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Application filed by Warner Lambert CofiledCriticalWarner Lambert Co
Priority to DO2005000229ApriorityCriticalpatent/DOP2005000229A/en
Publication of DOP2005000229ApublicationCriticalpatent/DOP2005000229A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
La presente invención proporciona compuestos de la formula I: en los que R2, R3, R4, R5, R6, R7, X, y L tienen cualquiera de los valores definidos en la memoria descriptiva, y sales farmaceuticamente aceptables de los mismos, que son utiles como agentes en el tratamiento de trastomos y enfermedades del sistema nervioso central incluyendo el trastorno de deficit de atención con hiperactividad, dolor neuropatico, incontinencia urinaria, ansiedad, depresion, y esquizofrenia y fibromialgia. Tambien se proporcionan composiciones farmaceuticas que comprenden uno o mas compuestos de la formula I.The present invention provides compounds of the formula I: wherein R2, R3, R4, R5, R6, R7, X, and L have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, which are Useful as agents in the treatment of disorders and diseases of the central nervous system including attention deficit disorder with hyperactivity, neuropathic pain, urinary incontinence, anxiety, depression, and schizophrenia and fibromyalgia. Pharmaceutical compositions comprising one or more compounds of the formula I are also provided.
DO2005000229A2005-11-102005-11-10
PIRAZOLO [3,4-B] PIRIDINES AND THERAPEUTIC INDAZOLS
DOP2005000229A
(en)
Compounds derived from quinuclidine, acetylcholine a7 receptor ligands; its pharmaceutical composition; its use for the treatment of disorders of the central nervous system, especially affective and neurodegenerative diseases such as schizophrenia and Alzheimer's.