DK639988A - Aminoterminalt tryptisk fragment af glycocalicin og anvendelse deraf til inhibering af blodpladeaggregering - Google Patents

Aminoterminalt tryptisk fragment af glycocalicin og anvendelse deraf til inhibering af blodpladeaggregering

Info

Publication number
DK639988A
DK639988A DK639988A DK639988A DK639988A DK 639988 A DK639988 A DK 639988A DK 639988 A DK639988 A DK 639988A DK 639988 A DK639988 A DK 639988A DK 639988 A DK639988 A DK 639988A
Authority
DK
Denmark
Prior art keywords
glycocalicin
aminoterminal
platelet aggregation
inhibit platelet
tryptic fragment
Prior art date
Application number
DK639988A
Other languages
Danish (da)
English (en)
Other versions
DK639988D0 (da
Inventor
Theodore S Zimmerman
Zaverio M Ruggeri
Richard A Houghten
Vicente Vicente
Hiroshi Mohri
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Publication of DK639988D0 publication Critical patent/DK639988D0/da
Publication of DK639988A publication Critical patent/DK639988A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK639988A 1987-11-17 1988-11-16 Aminoterminalt tryptisk fragment af glycocalicin og anvendelse deraf til inhibering af blodpladeaggregering DK639988A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12145487A 1987-11-17 1987-11-17

Publications (2)

Publication Number Publication Date
DK639988D0 DK639988D0 (da) 1988-11-16
DK639988A true DK639988A (da) 1989-05-18

Family

ID=22396842

Family Applications (1)

Application Number Title Priority Date Filing Date
DK639988A DK639988A (da) 1987-11-17 1988-11-16 Aminoterminalt tryptisk fragment af glycocalicin og anvendelse deraf til inhibering af blodpladeaggregering

Country Status (9)

Country Link
EP (1) EP0317278A3 (de)
JP (1) JPH01221394A (de)
KR (1) KR890008169A (de)
AU (1) AU626813B2 (de)
DK (1) DK639988A (de)
FI (1) FI885303A (de)
IL (1) IL88308A0 (de)
NO (1) NO885108L (de)
NZ (1) NZ226964A (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5340727A (en) * 1987-11-17 1994-08-23 The Scripps Research Institute GPIbα fragments and recombinant DNA expression vectors
US5332726A (en) * 1989-09-29 1994-07-26 Rhone-Poulenc Rorer Pharmaceuticals Inc. Antithrombotic peptides and pseudopeptides
ES2097765T3 (es) * 1989-10-20 1997-04-16 New England Medical Center Inc Un sistema de inhibicion del enlazado de celulas intermediado por padgem.
US6008193A (en) * 1990-03-02 1999-12-28 Bio-Technology General Corp. Methods of using human von Willebrand factor GPIb binding domain polypeptides
US5849536A (en) * 1990-03-02 1998-12-15 Bio-Technology General Corp. Cloning and production of human von willebrand factor GPIb binding domain polypeptides and methods of using same
US5064814A (en) * 1990-04-05 1991-11-12 Rhone-Poulenc Rorer Pharmaceuticals Inc. Anti-thrombotic peptide and pseudopeptide derivatives
US5342830A (en) * 1990-11-16 1994-08-30 Cor Therapeutics, Inc. Antithrombosis agents
US5317097A (en) * 1991-10-07 1994-05-31 The Research Foundation Of State University Of New York Mutations in the gene encoding the α chain on platelet glycoprotein IB
US5298239A (en) * 1991-10-07 1994-03-29 The Research Foundation Of State University Of New York Mutations rendering platelet glycoprotein IB α less reactive
US5427939A (en) * 1992-01-06 1995-06-27 The Scripps Research Institute Expression vectors encoding alloantigens of glycoprotein Ibα
WO1993016712A1 (en) * 1992-02-26 1993-09-02 The Scripps Research Institute MUTANT GPIbα FRAGMENTS AND RECOMBINANT EXPRESSION THEREOF
AR035779A1 (es) 2001-02-06 2004-07-14 Genetics Inst Llc Polipeptidos de fusion derivados de glicoproteina ib alfa de plaqueta y metodos de uso de los mismos
EP2522677A1 (de) * 2003-06-11 2012-11-14 Wyeth LLC Fusionspolypeptide des Platelet Glycoprotein IB alpha Variant und Verfahren zu deren Anwendung
CN101389356B (zh) 2006-01-06 2012-09-05 武冈真司 药物输送物质
DE102007031708A1 (de) 2007-07-06 2009-01-08 Dade Behring Marburg Gmbh Bestimmung der von Willebrand Faktor-Aktivität in Abwesenheit von Ristocetin

