2007-11-14 2011-07-20 山东大学 Yeast proliferation model of human papilloma virus as well as constructing method and uses
KR20090073987A (en) * 2007-12-31 2009-07-03 정운원 Primer, Probe, DNA Chip containg the Same and Method for Detecting Human Papillomavirus and Detection Kit Thereof
US9376727B2 (en) 2010-05-25 2016-06-28 Qiagen Gaithersburg, Inc. Fast results hybrid capture assay and associated strategically truncated probes
EP2638058B1 (en) 2010-11-12 2017-01-11 Merck Sharp & Dohme Corp. Enolase peptide conjugate vaccines against staphylococcus aureus
EP2722389B1 (en) * 2011-06-15 2018-03-07 Hong Jin Kim Method for enhancing the production yield of human papillomavirus l1 protein
US10513541B2 (en) 2015-12-04 2019-12-24 Xiamen University Mutant of L1 protein of human papillomavirus type 11
US20220001002A1 (en) * 2018-09-26 2022-01-06 Xiamen University Mutant of l1 protein of human papillomavirus type 51

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1298211B1 (en) * 1991-07-19 2006-07-12 The University Of Queensland Polynucleotide segment of HPV16 Genome
PT1618888E (en) * 1993-03-09 2011-04-08 Univ Rochester Production of human papillomavirus capsid protein and virus-like particles

Also Published As

Publication number Publication date
US6159729A (en) 2000-12-12
WO1996030520A3 (en) 1996-11-07
AU5527796A (en) 1996-10-16
NO320086B1 (en) 2005-10-24
WO1996030520A2 (en) 1996-10-03
PL322588A1 (en) 1998-02-02
ATE247712T1 (en) 2003-09-15
AU708111B2 (en) 1999-07-29
PT817852E (en) 2003-12-31
NO974514L (en) 1997-11-27
CZ291375B6 (en) 2003-02-12
IL117591A0 (en) 1996-07-23
EP0817852B1 (en) 2003-08-20
KR100441477B1 (en) 2004-10-06
JP3918877B2 (en) 2007-05-23
ES2203691T3 (en) 2004-04-16
JPH11503313A (en) 1999-03-26
EP0817852A2 (en) 1998-01-14
HU228490B1 (en) 2013-03-28
NO974514D0 (en) 1997-09-29
SK283998B6 (en) 2004-07-07
KR19980703391A (en) 1998-10-15
EA000969B1 (en) 2000-08-28
HUP9801608A3 (en) 1999-04-28
ZA962526B (en) 1996-09-04
PL183299B1 (en) 2002-06-28
CN1154732C (en) 2004-06-23
CZ309197A3 (en) 1998-02-18
DE69629556D1 (en) 2003-09-25
DE69629556T2 (en) 2004-06-17
CN1185810A (en) 1998-06-24
NZ306663A (en) 1999-10-28
SK129397A3 (en) 1998-05-06
DK0817852T3 (en) 2003-11-24
HUP9801608A2 (en) 1998-10-28

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

PD4A Registration of transfer of a eurasian patent in accordance with the succession in title
PD4A Registration of transfer of a eurasian patent in accordance with the succession in title
MK4A Patent expired

Designated state(s): RU