DK75985A - PROCEDURE FOR THE PREPARATION OF AN ETHENDIAMIN DERIVATIVE - Google Patents

PROCEDURE FOR THE PREPARATION OF AN ETHENDIAMIN DERIVATIVE Download PDF

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Publication number
DK75985A
DK75985A DK75985A DK75985A DK75985A DK 75985 A DK75985 A DK 75985A DK 75985 A DK75985 A DK 75985A DK 75985 A DK75985 A DK 75985A DK 75985 A DK75985 A DK 75985A
Authority
DK
Denmark
Prior art keywords
methylenedioxybenzyl
methyl
ethendiamin
derivative
procedure
Prior art date
Application number
DK75985A
Other languages
Danish (da)
Other versions
DK157494B (en
DK75985D0 (en
DK157494C (en
Inventor
Leonardo De Vincentiis
Original Assignee
Ausonia Farma Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ausonia Farma Srl filed Critical Ausonia Farma Srl
Publication of DK75985D0 publication Critical patent/DK75985D0/en
Publication of DK75985A publication Critical patent/DK75985A/en
Publication of DK157494B publication Critical patent/DK157494B/en
Application granted granted Critical
Publication of DK157494C publication Critical patent/DK157494C/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

N-[2-[[[5-[(Dimethylamino)methyl]-2-furanyl]methyl]thio] ethyl]-N'-(3,4-methylenedioxybenzyl)-2-nitro-1,1- ethenediamine of the formula: <IMAGE> which has antiulcer activity, is prepared in high yield and at high purity by reacting 2-(dimethylaminomethyl)-5- (R-methyl)furan, where R is hydroxyl, halogen, dimethylamino or trimethylammonium iodide, with 1-nitro-2- (3,4-methylenedioxybenzyl)-2-(2-mercaptoethyl) ethenediamine; or with N-(2-mercaptoethyl)-N'-(3,4- methylenedioxybenzyl)urea or -thiourea and subsequently reacting the resulting intermediate with nitromethane; or else by condensing 2-(dimethylaminomethyl)-5-(2- hydroxy)ethylthiomethylfuran with 2-amino-2-(3,4- methylenedioxybenzylamino)-1-nitroethene.
DK075985A 1984-03-07 1985-02-19 METHOD FOR PREPARING N- (2 (((5 - ((DIMETHYLAMINO) -METHYL) -2-FURANYL) METHYL) THIO) ETHYL) -N '(3,4-METHYLENDIOXYBENZYL) -2-NITRO-1,1- ethenediamine DK157494C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT19929/84A IT1175808B (en) 1984-03-07 1984-03-07 PROCEDURE FOR THE PREPARATION OF COMPOUND WITH ANTI-ULTER ACTIVITY
IT1992984 1984-03-07

Publications (4)

Publication Number Publication Date
DK75985D0 DK75985D0 (en) 1985-02-19
DK75985A true DK75985A (en) 1985-09-08
DK157494B DK157494B (en) 1990-01-15
DK157494C DK157494C (en) 1990-06-11

Family

ID=11162427

Family Applications (1)

Application Number Title Priority Date Filing Date
DK075985A DK157494C (en) 1984-03-07 1985-02-19 METHOD FOR PREPARING N- (2 (((5 - ((DIMETHYLAMINO) -METHYL) -2-FURANYL) METHYL) THIO) ETHYL) -N '(3,4-METHYLENDIOXYBENZYL) -2-NITRO-1,1- ethenediamine

Country Status (12)

Country Link
KR (1) KR870000922B1 (en)
AR (1) AR242955A1 (en)
AT (1) AT384610B (en)
CA (1) CA1227492A (en)
DK (1) DK157494C (en)
ES (1) ES8607291A1 (en)
FI (1) FI850554L (en)
GR (1) GR850398B (en)
IT (1) IT1175808B (en)
NO (1) NO850897L (en)
PT (1) PT80066B (en)
ZA (1) ZA851296B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110294696B (en) * 2018-03-24 2021-07-02 复旦大学 Thioethylurea/thiourea dimer derivatives, preparation method and medicinal application thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1168163B (en) * 1981-08-18 1987-05-20 Ausonia Farma Srl COMPOUND WITH ANTI-ULTER ACTIVITY, PROCEDURE FOR ITS PREPARATION AND RELATIVE PHARMACEUTICAL COMPOSITIONS

Also Published As

Publication number Publication date
DK157494B (en) 1990-01-15
KR850006409A (en) 1985-10-05
DK75985D0 (en) 1985-02-19
NO850897L (en) 1985-09-09
IT1175808B (en) 1987-07-15
FI850554A0 (en) 1985-02-11
ATA43385A (en) 1987-05-15
ES8607291A1 (en) 1986-05-16
FI850554L (en) 1985-09-08
AR242955A1 (en) 1993-06-30
PT80066A (en) 1985-04-01
CA1227492A (en) 1987-09-29
AT384610B (en) 1987-12-10
KR870000922B1 (en) 1987-05-07
GR850398B (en) 1985-06-14
ZA851296B (en) 1985-10-30
IT8419929A0 (en) 1984-03-07
ES540987A0 (en) 1986-05-16
PT80066B (en) 1987-09-30
DK157494C (en) 1990-06-11

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