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Application filed by Bayer Healthcare AgfiledCriticalBayer Healthcare Ag
Priority to DO2005000184ApriorityCriticalpatent/DOP2005000184A/en
Publication of DOP2005000184ApublicationCriticalpatent/DOP2005000184A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Pyridine Compounds
(AREA)
Abstract
La presente invención se refiere a una nueva forma, termodinamicamente estable a temperatura ambiente, de la sal tosilato de 4-{4[({[4-cloro-3-(trifluorometil)fenil]amino}carbonil)amino]fenoxi}-N-metilpiridin-2carboxamida, a procedimientos para su preparación, a medicamentos que la comprenden y a su use en el control de trastornos.The present invention relates to a new, thermodynamically stable form at room temperature of the tosylate salt of 4- {4 [({[4-chloro-3- (trifluoromethyl) phenyl] amino} carbonyl) amino] phenoxy} -N -methylpyridin-2carboxamide, to procedures for its preparation, to medicines that comprise it and to use it in the control of disorders.
DO2005000184A2005-09-232005-09-23
THERMODYNAMICALLY STABLE FORM OF A TOSILATE SALT
DOP2005000184A
(en)
PROCEDURE TO PREPARE 4- (4 -! ((! 4-CHLORINE-3- (TRIFLUOROMETIL) PHENYL) AMBON) CARBONIL) AMINO! PHENOXI) -N-METHYL-PYRIDINE-2-CARBOXAMIDE AND ITS TOSILATE SALT
"Processes for the manufacture of hydrofluoroalkanes, for the manufacture of hydrofluoroalkanes, for the manufacture of hydrofluoroesters and compound"
PROCESS FOR THE PREPARATION OF 4- {4 [({[4-CHLORINE-3- (TRIFLUOROMETILO) -PHENYLL] AMINO} CARBONYL) AMINO] -3-FLUOROPHENOXY} -N-METHYLPIRIDINO-2-CARBOXAMIDE, ITS SALTS AND MONOHIDRATE
Diphosphate salt of n-[6-cis-2,6-dimethylmorpholin-4yl) pyridine-3yl]-2-methyl-4'-(trifluoromethoxy) [1,1'-biphenyl]-3-carboxamide and pharmaceutical compositions comprising the same
MALEATE, TOSILATE, FUMARATE AND OXALATE SALES OF 5- (1 (S) -AMINO-2-HYDROXYETHYL) -N - [(2,4-DIFLUOROFENIL) -METIL] -2- [8-METOXI-2- (TRIFLUOROMETIL) -5-QUINOLIN] -4-OXAZOLCARBOXAMIDA; PROCESS OF PREPARATION OF SALES, USEFUL FOR THE TREATMENT OF AFFECTIONS