DOP2003000770A - INDOLES WITH ANTIBIABETIC ACTIVITY - Google Patents

INDOLES WITH ANTIBIABETIC ACTIVITY

Info

Publication number
DOP2003000770A
DOP2003000770A DO2003000770A DO2003000770A DOP2003000770A DO P2003000770 A DOP2003000770 A DO P2003000770A DO 2003000770 A DO2003000770 A DO 2003000770A DO 2003000770 A DO2003000770 A DO 2003000770A DO P2003000770 A DOP2003000770 A DO P2003000770A
Authority
DO
Dominican Republic
Prior art keywords
indoles
antibiabetic
activity
diabetes
type
Prior art date
Application number
DO2003000770A
Other languages
Spanish (es)
Inventor
John J Acton Iii
Sheryl D Debenham
Kun Liu
Peter T Meinke
Harold B Wood
Regina M Black
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Priority to DO2003000770A priority Critical patent/DOP2003000770A/en
Publication of DOP2003000770A publication Critical patent/DOP2003000770A/en

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  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Indoles having aryloxyalkanoic acid substituents or arylalkanoic acid substituents are agonists or partial agonists of PPAR gamma and are useful in the treatment and control of hyperglycemia that is symptomatic of type II diabetes, as well as dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity that are often associated with type 2 diabetes.Indoles having aryloxyalkanoic acid substituents or arylalkanoic acid substituents are agonists or partial agonists of PPAR gamma and are useful in the treatment and control of hyperglycemia that is symptomatic of type II diabetes, as well as dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity often associated with type 2 diabetes.

DO2003000770A 2003-12-01 2003-12-01 INDOLES WITH ANTIBIABETIC ACTIVITY DOP2003000770A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DO2003000770A DOP2003000770A (en) 2003-12-01 2003-12-01 INDOLES WITH ANTIBIABETIC ACTIVITY

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DO2003000770A DOP2003000770A (en) 2003-12-01 2003-12-01 INDOLES WITH ANTIBIABETIC ACTIVITY

Publications (1)

Publication Number Publication Date
DOP2003000770A true DOP2003000770A (en) 2004-07-15

Family

ID=44261260

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2003000770A DOP2003000770A (en) 2003-12-01 2003-12-01 INDOLES WITH ANTIBIABETIC ACTIVITY

Country Status (1)

Country Link
DO (1) DOP2003000770A (en)

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