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Application filed by Warner Lambert CofiledCriticalWarner Lambert Co
Priority to DO2005000151ApriorityCriticalpatent/DOP2005000151A/en
Publication of DOP2005000151ApublicationCriticalpatent/DOP2005000151A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Esta invención se refiere a compuestos de fórmula (I) en la que R1 - R8 y n se definen como en la memoria descritiva, las composiciones farmacéuticas que los contienen y su uso en el tratamiento de trastornos de sistema nervioso central.This invention relates to compounds of formula (I) in which R1-R8 and n are defined as in the specification, the pharmaceutical compositions containing them and their use in the treatment of disorders of the central nervous system.
DO2005000151A2005-08-082005-08-08
NEW INHIBITORS OF THE QUINOXALINONE NOREPINEFRINE RECAPTATION FOR THE TREATMENT OF THE CENTRAL NERVOUS SYSTEM.
DOP2005000151A
(en)
Compounds derived from 4-phenyl-4-methyl-5,6-dihydro-4h-1,3-thiazine-2-amine; pharmaceutical compositions containing them; and use of the compounds in the preparation of drugs that are inhibitors of bace, useful for the treatment of disorders mediated by this enzyme, such as Alzheimer's disease.
Compounds derived from substituted amides, inhibitors of btk activity; pharmaceutical composition comprising them; Useful in the treatment of cancer, bone disorders, autoimmune diseases, among others
A compound 8- (1,3-dihydro-isoindol-2-ylmethyl) -2,9-dihydro-1,2,7,9-tetraaza-phenalen-3-one, as a parp inhibitor; pharmaceutical composition; and its use for the treatment of cancer.
DERIVATIVES OF 2,3-DIHYDROBENZO [1,4] DIOXIN-2-ILMETILO AS ALFA2C ANTAGONISTS FOR USE IN THE TREATMENT OF CENTRAL AND PERIPHERAL NERVOUS SYSTEM DISEASES