DOP2010000240A -
ASSOCIATION BETWEEN A BIS-TIAZOLIO SALT OR ONE OF ITS PRECURSORS AND ARTEMISININE OR ONE OF ITS DERIVATIVES FOR THE TREATMENT OF SERIOUS PALUDISM
- Google Patents
ASSOCIATION BETWEEN A BIS-TIAZOLIO SALT OR ONE OF ITS PRECURSORS AND ARTEMISININE OR ONE OF ITS DERIVATIVES FOR THE TREATMENT OF SERIOUS PALUDISM
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Application filed by Sanofi Aventis, Centre Nat Rech Scient, Univ Montpellier IifiledCriticalSanofi Aventis
Publication of DOP2010000240ApublicationCriticalpatent/DOP2010000240A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems
(AREA)
Abstract
La invención tiene por objeto una asociación, que comprende una sal de bis-tiazolio, compuesto de fórmula (Vl) o uno de sus precursores, y artemisinina o uno de sus derivados. La invención tiene igualmente por objeto una composición farmacéutica que comprende al menos una sal de bis-tiazolio, compuesto de fórmula (Vl) o uno de sus precursores, y artemisinina o uno de sus derivados. La invención tiene también por objeto la utilización de dicha asociación para la preparación de un medicamento destinado al tratamiento o a la prevención del paludismo grave. La invención tiene finalmente por objeto un kit para el tratamiento o la prevención del paludismo graveA subject of the invention is an association, comprising a bis-thiazolium salt, compound of formula (Vl) or one of its precursors, and artemisinin or one of its derivatives. A subject of the invention is also a pharmaceutical composition comprising at least one bis-thiazolium salt, compound of formula (Vl) or one of its precursors, and artemisinin or one of its derivatives. The invention also aims at the use of said association for the preparation of a medicament intended for the treatment or prevention of severe malaria. The invention finally aims at a kit for the treatment or prevention of severe malaria
DO2010000240A2008-02-062010-08-04
ASSOCIATION BETWEEN A BIS-TIAZOLIO SALT OR ONE OF ITS PRECURSORS AND ARTEMISININE OR ONE OF ITS DERIVATIVES FOR THE TREATMENT OF SERIOUS PALUDISM
DOP2010000240A
(en)
COMPOUNDS DERIVED FROM HETEROCICLES REPLACED WITH MORFOLINA, INHIBITORS OF THE PI3 QUINASA ACTIVITY; PHARMACEUTICAL COMPOSITION THAT INCLUDES SUCH COMPOUNDS; PHARMACEUTICAL KIT; AND ITS USE FOR CANCER PROFILACTIC OR THERAPEUTIC TREATMENT.
COMPOUNDS DERIVED FROM NITROGEN HETEROCICLES; PHARMACEUTICAL COMPOSITION THAT INCLUDES SUCH COMPOUND; AND USE OF THE COMPOUND FOR THE TREATMENT OF PROLIFERATIVE DISEASES.
COMPOUNDS DERIVED FROM SULFONAMIDS; PREPARATION PROCEDURE; PHARMACEUTICAL COMPOSITION THAT INCLUDES SUCH COMPOUND; AND USE OF THE COMPOUND FOR THE TREATMENT OF CANCER, DYSLIPIDEMIA, DIABETES, OBESITY, INFECTION.
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ALISQUERENO SALT; PREPARATION PROCEDURE; PHARMACEUTICAL COMPOSITION THAT INCLUDES SUCH SALT; AND USE OF THE COMPOUND FOR THE TREATMENT OF DISEASES THAT CAN BE MODULATED BY THE INHIBITION OF THE RHENINE.
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