DK451184A - 3-alkyl-7-halogen-2,3-dihydro-spiro(naphthalen-1(4h), 3'-pyrrolidin)-2',4,5'-trioner og farmaceutiske praeparater indeholdende disse - Google Patents

3-alkyl-7-halogen-2,3-dihydro-spiro(naphthalen-1(4h), 3'-pyrrolidin)-2',4,5'-trioner og farmaceutiske praeparater indeholdende disse Download PDF

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Publication number
DK451184A
DK451184A DK451184A DK451184A DK451184A DK 451184 A DK451184 A DK 451184A DK 451184 A DK451184 A DK 451184A DK 451184 A DK451184 A DK 451184A DK 451184 A DK451184 A DK 451184A
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DK
Denmark
Prior art keywords
spiro
triones
naphthalen
pyrrolidin
dihydro
Prior art date
Application number
DK451184A
Other languages
English (en)
Other versions
DK451184D0 (da
Inventor
Christopher Andrew Lipinski
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK451184D0 publication Critical patent/DK451184D0/da
Publication of DK451184A publication Critical patent/DK451184A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/96—Spiro-condensed ring systems

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Indole Compounds (AREA)
DK451184A 1983-09-23 1984-09-21 3-alkyl-7-halogen-2,3-dihydro-spiro(naphthalen-1(4h), 3'-pyrrolidin)-2',4,5'-trioner og farmaceutiske praeparater indeholdende disse DK451184A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53544483A 1983-09-23 1983-09-23

Publications (2)

Publication Number Publication Date
DK451184D0 DK451184D0 (da) 1984-09-21
DK451184A true DK451184A (da) 1985-03-24

Family

ID=24134256

Family Applications (1)

Application Number Title Priority Date Filing Date
DK451184A DK451184A (da) 1983-09-23 1984-09-21 3-alkyl-7-halogen-2,3-dihydro-spiro(naphthalen-1(4h), 3'-pyrrolidin)-2',4,5'-trioner og farmaceutiske praeparater indeholdende disse

Country Status (6)

Country Link
EP (1) EP0136143B1 (da)
JP (1) JPS6092264A (da)
AT (1) ATE30585T1 (da)
DE (1) DE3467166D1 (da)
DK (1) DK451184A (da)
GR (1) GR80428B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3670570D1 (de) * 1986-09-02 1990-05-31 Alcon Lab Inc Aldose-reductase-hemmer, nuetzlich bei der behandlung von glaukom.
US4900739A (en) * 1988-10-20 1990-02-13 American Home Products Corp. Novel spirosuccinimides as aldose reductase inhibitors and antihyperglycemic agents
US4946858A (en) * 1988-10-20 1990-08-07 American Home Products Corporation Novel spirosuccinimides as aldose reductase inhibitors and antihyperglycemic agents
US5039672A (en) * 1990-04-05 1991-08-13 Pfizer Inc. Heterocyclic compounds as aldose reductase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985888A (en) * 1969-07-24 1976-10-12 Richardson-Merrell Inc. Methods of inducing sedation using certain spiroalkanone-imides
US4117230A (en) * 1976-10-18 1978-09-26 Pfizer Inc. Hydantoin derivatives as therapeutic agents
US4307108A (en) * 1979-12-26 1981-12-22 Pfizer Inc. Method for lowering sorbitol levels using spiro-imides
DE3262294D1 (en) * 1981-05-13 1985-03-28 Ici Plc Pharmaceutical compositions containing spiro succinimide derivatives

Also Published As

Publication number Publication date
ATE30585T1 (de) 1987-11-15
EP0136143A3 (en) 1985-05-15
EP0136143A2 (en) 1985-04-03
DK451184D0 (da) 1984-09-21
EP0136143B1 (en) 1987-11-04
DE3467166D1 (en) 1987-12-10
GR80428B (en) 1985-01-22
JPS6092264A (ja) 1985-05-23

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Legal Events

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AHS Application shelved for other reasons than non-payment