DK44386A - 6-chlor-3-methyl-1h-2,3,4,5-tetra-hydro-3-benzazepin-n-oxid og laegemidler, hvori det anvendes - Google Patents

6-chlor-3-methyl-1h-2,3,4,5-tetra-hydro-3-benzazepin-n-oxid og laegemidler, hvori det anvendes Download PDF

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Publication number
DK44386A
DK44386A DK44386A DK44386A DK44386A DK 44386 A DK44386 A DK 44386A DK 44386 A DK44386 A DK 44386A DK 44386 A DK44386 A DK 44386A DK 44386 A DK44386 A DK 44386A
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DK
Denmark
Prior art keywords
benzazepine
chlor
hydro
tetra
methyl
Prior art date
Application number
DK44386A
Other languages
English (en)
Other versions
DK44386D0 (da
Inventor
Robert Michael Demarinis
Kenneth Marshall Straub
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of DK44386D0 publication Critical patent/DK44386D0/da
Publication of DK44386A publication Critical patent/DK44386A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
DK44386A 1985-01-30 1986-01-29 6-chlor-3-methyl-1h-2,3,4,5-tetra-hydro-3-benzazepin-n-oxid og laegemidler, hvori det anvendes DK44386A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/696,377 US4686218A (en) 1985-01-30 1985-01-30 Use of 6-chloro-3-methyl-1H-2,3,4,5-tetrahydro-3-benzazepine-n-oxide, as a prodrug

Publications (2)

Publication Number Publication Date
DK44386D0 DK44386D0 (da) 1986-01-29
DK44386A true DK44386A (da) 1986-07-31

Family

ID=24796809

Family Applications (1)

Application Number Title Priority Date Filing Date
DK44386A DK44386A (da) 1985-01-30 1986-01-29 6-chlor-3-methyl-1h-2,3,4,5-tetra-hydro-3-benzazepin-n-oxid og laegemidler, hvori det anvendes

Country Status (10)

Country Link
US (1) US4686218A (da)
EP (1) EP0190860A3 (da)
JP (1) JPS61176525A (da)
AU (1) AU581956B2 (da)
CA (1) CA1244018A (da)
DK (1) DK44386A (da)
ES (1) ES8704903A1 (da)
GR (1) GR860230B (da)
PT (1) PT81917B (da)
ZA (1) ZA86659B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5036093A (en) * 1987-10-09 1991-07-30 Du Pont Merck Pharmaceutical Aminomethyl oxooxazolidinyl azacycloalkylbenzene derivatives useful as antibacterial agents
GB8923075D0 (en) * 1989-10-13 1989-11-29 Patterson Laurence H Anti-cancer compounds
GB9107843D0 (en) * 1991-04-12 1991-05-29 Patterson Laurence H Anti-cancer compounds
GB9107852D0 (en) * 1991-04-12 1991-05-29 Patterson Laurence H Anti-cancer compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3496166A (en) * 1967-12-22 1970-02-17 Ciba Geigy Corp 3-substituted 1-aryl-3-benzazepines
US3752892A (en) * 1970-03-11 1973-08-14 Ciba Geigy Corp Anorexigenic tetrahydrobenzazepine derivative method and composition thereof
US4465677A (en) * 1982-07-14 1984-08-14 Smithkline Beckman Corporation Pharmaceutical compositions and method of producing alpha2 antagonism
EP0108170A1 (en) * 1982-10-08 1984-05-16 Smithkline Beckman Corporation 3-Benzazepines as alpha-2 antagonists
EP0135545A1 (en) * 1983-02-19 1985-04-03 Beecham Group Plc Azabicycloalkyl benzamide and anilide derivatives

Also Published As

Publication number Publication date
ES8704903A1 (es) 1987-04-16
ZA86659B (en) 1986-12-30
DK44386D0 (da) 1986-01-29
EP0190860A3 (en) 1987-06-03
PT81917A (en) 1986-02-01
US4686218A (en) 1987-08-11
AU581956B2 (en) 1989-03-09
AU5265786A (en) 1986-08-07
GR860230B (en) 1986-05-28
JPS61176525A (ja) 1986-08-08
EP0190860A2 (en) 1986-08-13
CA1244018A (en) 1988-11-01
PT81917B (en) 1987-11-12
ES551361A0 (es) 1987-04-16

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Legal Events

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AHB Application shelved due to non-payment