DK535982A - 9-brom-prostaglandinderivater, fremgangsmaade til deres fremstilling og deres anvendelse som laegemiddel - Google Patents
9-brom-prostaglandinderivater, fremgangsmaade til deres fremstilling og deres anvendelse som laegemiddel Download PDFInfo
- Publication number
- DK535982A DK535982A DK535982A DK535982A DK535982A DK 535982 A DK535982 A DK 535982A DK 535982 A DK535982 A DK 535982A DK 535982 A DK535982 A DK 535982A DK 535982 A DK535982 A DK 535982A
- Authority
- DK
- Denmark
- Prior art keywords
- hydrogen
- alkyl
- free
- group
- functionally modified
- Prior art date
Links
- 239000004615 ingredient Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 101100294106 Caenorhabditis elegans nhr-3 gene Proteins 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000004015 abortifacient agent Substances 0.000 abstract 1
- 231100000641 abortifacient agent Toxicity 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical group O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
- -1 hydroxymethylene group Chemical class 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrane Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3148743 | 1981-12-04 | ||
| DE19813148743 DE3148743A1 (de) | 1981-12-04 | 1981-12-04 | 9-brom-prostaglandinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK535982A true DK535982A (da) | 1983-06-05 |
| DK153785B DK153785B (da) | 1988-09-05 |
| DK153785C DK153785C (da) | 1989-06-12 |
Family
ID=6148278
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK535982A DK153785C (da) | 1981-12-04 | 1982-12-02 | Analogifremgangsmaade til fremstilling af 9-brom-prostanderivater. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4487953A (da) |
| EP (1) | EP0081455B1 (da) |
| JP (1) | JPS58121268A (da) |
| AT (1) | ATE19064T1 (da) |
| AU (1) | AU561813B2 (da) |
| CA (1) | CA1223871A (da) |
| DE (2) | DE3148743A1 (da) |
| DK (1) | DK153785C (da) |
| ES (1) | ES8307740A1 (da) |
| GR (1) | GR77770B (da) |
| HU (1) | HU190823B (da) |
| IE (1) | IE54349B1 (da) |
| IL (1) | IL67402A (da) |
| SU (1) | SU1225486A3 (da) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3997587A (en) * | 1975-06-26 | 1976-12-14 | Syntex (U.S.A.) Inc. | D1- and 8R-9-fluoro-prostadienoic acid derivatives |
| US4156087A (en) * | 1977-04-11 | 1979-05-22 | The Upjohn Company | 9-Deoxy-16,16-dimethyl-PGF2 compounds |
| DE2950027A1 (de) * | 1979-12-10 | 1981-06-11 | Schering Ag Berlin Und Bergkamen, 1000 Berlin | 9-chlor-prostaglandinderivate, verfahren zur herstellung und verwendung als arzneimittel |
-
1981
- 1981-12-04 DE DE19813148743 patent/DE3148743A1/de not_active Withdrawn
-
1982
- 1982-11-18 AU AU90705/82A patent/AU561813B2/en not_active Ceased
- 1982-11-30 SU SU823515436A patent/SU1225486A3/ru active
- 1982-12-02 DK DK535982A patent/DK153785C/da active
- 1982-12-02 GR GR69969A patent/GR77770B/el unknown
- 1982-12-03 HU HU823889A patent/HU190823B/hu unknown
- 1982-12-03 CA CA000416964A patent/CA1223871A/en not_active Expired
- 1982-12-03 DE DE8282730142T patent/DE3270496D1/de not_active Expired
- 1982-12-03 AT AT82730142T patent/ATE19064T1/de not_active IP Right Cessation
- 1982-12-03 IL IL67402A patent/IL67402A/xx not_active IP Right Cessation
- 1982-12-03 JP JP57212615A patent/JPS58121268A/ja active Pending
- 1982-12-03 ES ES517915A patent/ES8307740A1/es not_active Expired
- 1982-12-03 EP EP82730142A patent/EP0081455B1/de not_active Expired
- 1982-12-06 IE IE2881/82A patent/IE54349B1/en not_active IP Right Cessation
- 1982-12-06 US US06/446,888 patent/US4487953A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| SU1225486A3 (ru) | 1986-04-15 |
| DK153785B (da) | 1988-09-05 |
| DE3270496D1 (en) | 1986-05-15 |
| ES517915A0 (es) | 1983-08-16 |
| AU9070582A (en) | 1983-06-09 |
| IE54349B1 (en) | 1989-08-30 |
| US4487953A (en) | 1984-12-11 |
| ES8307740A1 (es) | 1983-08-16 |
| DE3148743A1 (de) | 1983-06-09 |
| GR77770B (da) | 1984-09-25 |
| JPS58121268A (ja) | 1983-07-19 |
| IE822881L (en) | 1983-06-04 |
| EP0081455B1 (de) | 1986-04-09 |
| EP0081455A2 (de) | 1983-06-15 |
| DK153785C (da) | 1989-06-12 |
| AU561813B2 (en) | 1987-05-21 |
| EP0081455A3 (en) | 1983-08-03 |
| CA1223871A (en) | 1987-07-07 |
| HU190823B (en) | 1986-11-28 |
| ATE19064T1 (de) | 1986-04-15 |
| IL67402A (en) | 1986-04-29 |
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