EA042491B1 - LAMELLAR WASHING COMPOSITION FOR PERSONAL HYGIENE - Google Patents

Description

Technical field

The present invention relates to liquid detergent compositions suitable for topical application to the human body, such as skin and hair. In particular, the present invention relates to compositions, preferably sulfate-free lamellar phase personal care detergent compositions. Preferably the compositions lather well, are stable and have a very mild action. Preferably they have a consumer acceptable odour.

State of the art

Consumers prefer very mild and moisturizing sulphate-free personal care cleanser compositions that still have excellent sensory characteristics such as rich lathering and a soft and smooth skin feeling usually after just one shower. They must also have an acceptable odour. Acyl isethionates are known to be very mild surfactants and are the ideal surfactant to provide the user with a soft and moist feeling with the desired bulky, thick foam. However, liquid detergents with a high content of fatty isethionates tend to crystallize due to the low water solubility of acyl isethionates. Acylglycinate in combination with acyl isethionates also provides very mild systems which may have unacceptable stability due to the limited water solubility of these surfactants. The use of acyl isethionates with a certain specific range of chain lengths (eg, percentages of acyl isethionates with C ₁₂ or lower) can solve stability problems in the acyl glycinate, acyl isethionate system, but, as Applicants have found, can create problems associated with insufficient foaming. Attempts to address foaming problems (while maintaining stability) may also lead to other problems such as unacceptable odour. Thus, obtaining compositions that are both mild, stable, have acceptable foaming and odor characteristics is extremely difficult. Surprisingly, it has been found that for particular compositions containing an acyl isethionate and an acyl glycinate, optionally in the presence of amphoteric surfactants, the addition of an acyl glutamate surfactant can simultaneously provide mild action, stability, acceptable foaming and acceptable odor if the components are chosen appropriately.

More specifically, these characteristics can be simultaneously achieved in compositions containing (1) from 1 to 15%, preferably from 1 to 10 wt.% acyl isethionate; and (2) from 0.5 to 12%, preferably from 1 to 10 wt.% acylglycinate, while the amount of C ₁₂ -C ₁₈ glycinate is more than 50% of the content of glycinates with a chain length of C ₈ , C ₁₀ and C ₁₂ - From ₁₈ ; (3) from 0.5 to 12%, preferably from 1 to 10 wt.% divalent anionic C ₈ -C ₁₈ acylglutamate; (4) 0 to 10%, preferably 0.5 to 5%, amphoteric surfactant; (5) from 0.1 to 10 wt.% lamellar structuring agent, where the specified lamellar structuring agent is selected from the group consisting of C ₈ -C ₁₈ -alkyl fatty acids, alkyl alcohols and mixtures thereof, while the mass content of acylglutamate in the composition as an active component is more than 50% by weight of acyl isethionate; and wherein the distribution along the chain length for the acyl isethionate is such that the C ₁₂ chain is from 60 to 100%, preferably from 70 to 100%, while the pH of said composition is from 6 to 8, more preferably from 6.5 to 7 .5, and most preferably from 6.7 to 7.3.

Mild liquid detergents containing acyl isethionates are known.

U.S. Patent No. 5,415,810 issued May 16, 1995 to Robert S. Lee et al. discloses a detergent composition in which an acyl isethionate is solubilized by adding a zwitterionic surfactant, the amount of zwitterionic surfactant being half the weight percent acyl isethionate. However, this patent does not disclose specific acyl isethionate (with a defined chain length), acylglycinate, acylglutamate systems according to the present invention.

WO 2011/117650 published September 29, 2011 to Stephen Moss O'Connor et al. discloses concentrated surfactant compositions containing acyl isethionate surfactants; most of these compositions are solid or pasty at room temperature and are soluble/fluid only at higher temperatures. In addition, most of these compositions contain sulfate surfactants as solubilizers. Due to the desire of consumers to use sulfate-free systems and the soft feel that these sulfate-free systems provide, such sulfate-containing systems are not preferred. Compositions according to the present invention are not discussed in this document.

US Patent Application Publication No. 2013/0189212 dated July 25, 2013 to Arun Harachandra Jawale et al. discloses a surfactant composition containing acyl isethionates in combination with acyl glycinates and alkyl betaine which is clear, concentrated and flowable; however, the pH of this system is reported to be below pH 6. Acyl isethionates tend to

- 1 042491 hydrolysis at a pH that is not neutral; therefore, to ensure long-term stability, it is more desirable that these systems be stable at pH 7. In addition, specific ratios of acylglutamate to acyl isethionate and specific acyl isethionates are not disclosed in this document.

US Patent Application Publication No. 2013/0143784 dated June 6, 2013 to Kirolos Rizk et al discloses a composition that contains acyl isethionate, acyl glycinate and cocamidopropyl betaine. Specific ratios of acylglutamate and acyl isethionate and specific acyl isethionates are not disclosed.

Preferably the compositions according to the present invention are lamellar. Lamellar compositions exhibit high zero shear viscosity, which is favorable for settling and/or structuring, while exhibiting significant shear thinning resulting in good composition pour distribution. In general, lamellar phase compositions are easily identified by cross-polarization microscopy by their characteristic focal cone shape and buttery streaked texture, while hexagonal phase exhibits an angular fan-like texture. Micellar phases, on the other hand, are optically isotropic.

It should be understood that lamellar phases can be formed in a wide variety of surfactant systems using a wide variety of lamellar phase inducers as described, for example, in US Pat. et al., issued September 14, 1999. In general, the transition from micellar to lamellar phase depends on the effective average surfactant head group area, tail length, and tail volume. The use of branched surfactants or surfactants with smaller head groups or bulky tails are also effective ways to induce micellar to lamellar phase transitions.

One way to characterize lamellar dispersions involves measuring the viscosity at low shear rate (using, for example, a stress rheometer) using an additional inductor (eg, oleic acid or isostearic acid). At higher amounts of inductor, low shear viscosity will increase significantly.

Another way to measure lamellar dispersions is through the use of freeze-chipping electron microscopy. The micrographs typically show a lamellar microstructure and dense lamellar droplet packing (typically in the size range of about 2 microns).

As noted earlier, none of the above compositions, or any other of those compositions known to the authors of the present invention, do not disclose compositions in which the ratio of acylglutamate to acyl isethionate (in systems also including acylglycinate and, optionally, an amphoteric substance) is chosen in a specific way , and in which the chain length distribution of the acyl isethionate is specifically controlled to simultaneously provide mild-acting compositions that are stable, have acceptable foam, and have an acceptable odor.

Brief description of the invention

In one aspect of the present invention, liquid aqueous lamellar personal care detergent compositions are provided, comprising:

1) from 1 to 15%, preferably from 1 to 10 wt.% C ₈ -C ₂₀ acyl isethionate;

2) from 0.5 to 12%, preferably from 1 to 10%, more preferably from 1 to 8 wt. % acylglycinate, while the amount of C ₁₂ -C ₁₈ glycinate is more than 50% of the content of glycinates with a chain length of C8, C10 and C12-C18;

3) 0.5 to 12%, preferably 1 to 10% divalent anionic C ₈ -C ₁₈ acylglutamate; And

4) 0 to 10%, preferably 0.5 to 5% or 1.0 to 4% by weight of an amphoteric surfactant; And

5) preferably from 0.1 to 10 wt.% structuring agent, where the specified lamellar structuring agent is selected from the group consisting of C ₈ -C ₁₈ -alkyl fatty acids, alkyl alcohols and mixtures thereof;

while the mass content of acylglugamate in the composition as an active ingredient is more than 50% relative to the mass of acyl isethionate;

where the chain length distribution for the acyl isethionate is such that the C ₁₂ chain is from 60 to 100%, more preferably from 70 to 100%; and wherein the pH of said composition is from 6 to 8, more preferably from 6.5 to 7.5, and most preferably from 6.7 to 7.3.

