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Application filed by Aventis Pharma IncfiledCriticalAventis Pharma Inc
Priority to DO2004000898ApriorityCriticalpatent/DOP2004000898A/en
Publication of DOP2004000898ApublicationCriticalpatent/DOP2004000898A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
La presente invención proporciona compuestos de la formula (I) y profármacos estéricos sales o solvatos farmacéuticasmente aceptables de compuestos de ese tipo; o profármacos estéricos de sales o solvatos de ese tipo; compasiciones farmacéutica que comprenden compuesto de ese tipo, su preparación y su uso farmacéutico en el tratamiento de estados de enfermedad que pueden modularse la inhibicion de quinasa p38 y/o factor de necrosis tumoral (TNF).The present invention provides compounds of the formula (I) and pharmaceutically acceptable steric prodrugs salts or solvates of compounds of that type; or steric prodrugs of salts or solvates of that type; Pharmaceutical compassions comprising such a compound, its preparation and its pharmaceutical use in the treatment of disease states that can be modulated by inhibition of p38 kinase and / or tumor necrosis factor (TNF).
DO2004000898A2004-05-042004-05-04
PIRAZOLES AS TUMOR NECROSIS FACTOR INHIBITORS
DOP2004000898A
(en)
Compounds derived from substituted 2,4-dianilinopyrimidines, protein kinase inhibitors; preparation procedure; pharmaceutical composition; and use for the treatment or prevention of inflammatory diseases, diabetes, and malignant tumors.
Compounds derived from 2-pyrazolamino-1,3,5-triazine, jak kinase inhibitors; preparation procedure; pharmaceutical composition; and use for the treatment of cancer.
Compounds derived from 2,4-dianilinopyrimidines, protein kinase inhibitors; preparation procedure; pharmaceutical composition; and use for the treatment or prevention of inflammatory diseases, diabetes, and cancer.