DK53290A - SYNTHETIC GAER LEADER PEPTIDES - Google Patents

SYNTHETIC GAER LEADER PEPTIDES Download PDF

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Publication number
DK53290A
DK53290A DK053290A DK53290A DK53290A DK 53290 A DK53290 A DK 53290A DK 053290 A DK053290 A DK 053290A DK 53290 A DK53290 A DK 53290A DK 53290 A DK53290 A DK 53290A
Authority
DK
Denmark
Prior art keywords
glu
synthetic
thr
ala
ser
Prior art date
Application number
DK053290A
Other languages
Danish (da)
Other versions
DK53290D0 (en
DK164874C (en
DK164874B (en
Inventor
Lars Christiansen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK463887A external-priority patent/DK463887D0/en
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Priority to DK053290A priority Critical patent/DK164874C/en
Publication of DK53290D0 publication Critical patent/DK53290D0/en
Publication of DK53290A publication Critical patent/DK53290A/en
Publication of DK164874B publication Critical patent/DK164874B/en
Application granted granted Critical
Publication of DK164874C publication Critical patent/DK164874C/en

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Synthetic leader peptides for efficient secretion of proteins in yeast have the general formula I X1-Pro-Val-Thr-Gly-Asp-Glu-Ser-Ser-Val-Glu-Ila-Pro-(Glu- Glu-Ser-Leu-Ile)n-X2-Ala-Glu-Asn-Thr-Thr-Leu-Ala-X3-X4-X5 characterized in that X1 is Ala or Gln; X2 is Ile, a peptide chain having up to 10 amino acid residues or a peptide bond; X3 is a peptide chain having up to 5 amino acid residues or a peptide bond, X4 and X5 are Lys or Arg; and n is 1 or 0. <IMAGE>
DK053290A 1987-09-07 1990-03-01 SYNTHETIC YEAR LEADER PEPTIDES, DNA SEQUENCE, WHICH ENCODES SUCH LEADER PEPTIDES, VECTORS AND TRANSFORMED YARN STEMS, AND A PROCEDURE FOR YEAR PROTEIN MANUFACTURING DK164874C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK053290A DK164874C (en) 1987-09-07 1990-03-01 SYNTHETIC YEAR LEADER PEPTIDES, DNA SEQUENCE, WHICH ENCODES SUCH LEADER PEPTIDES, VECTORS AND TRANSFORMED YARN STEMS, AND A PROCEDURE FOR YEAR PROTEIN MANUFACTURING

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DK463887 1987-09-07
DK463887A DK463887D0 (en) 1987-09-07 1987-09-07 GAERLEADER
PCT/DK1988/000147 WO1989002463A1 (en) 1987-09-07 1988-09-06 Synthetic yeast leader peptides
DK8800147 1988-09-06
DK053290A DK164874C (en) 1987-09-07 1990-03-01 SYNTHETIC YEAR LEADER PEPTIDES, DNA SEQUENCE, WHICH ENCODES SUCH LEADER PEPTIDES, VECTORS AND TRANSFORMED YARN STEMS, AND A PROCEDURE FOR YEAR PROTEIN MANUFACTURING
DK53290 1990-03-01

Publications (4)

Publication Number Publication Date
DK53290D0 DK53290D0 (en) 1990-03-01
DK53290A true DK53290A (en) 1990-03-01
DK164874B DK164874B (en) 1992-08-31
DK164874C DK164874C (en) 1993-01-11

Family

ID=26064171

Family Applications (1)

Application Number Title Priority Date Filing Date
DK053290A DK164874C (en) 1987-09-07 1990-03-01 SYNTHETIC YEAR LEADER PEPTIDES, DNA SEQUENCE, WHICH ENCODES SUCH LEADER PEPTIDES, VECTORS AND TRANSFORMED YARN STEMS, AND A PROCEDURE FOR YEAR PROTEIN MANUFACTURING

Country Status (1)

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DK (1) DK164874C (en)

Also Published As

Publication number Publication date
DK53290D0 (en) 1990-03-01
DK164874C (en) 1993-01-11
DK164874B (en) 1992-08-31

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