Preferably, the amount of glycinate with a chain length of C12 to C18 is predominant (more than 50%, preferably more than 60%, more preferably from 65 to 100%, even more preferably from 80 to 100% of the total content of glycinates with a chain length of C ₈ , Xiu and C ₁₂ -C ₁₈ This further enhances foaming Preferably the C 10 glycinate present is a saturated decanoyl glycinate, and the C ₁₀ glycinate is preferably substantially free of unsaturated C ₁₀ glycinate, ie undecylenyl glycine.

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The combination of these properties provides sufficient Q2 to provide acceptable foaming and odor characteristics, and in combination with acylglutamate, good stability is achieved. Thus, the compositions are stable, have acceptable foam (greater than 300 ml using the Sita foam assay as determined in the protocol) and have an acceptable odor.

Detailed description of the invention

Except in the examples or where expressly stated otherwise, all numerical values in this specification indicating amounts of material or reaction conditions, physical properties of the materials, and/or applications are to be understood as modified by the word approximately. All quantities are by weight of the final composition unless otherwise indicated.

It should be noted that in defining any concentration or amount range, any particular upper concentration may be associated with any particular lower concentration or amount.

For the avoidance of doubt, the word containing is intended to mean the word including, but not necessarily consisting of or composed of. In other words, the steps or options listed are not meant to be exhaustive.

The disclosure of the invention described herein should be considered as covering all embodiments that are listed in the claims as multiple dependent on each other, regardless of the fact that the claims can be given without multiple dependence or duplication.

In one form, the present invention provides compositions that, based on the specific selection of the ratio of acylglutamate to acyl isethionate and the choice of acyl isethionate chain length, provide compositions that are both mild, stable, have acceptable foam [greater than 300 ml using the Sita foam assay, as determined in the protocol] and have an acceptable odour.

In particular, said composition contains:

1) from 1 to 15%, preferably from 1 to 10% wt.% C ₈ -C ₂₀ acyl isethionate;

2) 0.5 to 12%, preferably 1 to 10% by weight of acylglycinate;

3) from 0.5 to 12%, preferably from 1 to 10 wt.% divalent anionic C ₈ -C ₁₈ acylglutamate; And

4) from 0 to 10%, preferably from 0.5 to 5 wt.% amphoteric surfactant; And

5) preferably from 0.1 to 10 wt.% structuring agent, where the specified lamellar structuring agent is selected from the group consisting of C ₈ -C ₁₈ -alkyl fatty acids, alkyl alcohols and mixtures thereof, and this mass content of acylglutamate in the composition as an active component is more than 50% by weight of acyl isethionate;

while the chain length distribution for the acyl isethionate is such that the C ₁₂ chain is from 60 to 100%, preferably from 70 to 100%;

wherein the pH of said composition is from 6 to 8, more preferably from 6.5 to 7.5, and most preferably from 6.7 to 7.3.

Preferably the C ₁₀ glycinate present is a saturated decanoyl glycinate, and the Cu glycinate is preferably substantially free of unsaturated Ci glycinate, ie undecylenoyl glycine.

More specifically, the compositions are described below.

Surfactants.

Mild anionic surfactants are preferably included in the detergent compositions of the present invention. Preferably, sulfate-containing surfactants and soap are present in an amount of less than 3%, 2%, or 1% by weight, or preferably absent. Surfactants are compounds containing hydrophobic and hydrophilic parts, the action of which reduces the surface tension in aqueous solutions in which they are dissolved. In addition to the isethionates, glycinates, and glutamates that make up the compositions of the present invention, other suitable surfactants that can be used include sulfosuccinates, sacrosinates, taurates, alaninates, threoninates, and mixtures thereof. Preferably, the content of hard sulfate-containing anionic surfactants such as SLES (sodium laureth sulfate), SLS (sodium lauryl sulfate), sodium trideceth sulfate, as well as soaps and mixtures thereof is from 3.2 to 1 wt.%, and preferably they are absent in the composition .

Anionic surfactants.

The detergent composition according to the present invention preferably contains one or more mild synthetic anionic detergent actives other than soap. The content of soft synthetic surfactants used is not less than 5, 4, 3 and 2 wt.% and not more than 8, 12, 16 and 20 wt.%.

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Solubilizing cations may be used, such as sodium, potassium, ammonium or substituted ammonium cations. Sodium and potassium are preferred.

The detergent composition according to the present invention preferably contains C ₈ -C ₁₈ acylglycinate(s). These surfactants can be prepared by reacting C ₈ -C ₁₈ fatty acid chloride with glycine in the presence of sodium, potassium or ammonium hydroxide to give the corresponding C ₈ -C ₁₈ acylglycinate.

Preferred acyl isethionates include sodium lauroyl isethionate and sodium cocoyl isethionate.

Preferably, the amount of glycinate with chain length from C ₁₂ to C ₁₈ is predominant (more than 50%, preferably more than 60%, more preferably from 65 to 100%. More preferably, from 80 to 100% of the total content of glycinates with chain length C ₈ is present, Xu and C ₁₂ -C ₁₈ Without wishing to be bound by a particular theory, it is believed that the predominance of C ₁₂ -C ₁₈ relative to C ₈ -C _1o results in increased foaming. contains Xiu unsaturated glycinate, i.e. undecylenoylglycine.

The acylglycinates are preferably present in an amount of 0.5 to 12%, preferably 1 to 10% by weight

The detergent composition according to the present invention preferably contains C ₈ -C ₁₈ acylglutamate(s). These surfactants are prepared by reacting C ₈ -C ₁₈ fatty acid chloride with glutamic acid in the presence of sodium, potassium or ammonium hydroxide to give the corresponding C ₈ -C ₁₈ acylglutamate. Preferably, the glutamates are potassium myristoylglutamate and potassium cocoylglutamate.

The acylglutamates are preferably present in an amount of 0.5 to 12%, preferably 1 to 10% by weight.

The detergent composition according to the present invention preferably contains C ₈ -C ₁₈ acyl isethionates. These esters are obtained by reacting an alkali metal isethionate with mixed aliphatic carboxylic acids having from 6 to 18 carbon atoms.

The acyl isethionates are preferably present in an amount of 1 to 10%, preferably 2 to 10% by weight. The total content of C ₁₂ isethionate in the chain length distribution for acyl isethionate is 60 to 100%, more preferably 70 to 100% and most preferably 80 to 100%. When the content of acylglutamate is preferably 0.5 to 12% or 1 to 10% by weight, the content of acyl isethionate should be more than 50%.

