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Application filed by Elan Fharmaceuticals Inc, Pharmacia Y Up John CompanyfiledCriticalElan Fharmaceuticals Inc
Priority to DO2004000889ApriorityCriticalpatent/DOP2004000889A/en
Publication of DOP2004000889ApublicationCriticalpatent/DOP2004000889A/en
La presente invención se refiere a compuestos de la fórmula (I): útil para tratar el mal de Alzheimer y otras enfermedades similares. Estos compuestos incluyen inhibidores de la enzima beta-secretasa que son útiles para el tratamiento del mal de Alzheimer y otras enfermedades caracterizadas por la deposición de un péptido A beta en un mamifero. Los compuestos de la invención también son útiles en composiciones farmacéuticas y métodos de tratamiento para reducir la formación de un péptido A beta.The present invention relates to compounds of the formula (I): useful for treating Alzheimer's disease and other similar diseases. These compounds include beta-secretase enzyme inhibitors that are useful for the treatment of Alzheimer's disease and other diseases characterized by the deposition of a beta peptide in a mammal. The compounds of the invention are also useful in pharmaceutical compositions and treatment methods to reduce the formation of a beta A peptide.