DK573487A - CYCLODEXTRINCLATHRATES OF CARBACYCLININE DERIVATIVES AND USE THEREOF AS A MEDICINE - Google Patents
CYCLODEXTRINCLATHRATES OF CARBACYCLININE DERIVATIVES AND USE THEREOF AS A MEDICINEInfo
- Publication number
- DK573487A DK573487A DK573487A DK573487A DK573487A DK 573487 A DK573487 A DK 573487A DK 573487 A DK573487 A DK 573487A DK 573487 A DK573487 A DK 573487A DK 573487 A DK573487 A DK 573487A
- Authority
- DK
- Denmark
- Prior art keywords
- group
- atoms
- image
- straight
- chain
- Prior art date
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- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
Cyclodextrin clathrates of carbacyclin analogues having the general formula I <IMAGE> in which R1 is a hydrogen atom or a straight-chain or branched alkyl group having up to 10 C atoms, A is a trans-CH=CH- or a -C<IMAGE>C-group, W is a free or functionally altered hydroxymethylene group or a free or functionally altered <IMAGE> group in which the OH group can be in the α position or the β position, D is the group <IMAGE> a straight-chain, saturated alklene group having 1-5 C atoms, a branched or straight-chain or branched, unsaturated alkylene group having 2-5 C atoms which can optionally be substituted by fluorine atoms, m is the number 1, 2 or 3, E is a direct linkage, a -C=C- group or -CR4=CR5- group, in which R4 is hydrogen or an alkyl group having 1-5 C atoms, and R5 is hydrogen, halogen or an alkyl group having 1-5 C atoms, R2 is an alkyl group having 1-10 C atoms, a cycloalkyl group having 3-10 C atoms or an optionally substituted aryl group having 6-10 C atoms or a heterocyclic group, and R3 is a free or functionally changed hydroxyl group, n is the number 1, 2, 3, 4 or 5, and X is a CH2 group or an oxygen atom together with pharmaceutically acceptable carrier substances and auxiliary substances.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3608088 | 1986-03-07 | ||
DE3608088A DE3608088C2 (en) | 1986-03-07 | 1986-03-07 | Pharmaceutical preparations containing cyclodextrin clathrates of carbacyclin derivatives |
DE8700106 | 1987-03-09 | ||
PCT/DE1987/000106 WO1987005294A1 (en) | 1986-03-07 | 1987-03-09 | Cyclodextrinclathrates of carbacycline derivatives and their use as medicinal drugs |
Publications (3)
Publication Number | Publication Date |
---|---|
DK573487A true DK573487A (en) | 1987-11-02 |
DK573487D0 DK573487D0 (en) | 1987-11-02 |
DK169432B1 DK169432B1 (en) | 1994-10-31 |
Family
ID=25841830
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK573487A DK169432B1 (en) | 1986-03-07 | 1987-11-02 | Cyclodextrin clathrates of carbacyclin derivatives |
Country Status (1)
Country | Link |
---|---|
DK (1) | DK169432B1 (en) |
-
1987
- 1987-11-02 DK DK573487A patent/DK169432B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DK169432B1 (en) | 1994-10-31 |
DK573487D0 (en) | 1987-11-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PUP | Patent expired |