The acyl isethionate may be an alkoxylated isethionate such as that described in US Pat. No. 5,393,466 by Ilardi et al. entitled Fatty Acid Esters of Polyalkoxylated isethonic acid; issued February 28, 1995; included in the present invention by reference. This compound has the general formula

RC-O(O)-C(X)HC(Y)H2-(OCH-CH2) _m -SO ₃ M ⁺ , where R is an alkyl group containing from 8 to 18 carbon atoms, m is an integer from 1 to 4, X and Y are hydrogen or an alkyl group containing 1 to 4 carbon atoms, and M ⁺ is a monovalent cation such as, for example, sodium, potassium or ammonium.

A preferred combination is sodium lauroyl isethionate and potassium myristoyl glutamate. Another preferred combination is sodium cocoyl isethionate and potassium cocoyl glutamate.

The anionic detergent surfactant(s) that can be used in the present invention may be C ₈ -C ₂₂ alkyl chains of alkyl sulfosuccinates, methyl acyl taurates, acyl sarcosinates, acylalaninates, acyl threoninates, alkyl glyceryl ether sulfonates, alkyl sulfates, acyl lactylates, paraffin sulfonates, linear alkyl benzene sulfonates , alpha-sulfonated fatty acid esters, alkyl ester carboxylates, phosphate alkyl esters, ethoxylated phosphate alkyl esters, alpha-olefin sulfates and alkyl ester sulfates, and mixtures thereof. The counterion on these surfactants is selected from, but not limited to, Na, K, NH ₄ , N(CH ₂ CH ₂ OH) ₃ .

Amphoteric surfactants.

In the present invention, one or more amphoteric surfactants can be preferably used as co-surfactant and stabilizer. The content of amphoteric surfactants is preferably not less than 3%, 2%, 1% or 0% and not more than 4%, 5% or 6% by weight.

Suitable amphoteric surfactants include simple betaines of formula R1-N ⁺ -(R ² )(R ³ )CH ₂ CO ₂ and amidobetaines of formula

R1-CONH(CH2)nN ⁺ -(R2)(R3)CH2CO2 where n is 2 or 3.

In both formulas, R ¹ , R ² and R ³ are as defined above. In particular, R ¹ may be a mixture of C ₁₂ and C ₁₄ alkyl groups derived from coconut oil such that

- 4 042491 at least half, preferably at least three quarters of the groups R ¹ contain from 10 to 14 carbon atoms. R ² and R ³ are preferably methyl.

Also, the amphoteric detergent may be a sulfobetaine of the formula

R1-N+-(R2)(R3)(CH2)3SO3- or R1-CONH(CH2)m-N+-(R2)(R3)(CH2)3SO3 where m is 2 or 3, or variations thereof in which -( CH ₂ ) ₃ SO ₃ - is substituted with -CH2C(OH)(H)CH2SO3-.

In these formulas, R ¹ , R ² and R ³ are as discussed above.

Amphoacetates and diamphoacetates also include possible zwitterionic and/or amphoteric substances suitable for use, such as, for example, sodium lauroamphoacetate, sodium cocoamphoacetate and mixtures thereof and the like.

Suitable amphoteric surfactants include hydroxysultaines, betaines and amphoacetates.

Preferred amphoteric substances include alkylamidopropyl betaine, in particular cocamidopropyl betaine, alkylamidopropylhydroxysultaine, in particular cocamidopropylhydroxysultaine, alkylamphoacetate, in particular sodium lauroamphoacetate, and from a mixture.

Non-ionic surfactants.

One or more non-ionic surfactants may optionally be used as co-surfactants in the detergent composition according to the present invention. Non-ionic surfactants are preferably used in an amount of at least 3%, 2%, 1% or 0% by weight and at most 4%, 5% or 6% by weight. Particularly suitable non-ionic surfactants include the reaction products of compounds containing a hydrophobic group and a reactive hydrogen atom, for example aliphatic alcohols, acids, amides or alkylphenols, with alkylene oxides, in particular ethylene oxide or alone, or with propylene oxide. Specific nonionic detergents are condensates of alkyl (C ₆ -C ₂₂ )phenolethylene oxide, condensation products of aliphatic (C ₈ -C ₁₈ ) primary or secondary linear or branched alcohols with ethylene oxide, and products obtained by condensing ethylene oxide with reaction products of propylene oxide and ethylenediamine. Other so-called nonionic detergents include long chain tertiary amine oxides, long chain tertiary phosphine oxides and dialkyl sulfoxides and the like.

Preferred non-ionic surfactants include carboxylic acid/alcohol ethoxylates with the following structures:

a) HOCH ₂ (CH ₂ ) _n (CH ₂ CH ₂ O) _x H or

b) HOOC(CH2)m(CH2CH2O)y H;

where m, n independently <18; and x, y are independently >1, preferably m, n are independently 6 to 18; x, y independently take values from 1 to 30;

c) HOOC(CH2)i-CH=CH-(CH2)k(CH2CH2O)z H;

where i, k independently take values from 5 to 15; and z is independently 5 to 50. Preferably i, k are independently 6 to 12; and z independently takes values from 15 to 35.

Non-ionic compounds may also include sugar amides such as polysaccharide amides. In particular, the surfactant may be one of the lactobionamides described in US Pat. from the sugar amides described in Kelkenberg's US Pat.

carboxylic acids.

It is also preferable to use C ₁₂ -C ₁₈ alkylcarboxylic acids. It is preferable to use lauric (C ₁₂ ), myristic (C ₁₄ ) or palmitic (C ₁₆ ) acids alone or in combination. Preferably, the carboxylic acid(s) are used in an amount of at least 2%, 1% or 0% by weight and at most 4%, 5% or 6% by weight. Care must be taken not to increase the content of lauric acid to the point where it inhibits the foaming of the surfactant and also causes stability and crystallization problems.

In addition to or instead of the usual carboxylic acids, other structuring agents can be used; as structuring agents, starch, lauryl alcohol, PEG distearates or polymeric thickeners can be used. Preferably, the content of these structuring agents is at least 3%, 2%, 1% or 0% and at most 7%, 8%, 9% or 10% by weight.

Lamellar structuring agents.

As indicated, the compositions according to the present invention are lamellar. Such compositions should have a minimum of 0.1 or 1 or 2% lamellar structurants and a maximum of 10 or 9 or 8 wt.%, preferably 0.5 to 10 wt.%, more preferably 1 to 5 wt.% and most preferably from 2 to 4 wt.%.

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Preferred lamellar structuring agents are selected from the group consisting of

C8-C18 alkyl fatty acids, alkyl alcohols and mixtures thereof. Especially preferred are lauric acid, lauryl alcohol or mixtures thereof.

Cationic skin conditioning agents.

A suitable component in the compositions according to the present invention is a cationic skin conditioning agent or a polymer such as, for example, cationic celluloses. The cationic polymers are preferably used in amounts as low as about 0.1 to 2% and up to as high as the solubility limit of the particular polymer, or preferably not more than about 4 to 5 wt %, provided that the solubility limit of the particular cationic polymer or polymer blends is not exceeded.

Cationic cellulose is available from Amerchol Corp. (Edison, NJ, USA) in their series of polymers Polymer JR (trademark) and LR (trademark) in the form of salts, which are products of the reaction of hydroxyethyl cellulose with trimethylammonium-substituted epoxide, called in the industry (according to the nomenclature of the Fragrance and Cosmetics Association and fragrances, CTFA, English: Cosmetic Toiletries and Fragrance Association) polyquaternium 10 (Polyquaternium 10). Another type of cationic cellulose includes polymeric quaternary ammonium salts, which are the reaction products of hydroxyethyl cellulose with lauryldimethylammonium-substituted epoxide, called in the industry (according to the CTFA nomenclature) Polyquaternium 24 (Polyquaternium 24). These materials are available from Amerchol Corp. (Edison, NJ, USA) under the trade name Polymer LM-200.

A particularly suitable type of cationic polysaccharide polymer that can be used is a cationic guar gum derivative such as guarhydroxypropyltrimonium chloride (commercially available from Rhone-Poulenc in their JAGUAR series). Examples are JAGUAR C-13S which has low cationic substitution and high viscosity, JAGUAR C15 which has moderate substitution and low viscosity, JAGUAR C17 (high substitution, high viscosity), JAGUAR C16 which is a hydroxypropylated cationic guar derivative with a low content of substituent groups as well as cationic quaternary ammonium groups, and JAGUAR 162, which is a high-clarity, medium-viscosity, low-substitution guar derivative; Jaguar Optima, which has a high degree of substitution and a low molecular weight; and Jaguar Excel , which has a low degree of substitution and high viscosity.

Particularly preferred cationic polymers are JAGUAR C13S, JAGUAR C15, JAGUAR C17 and JAGUAR C16 and JAGUAR C162, especially JAGUAR C13S, JAGUAR C14/BFG, Jaguar Optima and Jaguar Excel. JAGUAR C14/BFG is the same molecule as Jaguar C13 except boron has been replaced with a glyoxal crosslinker. Other cationic skin conditioning agents known in the art may be used provided they are compatible with the composition of the present invention.

Other suitable examples of the surfactants described above that can be used are described in Surface Active Agents and Detergents (Vol. I & II) by Schwartz, Perry & Berch, incorporated herein by reference in their entirety.

In addition, the detergent composition according to the present invention may contain from 0 to 15 wt.% of the following optional ingredients: fragrances; complexing agents such as tetrasodium salt of ethylenediaminetetraacetic acid (EDTA), ethane-1-hydroxy-1,1-diphosphonic acid (EHDP) or mixtures in an amount of from 0.01 to 1%, preferably from 0.01 to 0.05% ; and soluble dyes and the like; all of which are suitable for enhancing the appearance or cosmetic properties of a product.

The compositions may further contain antimicrobial agents such as caprylyl glycol, 2-hydroxy-4,2',4'-trichlorodiphenyl ether (DP300); preservatives such as methylisothiazolinone/methylchloroisothiazolinone (Kathon, MIT), dimethyloldimethylhydantoin/iodopropynylbutylcarbamate (Glydant XL-1000), parabens, sorbic acid, etc. and the like.

The compositions may also contain acyl mono- or diethanolamides present in coconut as foam enhancers, and highly ionizing salts such as sodium chloride and sodium sulfate can also be effectively used to increase viscosity. Preferably, highly ionizing salts, also known as electrolytes, are present in amounts of less than 5%, 4%, 3%, or 1% by weight.

Antioxidants, such as, for example, butylhydroxytoluene (BHT) and the like, can be effectively used in an amount of about 0.01% or more, if necessary.

Emollients.

The term emollient means a substance that softens or improves the elasticity, appearance and youthfulness of the skin (stratum corneum) by either increasing its moisture content, or adding or replacing lipids and other skin nutrients, or both together and preserving the skin soft by slowing down the decrease in its moisture content.

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Humectants which are also humectants such as polyols such as glycerol and propylene glycol and the like, and polyols such as polyethylene glycols such as Polyox WSR N-60K (PEG-45M) and the like, used in the preferred embodiment of the present invention. The humectants are preferably used in an amount of at least 3%, 2%, 1% or 0% by weight and at most 7%, 8%, 9% or 10% by weight.

Hydrophobic emollients with a weight average particle size below either 1000 or 500 µm in diameter are defined in the present invention as fine oils and are preferably used in an amount of at least 3, 2, 1 or 0 wt.% and a maximum of 20, 30, 40 or 50 wt. %.

These hydrophobic emollients include, but are not limited to, the following:

(a) silicone oils and modifications thereof such as linear and cyclic polydimethylsiloxanes; amino, alkyl, alkylaryl and aryl silicone oils;

(b) fats and oils, including natural fats and oils (triglycerides) such as jojoba, soybean, sunflower, rice bran, avocado, almond, olive, sesame, peach kernel, castor, coconut, mink fat; cacao butter; beef fat, pork fat; hardened oils obtained by hydrogenating the above oils; and synthetic mono-, di- and triglycerides such as myristic acid glyceride and 2-ethylhexanoic acid glyceride;

(c) waxes such as carnauba wax, spermaceti wax, beeswax, lanolin and their derivatives;

(d) hydrophobic plant extracts;

(e) hydrocarbons such as petrolatum, polybutene, liquid paraffins, microcrystalline wax, ceresin, squalene, pristane and mineral oil;

(f) higher alcohols such as lauryl, cetyl, stearyl, oleyl, behenyl alcohol, cholesterol and 2-hexidecanol;

(g) esters such as cetyl octanoate, myristyl lactate, cetyl lactate, isopropyl myristate, myristyl myristate, isopropyl palmitate, isopropyl adipate, butyl stearate, decyl oleate, cholesterol isostearate, glycerol monostearate, glycerol distearate, glycerol tristearate, alkyl lactate, alkyl citrate, and alkyl tartrate;

(h) essential oils and their extracts such as peppermint, jasmine, camphor, white cedar, orange, rue, turpentine, cinnamon, bergamot, satsum, calamus, pine, lavender, laurel, clove, thuja , eucalyptus, lemon, cinquefoil, thyme, peppermint, rose, sage, sesame, ginger, basil, juniper, lemongrass, rosemary, rosewood, avocado, grapefruit, grape seed, myrrh, cucumber Oil, Watercress Oil, Calendula Oil, Black Elderberry Oil, Geranium Oil, Linden Flower Oil, Amaranth Oil, Seaweed Oil, Ginkgo Oil, Ginseng Oil, Carrot Seed Oil, Guarana Oil, Tea Tree Oil, Jojoba Oil, Comfrey Oil, Oat Oil, Cocoa Butter , neroli oil, vanilla oil, green tea, hedeoma, aloe vera, menthol, cineole, eugenol, citral, citronellol, borneol, linalool, geraniol, evening primrose oil, camphor, thymol, spirantol (spirantol), pinene, lemon ene and terpenoid oils;

(i) mixtures of any of the foregoing and the like.

Preferred emollients include petrolatum; natural wax; partially or fully hydrogenated triglyceride oils; and their mixtures. Preferred triglyceride oils include soybean oil or sunflower oil.

Thickeners.

Compositions according to the present invention may be thickened. Examples of thickeners that can be used include polyethylene glycol distearates; starch; starch derivatives; waxes; and polymer thickeners. An example of a starch derivative is sodium hydroxypropyl starch phosphate.

Optional active agents.

