DOP2004000991A -
TIENOIMIDAZOLES REPLACED, PROCEDURE FOR THEIR PREPARATION, ITS USE AS A MEDICINAL OR DIAGNOSTIC ASSISTANT AND MEDICINAL PRODUCT THAT INCLUDES THEM
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TIENOIMIDAZOLES REPLACED, PROCEDURE FOR THEIR PREPARATION, ITS USE AS A MEDICINAL OR DIAGNOSTIC ASSISTANT AND MEDICINAL PRODUCT THAT INCLUDES THEM
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Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur
(AREA)
Abstract
Tienoimidazoles sustituidos, procedimiento para su preparación, su use como un medicamento o adyuvante de diagnóstico y medicamentos que los comprenden La invención se refiere a tienoimidazoles sustituidos de fórmula I ó II en la que Rl a R4 son cada uno como se definen en las reivindicaciones. Los medicamentos que comprenden compuestos de este tipo son útiles en la prevención o tratamiento de diversos trastornos. Por ejemplo, algunos usos de los compuestos incluyen el tratamiento de trastornos respirato rios y de ronquidos, y también para mejorar el conducto respiratorio, para tratar trastornos agudos y crónicos de los riñones y los intestinos, trastornos que resultan de acontecimientos isquémicos y/o de reperfusión y que resultan de acontecimientos proliferadores o fibróticos, el tratamiento o profilaxis de trastornos del sistema nervioso central, del metabolismo de lípidos y de la diabetes, de la coagulación sanguínea y de infestación por parásitos.Substituted thienoimidazoles, method for their preparation, their use as a medicament or diagnostic adjuvant and medicaments comprising them. The invention relates to substituted thienoimidazoles of formula I or II in which R 1 to R 4 are each as defined in the claims. Medications comprising compounds of this type are useful in the prevention or treatment of various disorders. For example, some uses of the compounds include the treatment of respiratory and snoring disorders, and also to improve the respiratory tract, to treat acute and chronic disorders of the kidneys and intestines, disorders that result from ischemic and / or reperfusion and resulting from proliferative or fibrotic events, the treatment or prophylaxis of disorders of the central nervous system, lipid metabolism and diabetes, blood clotting and parasite infestation.
DO2004000991A2004-09-062004-09-06
TIENOIMIDAZOLES REPLACED, PROCEDURE FOR THEIR PREPARATION, ITS USE AS A MEDICINAL OR DIAGNOSTIC ASSISTANT AND MEDICINAL PRODUCT THAT INCLUDES THEM
DOP2004000991A
(en)
Compounds derived from aza pyridopyrimidinone, with agonist activity of hm74a; preparation process of said compounds; pharmaceutical composition that includes them; and its use to prepare medicines for the treatment of atherosclerotic diseases, dyslipidemias, Alzheimer's, diabetes, among others.
Compounds derived from cyclohexylamine, with dual agonist activity with the m3 muscarinic receptor and agonist with the b2 adrenergic receptor; pharmaceutical composition comprising a compound; combination; pharmaceutical; and its use of a compound in the preparation of respiratory disease medication.
COMPOUNDS DERIVED FROM 1,4-BENZOTIEPIN 1,1-DIOXIDE; PHARMACEUTICAL PRODUCT; PREPARATION PROCEDURE; AND USE FOR THE TREATMENT OF LIPID METABOLISM DISORDERS, HYPERLIPIDEMIA, INSULIN RESISTANCE, SNC DIABETES AND DISORDERS, E
DERIVATIVES OF DIOSMETINE, ITS PREPARATION PROCEDURE, THE PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND THEIR USE IN THE TREATMENT OF CHRONIC VENOUS DISEASES.
METHODS TO ADMINISTER (4AR, 10AR) -1-N-PROPIL-1,2,3,4,4A, 5,10,10A-OCTAHIDRO-BENZO [G] QUINOLIN-6,7-DIOL AND RELATED COMPOUNDS THROUGH THE ORAL MUCOSA, THE NASAL MUCOSA OR THE SKIN, AND ITS PHARMACEUTICAL COMPOSITIONS
Compounds derived from 1,6-dihydro-2h-3-oxa-6-aza-as-indacene; melatonin receptor agonist; process for the preparation of compounds; pharmaceutical composition comprising the compounds; and their use of the compounds in the preparation of drugs.