DOP2005000095A - NEW DERIVATIVES OF AMINOPIRIDINE AND ITS USE AS PHARMACOS - Google Patents

NEW DERIVATIVES OF AMINOPIRIDINE AND ITS USE AS PHARMACOS

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Publication number
DOP2005000095A
DOP2005000095A DO2005000095A DO2005000095A DOP2005000095A DO P2005000095 A DOP2005000095 A DO P2005000095A DO 2005000095 A DO2005000095 A DO 2005000095A DO 2005000095 A DO2005000095 A DO 2005000095A DO P2005000095 A DOP2005000095 A DO P2005000095A
Authority
DO
Dominican Republic
Prior art keywords
disorders
sexual
disorder
sexual dysfunction
compounds
Prior art date
Application number
DO2005000095A
Other languages
Spanish (es)
Inventor
Duncan Charles Miller
Charlotte Moira Norforallerton
David Hepworth
Andrew Simon Cook
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority to DO2005000095A priority Critical patent/DOP2005000095A/en
Publication of DOP2005000095A publication Critical patent/DOP2005000095A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención proporciona compuestos de fórmula (I): que son una clase de agonistas de dopamina, más particularmente una clase de agonistas que son selectivos para D3 sobre D2. Estos compuestos son útiles para el tratamiento y/o prevenci6n de la disfunción sexual, por ejemplo la disfunción sexual femenina (FSD), en particular el trastorno de la excitación sexual femenina (FSAD), trastorno del deseo sexual hipoactivo (HSDD; falta de inter6s en el sexo), trastorno orgásmico femenino (FOD; incapacidad para alcanzar el orgasmo); y la disfunción sexual masculina, en particular la disfunción eréctil masculina (MED). La disfunción sexual masculina según se refiere en la presente memoria se supone que incluye trastornos eyaculatorios tales como eyaculación precoz, anorgasmia (incapacidad para alcanzar el orgasmo) o trastornos del deseo tales comp el trastorno del deseo sexual hipoactivo (HSDD; falta de interés en el sexo). Estos compuestos también son útiles para tratar trastornos neuropsiquiátricos y trastomos neurodegenerativos.The present invention provides compounds of formula (I): which are a class of dopamine agonists, more particularly a class of agonists that are selective for D3 over D2. These compounds are useful for the treatment and / or prevention of sexual dysfunction, for example female sexual dysfunction (FSD), in particular female sexual arousal disorder (FSAD), hypoactive sexual desire disorder (HSDD; lack of interest in sex), female orgasmic disorder (FOD; inability to reach orgasm); and male sexual dysfunction, in particular male erectile dysfunction (MED). Male sexual dysfunction as referred to herein is supposed to include ejaculatory disorders such as premature ejaculation, anorgasmia (inability to reach orgasm) or desire disorders such as hypoactive sexual desire disorder (HSDD; lack of interest in sex). These compounds are also useful for treating neuropsychiatric disorders and neurodegenerative disorders.

DO2005000095A 2005-05-24 2005-05-24 NEW DERIVATIVES OF AMINOPIRIDINE AND ITS USE AS PHARMACOS DOP2005000095A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DO2005000095A DOP2005000095A (en) 2005-05-24 2005-05-24 NEW DERIVATIVES OF AMINOPIRIDINE AND ITS USE AS PHARMACOS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DO2005000095A DOP2005000095A (en) 2005-05-24 2005-05-24 NEW DERIVATIVES OF AMINOPIRIDINE AND ITS USE AS PHARMACOS

Publications (1)

Publication Number Publication Date
DOP2005000095A true DOP2005000095A (en) 2005-06-14

Family

ID=44514257

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2005000095A DOP2005000095A (en) 2005-05-24 2005-05-24 NEW DERIVATIVES OF AMINOPIRIDINE AND ITS USE AS PHARMACOS

Country Status (1)

Country Link
DO (1) DOP2005000095A (en)

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