Preferably, active agents other than conditioning agents, such as emollients or moisturizers as defined above, may be added to the inventive cleaning composition in a safe and effective amount during preparation to treat the skin while using the product. Suitable active ingredients include those which are water soluble or dispersible within the ranges indicated above. Suitable active agents may preferably be selected from antimicrobial and antifungal actives, vitamins, anti-acne actives, anti-wrinkle, skin atrophy and skin repair actives, skin barrier repairing actives, non-steroidal cosmetic soothing actives, artificial tanning and tanning accelerators, skin lightening actives, sunscreen actives, sebaceous stimulants, sebum inhibitors, antioxidants, protease inhibitors, skin tightening agents, antipruritic ingredients, hair growth inhibitors, 5-alpha reductase inhibitors, exfoliating enzyme stimulants, anti-glycation agents, local anesthetics or mixtures thereof, etc.

These active agents may be selected from water soluble active agents, fat soluble active agents, pharmaceutically acceptable salts and mixtures thereof. Preferably, these

- 7 042491 agents are soluble or dispersible in the proposed detergent composition. The term active agent in the present invention means personal care actives that can be used to provide a beneficial effect on the skin and/or hair and which are not usually used to impart a conditioning effect provided by the humectants and emollients described herein. invention above. The term "safe and effective amount" in the present invention means an amount of the active agent that is high enough to alter the condition being treated or to provide the desired skin care benefit, but low enough to avoid serious side effects. The term beneficial effect in the present text means a therapeutic, prophylactic and/or long-term beneficial effect associated with the treatment of a particular condition using one or more active agents described in the present invention. The specific safe and effective amount of the active ingredient will vary depending on the particular active agent, the ability of the active to penetrate the skin, the age, health and skin condition of the user, and other such factors. Preferably, the composition according to the present invention contains from about 0.01 to about 50%, more preferably from about 0.05 to about 25%, even more preferably from 0.1 to about 10%, and most preferably from 0.1 to about 5% of the active agent component based on the weight of the component.

Anti-acne actives may be effective in the treatment of acne vulgaris, a chronic disorder of the sebaceous follicles. Non-limiting examples of suitable anti-acne actives include keratolytics such as salicylic acid (o-hydroxybenzoic acid), salicylic acid derivatives such as 5-octanoylsalicylic acid and 4-methoxysalicylic acid, and resorcinol; retinoids such as retinoic acid and its derivatives (eg cis- and trans-), sulfur-containing D- and L-amino acids and their derivatives and salts, in particular their N-acetyl derivatives, mixtures thereof and the like.

Antimicrobial and antifungal actives can be effective in preventing the spread and growth of bacteria and fungi. Non-limiting examples of antimicrobial and antifungal actives include p-lactam drugs, quinolone drugs, ciprofloxacin, norfloxacin, tetracycline, erythromycin, amikacin, 2,4,4'-trichloro-2'-hydroxydiphenyl ether, 3,4,4'- trichlorobanilide (3,4,4'-trichlorobanilide), phenoxyethanol, triclosan; triclocarban; and mixtures thereof; and the like.

Anti-wrinkle, skin atrophy and skin repair actives can be effective in regenerating or rejuvenating the epidermal layer. These actives generally provide these desired skin care benefits by stimulating or maintaining the skin's natural sloughing process. Non-limiting examples of anti-wrinkle and skin atrophy actives include vitamins, minerals, and skin nutrients such as milk, vitamins A, E, and K, vitamin alkyl esters, including vitamin C alkyl esters, magnesium, calcium, copper, zinc, and other metal components; retinoic acid and its derivatives (eg cis- and trans-), retinal, retinol; retinol esters such as retinyl acetate, retinyl palmitate and retinyl propionate, vitamin B3 compounds (such as niacinamide and nicotinic acid), alpha hydroxy acids, beta hydroxy acids such as salicylic acid and its derivatives (such as 5-octanoylsalicylic acid, heptyloxy-4 -salicylic acid and 4-methoxysalicylic acid), mixtures thereof, etc.

Skin barrier repair actives are skin care actives that can help restore and regenerate the natural function of the epidermis as a water-retaining barrier. Non-limiting examples of skin barrier rebuilding actives include lipids such as cholesterol, ceramides, sucrose esters and pseudoceramides as disclosed in EP 556957; ascorbic acid; biotin; esters of biotin; phospholipids, mixtures thereof and the like.

Non-steroidal cosmetic soothing actives may be effective in preventing or treating skin inflammation. The soothing active enhances the beneficial effects on the appearance of the skin according to the present invention, for example, such agents contribute to a more uniform and acceptable skin tone or color. Non-limiting examples of cosmetic soothing agents include the following categories: propionic acid derivatives, acetic acid derivatives, fenamic acid derivatives, mixtures thereof, and the like. Many of these cosmetic soothing actives are described in US Patent No. 4,985,459 to Sunshine et al., issued January 15, 1991, the contents of which are hereby incorporated by reference in their entirety.

Fake tanning actives can help mimic natural tanning by increasing the level of melanin in the skin, or by giving the appearance of increasing the level of melanin in the skin. Non-limiting examples of tanning products and tanning accelerators include dihydroxyacetone; tyrosine; tyrosine esters such as ethyl tyrosinate and glucose tyrosinate; their mixtures and the like.

- 8 042491

Skin lightening actives may directly reduce the amount of melanin in the skin or provide such an effect through other mechanisms. Non-limiting examples of skin lightening actives suitable for purposes of the present invention include aloe extract, alpha-glyceryl-L-ascorbic acid, aminothyroxine, ammonium lactate, glycolic acid, hydroquinone, 4-hydroxyanisole, mixtures thereof, and the like.

Also suitable for use in the present invention are sunscreen actives. A wide variety of sunscreen agents are described in U.S. Patent No. 5,087,445 to Haffey et al., issued February 11, 1992; U.S. Patent No. 5,073,372 to Turner et al., issued December 17, 1991; , and in Cosmetics Science and Technology, Segarin et al., Chapter VIII, pp. 189 et seq., the contents of which are incorporated herein by reference in their entirety. Non-limiting examples of sunscreens suitable for use in the compositions of the present invention are selected from the group consisting of octylmethoxycinnamate (Parsol MCX) and butylmethoxybenzoylmethane (Parsol 1789), 2-ethylhexyl-p-methoxycinnamate, 2-ethylhexyl-N,N-dimethyl- paminobenzoate, p-aminobenzoic acid, 2-phenylbenzimidazole-5-sulfonic acid, oxybenzone, mixtures thereof and the like.

Sebaceous stimulants can increase the production of sebum by the sebaceous glands. Non-limiting examples of sebum stimulating actives include bryonic acid, dehydroepiandrosterone (DHEA), oryzanol, mixtures thereof, and the like.

Sebaceous secretion inhibitors can reduce the production of sebum by the sebaceous glands. Non-limiting examples of suitable sebum-inhibiting actives include aluminum hydroxychloride, corticosteroids, dehydroacetic acid and its salts, dichlorophenylimidazoledioxolane (available from Elubiol), mixtures thereof, and the like.

Protease inhibitors are also suitable as active substances in accordance with the present invention. Protease inhibitors can be divided into two main classes: proteinases and peptidases. Proteinases act on specific peptide bonds within proteins, while peptidases act on peptide bonds adjacent to the free amino or carboxyl group at the end of the protein and thus cleave the protein from the outside. Protease inhibitors suitable for use in the present invention include, but are not limited to, proteinases such as serine proteases, metalloproteases, cysteine proteases and aspartyl protease, and peptidases such as carboxypeptidases, dipeptidases and aminopeptidases, mixtures thereof, and the like.

Other agents suitable as active ingredients in accordance with the present invention are agents with a skin tightening effect. Non-limiting examples of skin tightening agents suitable for use in the compositions of the present invention include monomers that can bind the polymer to the skin, such as terpolymers of vinylpyrrolidone, methacrylic acid and a hydrophobic monomer consisting of long chain alkyl (meth)acrylates, mixtures thereof and the like.

Active ingredients in accordance with the present invention may also include antipruritic ingredients. Suitable examples of antipruritic ingredients suitable for use in the compositions of the present invention include hydrocortisone, methdilazine and trimeprazine, mixtures thereof, and the like.

Non-limiting examples of hair growth inhibitors suitable for use in the compositions of the present invention include 17-beta-estradiol, antiangiogenic steroids, turmeric extract, cyclooxygenase inhibitors, evening primrose oil, linoleic acid, and the like. Suitable 5-alpha reductase inhibitors such as ethinyl estradiol and genistein, mixtures thereof and the like.

Non-limiting examples of exfoliating enzyme stimulants suitable for use in the compositions of the present invention include alanine, aspartic acid, N-methylserine, serine, trimethylglycine, mixtures thereof, and the like.

A non-limiting example of an anti-glycation agent suitable for use in the compositions of the present invention is Amadorine (available from Barnet Products Distributor) and the like.

Solid modifiers of optical properties in the form of particles.

A suitable optional component of the compositions in accordance with the present invention is one or more solid optical property modifiers in the form of particles, preferably plate-shaped or plate-like light-reflecting particles. These particles preferably have an average particle size D ₅₀ in the range from about 25,000 to about 150,000 nm. For lamellar materials, the average particle size is the number average. It is assumed that the plates are round in shape with a circular surface diameter averaged over a large number of particles. The thickness of lamellar particles is considered a separate parameter. For example, the platelets may have an average particle size of 35,000 nm and an average thickness of 400 nm. The present invention contemplates a thickness in the range of about 100 to

- 9 042491 approximately 600 nm. Laser light scattering can be used for the measurement, and the light scattering data must be mathematically corrected from spherical to non-spherical. Optical and electron microscopy can be used to determine the average particle size. Thickness is usually determined only by optical or electron microscopy.

The refractive index of these particles may be at least about 1.8, typically from about 1.9 to about 4, for example, from about 2 to about 3, and from about 2.5 to 2.8.

Illustrative, but non-limiting examples of reflective particles are bismuth oxychloride (single crystal plates) and mica coated with titanium dioxide and/or iron oxide. Suitable bismuth oxychloride crystals are available from EM Industries, Inc. under the trademarks Biron® NLY-L-2X CO and Biron® Silver CO (where the plates are dispersed in castor oil); Biron® Liquid Silver (where the particles are dispersed in a stearic acid ester) and Nailsyn® IGO, Nailsyn® II C2X and Nailsyn® II Platinum 25 (where the plates are dispersed in nitrocellulose). Most preferred is a system in which bismuth oxychloride is dispersed in a C ₂ -C ₄₀ alkyl ester, such as Biron® Liquid Silver.

Suitable titanium dioxide coated mica plates include materials available from EM Industries, Inc. These include Timiron® MP-45 (particle size range 4900057000 nm), Timiron® MP-99 (particle size range 47000-57000 nm), Timiron® MP-47 (particle size range 28000-38000 nm), Timiron® MP-149 (particle size range 65000-82000 nm) and Timiron® MP-18 (particle size range 41000-51000 nm). The weight ratio of titanium dioxide coating to mica plate may range from about 1:10 to about 5:1, preferably from about 1:6 to about 1:7 by weight. Preferably, the compositions of the present invention are typically substantially free of titanium dioxide, except as required for the mica coating.

Suitable iron oxide and titanium dioxide coated mica plates include materials available from EM Industries, Inc. These include Timiron® MP-28 (particle size range 27000-37000 nm), Timiron® MP-29 (particle size range 47000-55000 nm) and Timiron® MP-24 (particle size range 56000-70000 nm).

Suitable iron oxide coated mica plates include materials available from EM Industries, Inc. These include Colorona® Bronze Sparkle (particle size range 28000-42000 nm), Colorona® Glitter Bronze (particle size range 65000-82000 nm), Colorona® Copper Sparkle (particle size range 25000-39000 nm) and Colorona® Glitter Copper (particle size range 25000-39000 nm). particle sizes 65000-82000 nm).

Suitable coatings for mica, other than titanium dioxide and iron oxide, can also provide the necessary optical properties required in accordance with the present invention. Such coated micas should also have a refractive index of at least about 1.8. Other coatings include silicon dioxide on mica plates.

Exfoliants.

The composition according to the present invention may contain particles with an average diameter greater than 50 µm to help remove dry skin. Without wishing to be bound by a particular theory, it is believed that the degree of exfoliation depends on particle size and morphology. Large and coarse particles tend to be very hard and irritating. Very small particles cannot serve as effective exfoliants. Such exfoliants useful in the art include natural minerals such as silica, talc, calcite, pumice, tricalcium phosphate; seeds such as rice, apricot seeds and so on; crushed shells such as almond and walnut shells; oatmeal; polymers such as polyethylene and polypropylene beads, flower petals and leaves; microcrystalline wax granules; jojoba ester granules; and the like. These exfoliants can have a variety of particle sizes and morphologies ranging from micron sizes up to several mm. They also have a range of hardness values. Some examples are given in table. A below.

Table A

Material Hardness (Mohs scale) Talc 1 Calcite 3 Pumice 4-6 Walnut shells 3-4 Dolomite 4 Polyethylene ~1

The compositions of the present invention typically have a viscosity in the range of 20,000 centipoise (cP) to 300,000 cP, preferably 50,000 to 200,000 cP, more preferably 80,000 to 160,000 cP, measured with a Brookfield T-A viscometer, 0.5 vol. /min, 60 seconds.

The compositions have a pH of 6.0 to 8.0, preferably 6.5 to 7.5, more preferably 6.7 to 7.3.

The present invention is described below in more detail using the following non-limiting examples. The examples are for illustrative purposes only and do not limit the present invention in any way. Physical analysis methods are described below.

Except for working and comparative examples, or where expressly stated otherwise, in the present invention, all numerical values indicating amounts or ratios of substances or reaction conditions, physical properties of substances and/or relating to application, should be understood as modified by the word approximately.

As used herein, the term including means the presence of the claimed features, integers, steps, components, but does not exclude the presence or addition of one or more features, integers, steps, components, or groups thereof.

Examples

All percentages in the present invention and examples are by weight unless otherwise indicated.

Example 1

Received several compositions according to the present invention and compositions of the comparison, and each was determined by the stability, odor and foam profile in accordance with the methods below.

In table. 1 shows the chain length distributions for the surfactants used. These descriptions apply to the surfactants used in the following examples.

