DOP2010000347A - QUINUCLIDINE DERIVATIVES AS M3 MUSCARINIC RECOVERY ANTAGONISTS - Google Patents

QUINUCLIDINE DERIVATIVES AS M3 MUSCARINIC RECOVERY ANTAGONISTS

Info

Publication number
DOP2010000347A
DOP2010000347A DO2010000347A DO2010000347A DOP2010000347A DO P2010000347 A DOP2010000347 A DO P2010000347A DO 2010000347 A DO2010000347 A DO 2010000347A DO 2010000347 A DO2010000347 A DO 2010000347A DO P2010000347 A DOP2010000347 A DO P2010000347A
Authority
DO
Dominican Republic
Prior art keywords
muscarinic
antagonists
recovery
quinuclidine derivatives
pharmaceutical compositions
Prior art date
Application number
DO2010000347A
Other languages
Spanish (es)
Inventor
Therapeutics Synergy Ltd Pulmagen
Rhonan Lee Ford
Andrew Nigel Mather
Antonio Mete
Richard James Bull
Elizabeth Anne Skidmore
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to DO2010000347A priority Critical patent/DOP2010000347A/en
Publication of DOP2010000347A publication Critical patent/DOP2010000347A/en

Links

Abstract

La invención proporciona los compuestos nombrados de fórmula (I), en la que R4 es una quinuclidina N-sustituida (I). composiciones farmacéuticas que los contienen y un proceso para preparacion las composiciones farmacéuticas. Tambien se divulga su uso en terapia para el tratamiento de afecciones Mediadas por receptores muscarinos M3, tales como la enfermedad pulmonar obstructiva crónica.The invention provides the named compounds of formula (I), wherein R 4 is an N-substituted quinuclidine (I). pharmaceutical compositions containing them and a process for preparing pharmaceutical compositions. Its use is also disclosed in therapy for the treatment of conditions mediated by M3 muscarine receptors, such as chronic obstructive pulmonary disease.

DO2010000347A 2010-11-12 2010-11-12 QUINUCLIDINE DERIVATIVES AS M3 MUSCARINIC RECOVERY ANTAGONISTS DOP2010000347A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DO2010000347A DOP2010000347A (en) 2010-11-12 2010-11-12 QUINUCLIDINE DERIVATIVES AS M3 MUSCARINIC RECOVERY ANTAGONISTS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DO2010000347A DOP2010000347A (en) 2010-11-12 2010-11-12 QUINUCLIDINE DERIVATIVES AS M3 MUSCARINIC RECOVERY ANTAGONISTS

Publications (1)

Publication Number Publication Date
DOP2010000347A true DOP2010000347A (en) 2010-12-15

Family

ID=44261608

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2010000347A DOP2010000347A (en) 2010-11-12 2010-11-12 QUINUCLIDINE DERIVATIVES AS M3 MUSCARINIC RECOVERY ANTAGONISTS

Country Status (1)

Country Link
DO (1) DOP2010000347A (en)

Similar Documents

Publication Publication Date Title
CO6321265A2 (en) COMPOUNDS OF 2-AMIDO-3-METHYL PIRROID PYRIMIDINONE PHENYL-REPLACED AS BACE-1 INHIBITORS COMPOSITIONS AND ITS USE
CO2017007679A2 (en) Derivatives of 1- (het) arylsulfonyl- (pyrrolidine or piperidine) -2-carboxamide and their use as trpa1 antagonists
ECSP10010606A (en) QUINUCLIDINE DERIVATIVES AS M3 MUSCARINIC RECEPTORS ANTAGONISTS
AR075729A1 (en) DERIVATIVES OF BENZOFURANILO, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND USE OF THE SAME IN THE TREATMENT OF OBESITY AND / OR DIABETES.
EA201490320A1 (en) TETRAHYDROPYRIDOPYRIDINE AND TETRAHYDROPYRIDOPYRIMIDINE COMPOUNDS AND THEIR APPLICATION AS MODEL C5A RECEPTOR MODULATORS
BR112016016844A2 (en) HETEROCYCLIC COMPOUNDS
EA201591195A1 (en) NEW QUINOLON DERIVATIVES
EA201492023A1 (en) REGULATORS OF THE COMPLEX WAY AND THEIR APPLICATION
PE20141167A1 (en) PYRIDOPYRAZINES SUBSTITUTED AS NOVEL PTK INHIBITORS
EA201391525A1 (en) GLYCOSIDE DERIVATIVES AND THEIR APPLICATION FOR THE TREATMENT OF DIABETES
SI2875011T1 (en) 5-ht3 receptor antagonists
BRPI0816219B8 (en) guanidine-containing compounds useful as muscarinic receptor antagonists, pharmaceutical composition and use
UY33278A (en) PYRIMIDINES REPLACED AS ANTAGONISTS OF THE PROTAGLANDIN D2 RECEPTOR
BR112014012459A2 (en) 2h-indazoles as ep2 receptor antagonists
EA201391797A1 (en) 3-SPIROCYCLIC PIPERIDINE DERIVATIVES AS AGONISTS OF GREELINE RECEPTORS
CO2017005806A2 (en) New benzimidazole derivatives as antihistamine agents
CO6300937A2 (en) DERIVATIVES OF 3-CARBOXIPROPIL-AMINOTETRALINA AND RELATED COMPOUNDS AS ANTIGONISTS OF OPIOID RECEPTORS MU
UY32744A (en) DERIVATIVES OF 2-CARBOXAMIDA-7-PIPERAZINIL-BENZOFURANO 774
ECSP13012838A (en) NEW BENZODIOXOL-PIPERAZINA COMPOUNDS
MX2013005966A (en) Novel benzofurane compounds.
UY33745A (en) DIFENYLAMINE DERIVATIVES: USES, SYNTHESIS PROCEDURE AND PHARMACEUTICAL COMPOSITIONS
AR080527A1 (en) A PYRIMIDINE REPLACED AS AN ANTAGONIST OF THE D2 POSTAGLANDINE RECEIVER
ATE546448T1 (en) UROTENSIN II RECEPTOR ANTAGONISTS
EA201390327A1 (en) Heterocyclyl Compounds As Histomine Hepathogen Receptor Ligands
EA201692090A1 (en) POLYCYCLIC ACTIVATORS HERG