DK703588A - PAI-1 BLOCKING PEPTIDES, THEIR PREPARATION AND USE - Google Patents

PAI-1 BLOCKING PEPTIDES, THEIR PREPARATION AND USE

Info

Publication number
DK703588A
DK703588A DK703588A DK703588A DK703588A DK 703588 A DK703588 A DK 703588A DK 703588 A DK703588 A DK 703588A DK 703588 A DK703588 A DK 703588A DK 703588 A DK703588 A DK 703588A
Authority
DK
Denmark
Prior art keywords
pai
preparation
blocking peptides
peptides
blocking
Prior art date
Application number
DK703588A
Other languages
Danish (da)
Other versions
DK703588D0 (en
Inventor
Thomas Stief
Werner Stueber
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of DK703588D0 publication Critical patent/DK703588D0/en
Publication of DK703588A publication Critical patent/DK703588A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8132—Plasminogen activator inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/38—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against protease inhibitors of peptide structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK703588A 1987-12-18 1988-12-16 PAI-1 BLOCKING PEPTIDES, THEIR PREPARATION AND USE DK703588A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873742997 DE3742997A1 (en) 1987-12-18 1987-12-18 PEPTIDES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE FOR THE OBTAINING OF ANTIBODIES, AND THEIR USE FOR BLOCKING THE PAI-1 ACTIVITY OF HUMAN BLOOD

Publications (2)

Publication Number Publication Date
DK703588D0 DK703588D0 (en) 1988-12-16
DK703588A true DK703588A (en) 1989-06-19

Family

ID=6342939

Family Applications (1)

Application Number Title Priority Date Filing Date
DK703588A DK703588A (en) 1987-12-18 1988-12-16 PAI-1 BLOCKING PEPTIDES, THEIR PREPARATION AND USE

Country Status (8)

Country Link
EP (1) EP0320840A3 (en)
JP (1) JPH01199996A (en)
KR (1) KR890009972A (en)
AU (1) AU634955B2 (en)
DE (1) DE3742997A1 (en)
DK (1) DK703588A (en)
FI (1) FI885797A (en)
PT (1) PT89224B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999020295A1 (en) * 1997-10-17 1999-04-29 Trustees Of The University Of Pennsylvania Compositions and methods for promoting internalization and degradation of urokinase-type plasminogen activator
US6750201B1 (en) 1997-10-17 2004-06-15 The Trustees Of The University Of Pennsylvania Compositions and methods for promoting internalization and degradation of urokinase-type plasminogen activator
US6767540B2 (en) * 2000-01-14 2004-07-27 Tanox, Inc. Use of antagonists of plasminogen activator inhibitor-1 (PAI-1) for the treatment of asthma and chronic obstructive pulmonary disease
WO2011139974A2 (en) * 2010-05-03 2011-11-10 Abbott Laboratories Anti-pai-1 antibodies and methods of use thereof
EP3109320B1 (en) * 2014-02-21 2019-03-27 Astellas Pharma Inc. New anti-human pai-1 antibody

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4923807A (en) * 1984-05-18 1990-05-08 New England Medical Center Hospitals Inc. Arg-Serpin human plasminogen activator inhibitor designated PAI-2
DK319685A (en) * 1985-07-12 1987-01-13 Fonden Til Fremme Af Eksperime MONOCLONAL ANTIBODIES, PROCEDURES FOR PRODUCING ANTIBODIES, HYBRIDOMA CELLS PRODUCING ANTIBODIES, AND USING ANTIBODIES
JPH04505252A (en) * 1989-05-11 1992-09-17 イー・アイ・デュポン・ドゥ・ヌムール・アンド・カンパニー E. High level expression of functional human plasminogen activator inhibitor (PAI-1) in E. coli
NL8902454A (en) * 1989-10-03 1991-05-01 Stichting Centraal Lab MUTANTS OF THE HUMANE PLASMINOGENIC ACTIVATOR INHIBITOR 1 (PAI-1), THEIR PREPARATION AND USE, AND RECOMBINANT POLYNUCLEOTIDES INCLUDING GENETIC INFORMATION CODING FOR THESE MUTANTS.

Also Published As

Publication number Publication date
FI885797A0 (en) 1988-12-15
JPH01199996A (en) 1989-08-11
DK703588D0 (en) 1988-12-16
EP0320840A2 (en) 1989-06-21
PT89224B (en) 1993-07-30
KR890009972A (en) 1989-08-05
AU634955B2 (en) 1993-03-11
PT89224A (en) 1989-12-29
AU2695588A (en) 1989-06-22
DE3742997A1 (en) 1989-06-29
FI885797A (en) 1989-06-19
EP0320840A3 (en) 1990-04-25

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Legal Events

Date Code Title Description
ATS Application withdrawn