Table 1. Chain length distribution for surfactants

Sodium coco yl isethionate 1 Sodium coco yl isethionate 2 Sodium lauroylisethionate Myristoyliset sodium ionate sodium lauroyl glycinate Sodium Cocoyl Glycinate Monosodium lauroyl glutamate Myristoyl glutamate potassium Potassium cocoyl glutame Sodium cocoyl glutamate C8 6% 3% 3% 6% 7% 6% 6% SU 6% 2% 2% 4% 5% 6% 6% C12 50% 72% 95% 90% 78% > 95% 63% 63% C14 18% 23% 100% 8% > 95% 20% 20% C16 10% 2% 4% 4% C18 10% <2% <2%

Table 2. Attempts to solve the problem of crystallization by using a lower amount of C ₁₂ in the composition as a whole

Formula 1 Formula 2 Formula 3 Formula 4 Formula 5 Sodium Cocoyl Glycinate 4.7% 4.7% 4.7% 4.7% 4.7% Sodium cocoyl isethionate 1 5.4% 0% 0% 0% 2.7% Sodium lauroyl isethionate 0% 5.4% 5.4% 5.4% 2.7% Cocamidopropyl betai n 1.6% 1.6% 1.6% 1.6% 1.6% Lauric acid 3% 3% 0% 0% 3% Myristic acid 0% 0% 0% 1.4% 0% capric acid 0% 0% 2.8% 1.4% 0% Foam volume/quality Unacceptable Acceptable Acceptable Acceptable Unacceptable 0 Stability Acceptable Unacceptable Acceptable Acceptable Acceptable Smell Acceptable Acceptable Unacceptable 0 Unacceptable Acceptable

In table. 2 describes preliminary unsuccessful attempts to solve the problem of crystallization of systems with a high content of acyl isethionate. It was noted that the use of sodium cocoyl isethionate 1 in Formula 1 resulted in acceptable stability and odor, however, the C ₁₂ chain length of these surfactants is known to result in optimum foam volume and the use of sodium cocoyl isethionate 1 resulted in unacceptable foaming properties. , especially with regard to foam volume. However, although the use of sodium lauroyl isethionate in formula 2 resulted in satisfactory foaming properties, crystallization stability was unacceptable due to the high content of substances with a chain length of C ₁₂ in the composition as a whole, consisting of glycinate, isethionate and lauric acid (used as a thickener and as a lamellar structuring agent). Formulas 3 and 4 were used to reduce the total content of substances with a chain length With ₁₂ in the composition by removing lauric acid and replacing it with capric and/or myristic acid. The addition of capric acid helped resolve the crystallization/stability problem, however the strong capric acid odor resulted in an unacceptable odor in the finished product. Another attempt to reduce the total C ₁₂ chain length materials in the formulation was made in formula 5 using a combination of sodium cocoyl isethionate 1 and sodium lauroyl isethionate, however, although this resulted in positive stability and odor characteristics, the foaming properties were unacceptable.

Table 3

Formula 6 Formula 7 Formula 8 Formula 9 Formula 10 Formula 11 Sodium Cocoyl Glycinate 2.35% 2.35% 2.35% 2.35% 2.35% 0% Sodium lauroyl glycinate 0% 0% 0% 0% 0% 2.35% Lauroylisethione t sodium 5.4% 0% 0% 0% 0% 0% Sodium cocoyl isethionate 2 0% 5.4% 5.4% 5.4% 5.4% 5.4% Sodium lauroylglutamate 3.04% 2.35% 3.04% 0% 3.0% 3.04% Sodium cocoylglutamate 0% 0% 0% 3.04% 0% 0% Cocamidopropyl betaine 1.6% 1.6% 1.6% 1.6% 1.6% 1.6% Lauric acid 3.2% 3.4% 3.2% 3.2% 3.0% 3.2% Foam volume/quality Acceptable Acceptable Acceptable Acceptable Acceptable Acceptable Stability unacceptable MO Unacceptable MO Acceptable Acceptable Acceptable Acceptable Smell Acceptable Acceptable Acceptable Acceptable Acceptable Acceptable

Addition of sodium acylglutamates.

In table. 3 details the addition of sodium lauroylglutamate and sodium cocoylglutamate to the formulation as a replacement for the sodium acylglycinate portion. Surprisingly, it was found that the addition of these acylglutamates, which are divalent anionic surfactants, resulted in greater solubilization and stability of the acyl isethionate, while maintaining good foaming and odor characteristics. It seems that to achieve acceptable solubilization and stability, it is necessary to add divalent anionic acylglutamate in an amount of at least 50% of the amount of acyl isethionate. Some undissolved matter was observed with sodium lauroyl isethionate, however, the use of sodium cocoyl isethionate 2 with a slightly lower C ₁₂ content removed this crystallization and, in combination with acylglutamate, did not adversely affect the foaming properties.

Table 4. Addition of potassium acylglutamates

Form 12 Form 13 Form 14 Form 15 Form 16 Form 17 Form 18 Form 19 Form 20 Form 21 Sodium Cocoyl Glycinate 2.35% 2.35% 2.35% 0% 2.35% 0% 0% 0% 0% 0% Sodium lauroyl glycinate 0% 0% 0% 2.35% 0% 2.35% 2.35% 2.35% 2.35% 2.35% Sodium lauroyl isethionate 0% 0% 0% 0% 5.4% 0% 0% 0% 0% 0% Sodium cocoyl isethionate 2 5.4% 5.4% 5.4% 5.4% 0% 5.4% 5.4% 5.4% 5.4% 0% Sodium myristoyl isethionate 0% 0% 0% 0% 0% 0% 0% 0% 0% 5.4% Sodium lauroylglutamate 0% 1.52% 2.28% 0% 0% 0% 0% 0% 0% 0% Potassium myristoylglutamate 3.04% 1.52% 0.76% 3.04% 3.04% 0% 0% 0% 0% 0% Potassium cocoylglutamate 0% 0% 0% 0% 0% 2.7% 2.16% 1.62% 1.08% 3.04% Cocamidopropyl Betaine 1.6% 1.6% 1.6% 1.6% 1.6% 1.6% 1.6% 1.6% 1.6% 1.6% Lauric acid 3.0% 3.2% 3.2% 3.2% 3.2% 2% 2% 2% 2% 2.4% Foam volume/quality Acceptable Acceptable Acceptable Acceptable Acceptable Acceptable Acceptable Acceptable Acceptable Acceptable Stability Acceptable Acceptable Acceptable Acceptable Acceptable Acceptable Acceptable Acceptable Acceptable Acceptable Smell Acceptable Acceptable Acceptable Acceptable Acceptable Acceptable Acceptable Acceptable Acceptable Acceptable

In table. 4 describes the addition of potassium acylglugamates to high acyl isethionate formulations. This resulted in even greater solubilization, which allowed both sodium lauroyl glycinate and sodium myristoyl isethionate and sodium lauroyl isethionate to be used with acceptable stability, odor and foaming properties. The use of potassium acylglutamates allows less glutamate to be added to solubilize the acyl isethionates.

- 12 042491

Table 5. Alteration and removal of amphoteric surfactant

Formula 9 Formula 22 Formula 23 Formula 24 Sodium Cocoyl Glycinate 2.35% 2.35% 2.35% 2.35% Sodium cocoyl isethionate 2 5.4% 5.4% 5.4% 5.4% Sodium cocoylglutamate 3.04% 3.04% 3.04% 3.04% Cocamidopropyl betai n 1.6% 0% 0% 0% Cocamidopropyl hydroxisultaine 0% 1.6% 0% 0% Sodium lauroamphoacetate 0% 0% 1.6% 0% Lauric acid 3.2% 3.2% 3.0% 2.4% Foam volume/quality Acceptable Acceptable Acceptable Acceptable Stability Acceptable Acceptable Acceptable Acceptable Smell Acceptable Acceptable Acceptable Acceptable

Tab. 5 shows the flexibility of the amphoteric surfactant even before removal. These changes show that, unlike prior art solutions, an amphoteric surfactant is not necessary for solubility or foaming properties in the presence of a glutamate surfactant.