Also Published As

Publication number Publication date
DK639988D0 (da) 1988-11-16
NO885108D0 (no) 1988-11-16
IL88308A0 (en) 1989-06-30
AU2560588A (en) 1989-05-18
KR890008169A (ko) 1989-07-10
JPH01221394A (ja) 1989-09-04
NO885108L (no) 1989-05-18
NZ226964A (en) 1991-08-27
FI885303A0 (fi) 1988-11-16
EP0317278A2 (de) 1989-05-24
FI885303A (fi) 1989-05-18
AU626813B2 (en) 1992-08-13
EP0317278A3 (de) 1989-11-23

Similar Documents

Publication Publication Date Title
DK639988A (da) Aminoterminalt tryptisk fragment af glycocalicin og anvendelse deraf til inhibering af blodpladeaggregering
DK248885A (da) Middel til bekaempelse af helmintiske arthropode ektoparasitiske og acaridale infektioner
IT1173724B (it) Derivati della piperidina,loro preparazione e loro impiego come medicamenti
IT1204696B (it) Procedimento e dispositivo per produrre due filoni continui di sigarette
IT1219941B (it) Composizioni farmaceutiche contenenenti cefuroxima axetil e procedimento per prepararle
IT1179367B (it) Composizioni farmaceutiche contenenti ranitidina e procedimento per prepararle
DK589086D0 (da) Farmaceutisk sustained release praeparat indeholdende dextromethorphansamt dets fremstilling og anvendelse
DK188488D0 (da) Benzen-derivater med leukotrien-antagonistvirkning og fremgangsmaade til fremstilling af saadanne derivater
IT1177375B (it) Composizione e procedimento per inibire le incrostazioni
DK210690D0 (da) Metoder og praeparater til inhibering af blodpladeaggregation
JPS521009A (en) Composition of agglutination of blood platelet
DK689987D0 (da) Forbindelser med uv-absorberende egenskaber og formuleringer med solfiltervirkning indeholdende saadanne forbindelser
KR880701524A (ko) 1-옥소히드로카르빌-치환 아자시클로헥산으로 되는 조성물 및 그의 용도
TR22145A (tr) Hidroksi-4-2h-1-benzotiopiron-2-one tuerevleri bunlarin hazirlanmasi ve kullanilmasi
IT1203738B (it) Bilirubin-cssidasi termostabile e procedimento per produrla
DK162686A (da) Pseudopterosin og syntetisk derivater deraf og forbindelsernes anvendelse
IT8448415A0 (it) Derivati della 1,4-diidropiridina, loro preparazione e loro impiego come medicamenti
IT8822760A0 (it) Ciclodestrinclatrati di derivati della 5-ciano-prostaciclina e loro impiego come medicinali
IT8348488A0 (it) Derivati della 1,4-diidropiridina, loro preparazione e loro impiego come medicamenti
IT8647524A0 (it) Derivati fosforilalcanolammidici della l-carnitina e composizioni farmaceutiche che li contengono
IT8449056A1 (it) Derivati dell' 1- 2 ditiolano loro preparazione e loro impiego come medicamenti
DK169481A (da) Kobberphthalocyaninpigmenter deres fremstilling og deres anvendelse
IT1227456B (it) Nuovi alcossi derivati di ginkgolidi, loro preparazione e composizioni terapeutiche che li contengono
DK64688A (da) Nukleotidanaloger og fremstilling og anvendelse deraf
ATA588977A (de) Aus spreizduebel und befestigungsschraube bestehender befestigungssatz

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment