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Priority to DO2004000842ApriorityCriticalpatent/DOP2004000842A/en
Publication of DOP2004000842ApublicationCriticalpatent/DOP2004000842A/en
La presente invención se refiere a compuestos que son inhibidores de la enzima dipeptidilpeptidasa-IV (abreviadamente en ingles "inhibidores de la DP-IV") y que son utiles en el tratamiento o prevención de enfermedades en las que este implicada la enzima dipeptidilpeptidasa-IV, tal como diabetes y particularmente diabetes tipo 2. La invención tambien se refiere a composiciones farmaceuticas que comprenden estos compuestos y el use de estos compuestos y composiciones en la prevención o tratamiento de dichas enfermedades en las que este implicada la enzima dipeptidilpeptidasa-IV.The present invention relates to compounds that are inhibitors of the enzyme dipeptidylpeptidase-IV (abbreviated in English "DP-IV inhibitors") and that are useful in the treatment or prevention of diseases in which the enzyme dipeptidylpeptidase-IV is involved , such as diabetes and particularly type 2 diabetes. The invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of said diseases in which the enzyme dipeptidylpeptidase-IV is involved.
DO2004000842A2004-03-052004-03-05
INHIBITORS OF THE BETA-AMINO HETEROCICLICO DIPEPTIDIL PEPTIDASA FOR THE TREATMENT OR PREVENTION OF DIABETES
DOP2004000842A
(en)
Compounds derived from bi-, tri or non-aromatic polycycles, inhibitors of the 11-beta-hydroxysteroid dehydrogenase enzyme type i; process of preparation of these; pharmaceutical composition that includes them; use in the treatment of diseases such as obesity, diabetes and dyslipidemia, among others.
at least one chemical entity, pharmaceutical composition, methods for treating a patient, inhibiting at least one enzyme using atp, and treating at least one disease, use of at least one chemical entity, and method for the manufacture of a medicament
Compound derived from 2-arylamino-4-aminopyrimidines, c-alpha protein kinase inhibitors; pharmaceutical compositions containing them; and its use to treat or prevent diabetes, cancer, cardiovascular diseases and others.