Table 6 Modification and removal of monovalent anionic surfactant

Formula 25 Formula 26 Formula 27 Sodium Cocoyl Glycinate 0% 0% 0% Sodium laureth sulfate 0% 2.35% 0% Sodium lauroyl sarcosinate 0% 0% 2.35% Sodium cocoyl isethionate 2 5.4% 5.4% 5.4% Sodium cocoylglutamate 5.4% 3.04% 3.04% Cocamidopropyl Betaine 0% 0% 0% Cocamidopropylhydroxysultaine 0% 1.6% 0% Sodium lauroamphoacetate 0% 0% 1.6% Lauric acid 2.4% 2.4% 2.4% Foam volume/quality Acceptable Acceptable Acceptable Stability Acceptable Acceptable Acceptable Smell Acceptable Acceptable Acceptable

Tab. 6 shows flexibility for the monovalent anionic surfactant, up to and including elimination of the monovalent anionic surfactant in favor of acylglutamate.

Table 7. Variation of divalent anionic surfactant

Formula 28 Formula 29 Sodium Cocoyl Glycinate 2.35% 0% Sodium cocoyl isethionate 2 5.4% 5.4% Sodium cocoylglutamate 0% 0% Sodium laureth sulfosuccinate 3.04% 5.40% Cocamidopropyl Betaine 0% 0% Cocamidopropylhydroxysultaine 0% 1.6% Sodium lauroamphoacetate 0% 0% Lauric acid 2.4% 2.4% Foam volume/quality Acceptable Acceptable Stability Acceptable Acceptable Smell Acceptable Acceptable

Tab. 7 demonstrates the flexibility of the present invention for a divalent anionic surfactant by replacing the acylglutamate with sodium laureth sulfosuccinate, both in combination with the monovalent anionic surfactant and with the replacement of the monovalent anionic surfactant.

Methods.

A) Foaming method and evaluation.

Foaming was evaluated according to the following protocol:

equipment: Sita Foam Tester R-2000;

standard measurement parameters:

stirring speed: 1000 rpm, measurement time (one time interval): 45 seconds, dilution: 250 ml, sample size: 10 g.

-

Claims (14)

Methodology. 1) from 1 to 15 wt.% C ₈ -C _2O acyl isethionate; 1. Lamellar detergent composition for personal hygiene, containing: 1 - 1 2 1) Started one washing cycle with hot running water to make sure the vessel was clean and set the temperature of the vessel. 2. Composition according to claim 1, containing from 1 to 10 wt.% C8-C ₂₀ acyl isethionate, from 1 to 10 wt.% acylglycinate, from 1 to 10 wt.% divalent anionic C8-C18 acylglutamate and from 0.5 to 5% amphoteric surfactant. 2) from 0.5 to 12 wt.% acylglycinate, while the amount of C ₁₂ -C ₁₈ glycinate is more than 50% of the content of glycinates with a chain length of C8, C ₁₀ and C12-C18; 2) Fill the vessel with water (clean the vessel from the back of the device) with a stream of 38°C water. Provided a constant temperature of the water in the vessel, equal to 38°C+/-0.5°C for each measurement. 3. Composition according to claim 1 or 2, characterized in that the chain length distribution for the acyl isethionate is such that the C ₁₂ chain is between 70 and 100%. 3) from 0.5 to 12 wt.% divalent anionic C8-C18 acylglutamate; And 3) Weighed 10.0 g of test product into a 10 ml syringe. 4. Composition according to any one of claims 1 to 3, characterized in that said composition has a pH of 6.5 to 7.5, preferably 6.7 to 7.3. 4) up to 10% amphoteric surfactant; And 4 With _______ 25 C _______ 37 C _______ 45 C ₍ __ 50 C | Formulas must not show crystallization at all of the above (in bold) temperature-time points in order to be acceptable from a stability standpoint. C) Odor evaluation method. The sample was placed in a standard glass sample dish. The lid was removed and the odor was assessed. The sample was compared with a control sample similar in age and handling conditions. Odor testing was performed blindly by a person familiar with typical odor and formulation characteristics. While the present invention has been described with reference to specific embodiments thereof, it should be understood that numerous other forms and modifications of the present invention will be apparent to those skilled in the art. The appended claims and the description as a whole are intended to cover all obvious forms and modifications falling within the scope of the present invention. CLAIM 4) With care not to touch the walls of the vessel or the metal piston located in the middle of the vessel, the test product was placed on the bottom of the main vessel. 5. The composition according to any one of claims 1 to 4, containing glycinate with a chain length of C8-C18, while the amount of C ₁₂ -C ₁₈ glycinate is more than 50%, preferably more than 60% of the content of glycinates with a chain length of C8, C ₁₀ and C12-C18. 5) from 0.1 to 10 wt.% lamellar structuring agent, where the specified lamellar structuring agent is selected from the group consisting of C8-C ₁₈ -alkyl fatty acids, alkyl alcohols and mixtures thereof; while the mass content of acylglutamate in the composition as an active component is more than 50% relative to the mass of acyl isethionate; wherein the chain length distribution for the acyl isethionate is such that the C ₁₂ chain is from 60 to 100%; and wherein the pH of said composition is between 6 and 8. 5) The measurement parameters were checked, and the above parameters were entered. 6. A composition according to any one of claims 1 to 5, containing a lamellar structuring agent present in an amount of from 1 to 5 wt.%, more preferably from 2 to 4 wt.%. 6) Started the measurement, recorded the results. C) Method of stability. Temperature of the Week 7. Composition according to any one of claims 1 to 6, additionally containing a thickener. 8. Composition according to any one of claims 1 to 7, characterized in that said amphoteric surfactant is selected from the group consisting of alkylamidopropyl betaine, alkylamidopropylhydroxysultaine, alkylamphoacetate and mixtures thereof. - 14 042491 9. Composition according to any one of claims 1 to 8, characterized in that the acyl isethionate is sodium lauroyl isethionate and the acyl glutamate is potassium myristoyl glutamate. 10. Composition according to any one of claims 1 to 9, characterized in that said acyl isethionate is sodium cocoyl isethionate and said glutamate is potassium cocoyl glutamate. 11. Composition according to any one of claims 1 to 10, additionally containing an emollient. 12. A composition according to any one of claims 1 to 11 further comprising a cationic skin conditioning agent. 13. Composition according to any one of claims 1 to 12, characterized in that the viscosity range is from 20,000 to 300,000 centipoise, preferably from 50,000 to 200,000 centipoise, most preferably from 80,000 to 160,000 centipoise, as measured using a Brookfield T-A viscometer, 0.5 rpm, for 60 seconds. 14. Composition according to any one of claims 1 to 13, characterized in that the pH is from 6.0 to 8.0. Eurasian Patent Organization, EAPO Russia, 109012, Moscow, Maly Cherkassky per., 2