DK429480A - PHOSPHONO HYDROXYDIC ACETIC ACID PROCEDURES FOR PREPARING IT AND USING IT AS A MEDICINE - Google Patents

PHOSPHONO HYDROXYDIC ACETIC ACID PROCEDURES FOR PREPARING IT AND USING IT AS A MEDICINE

Info

Publication number
DK429480A
DK429480A DK429480A DK429480A DK429480A DK 429480 A DK429480 A DK 429480A DK 429480 A DK429480 A DK 429480A DK 429480 A DK429480 A DK 429480A DK 429480 A DK429480 A DK 429480A
Authority
DK
Denmark
Prior art keywords
phosphono
hydroxydic
medicine
preparing
acetic acid
Prior art date
Application number
DK429480A
Other languages
Danish (da)
Inventor
F Lieb
H Oediger
G Streissle
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6083349&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK429480(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK429480A publication Critical patent/DK429480A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3808Acyclic saturated acids which can have further substituents on alkyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention relates to phosphono-hydroxyacetic acid and salts thereof of Formula I as defined hereinabove, useful as antiviral agents, e.g. antiherpes agents. Also included in the invention are pharmaceutical compositions and medicaments containing said compounds of Formula I as the active ingredients as well as methods for the use of said compounds, compositions and medicaments.
DK429480A 1979-10-12 1980-10-10 PHOSPHONO HYDROXYDIC ACETIC ACID PROCEDURES FOR PREPARING IT AND USING IT AS A MEDICINE DK429480A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792941384 DE2941384A1 (en) 1979-10-12 1979-10-12 PHOSPHONO-HYDROXY-ACETIC ACID, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS

Publications (1)

Publication Number Publication Date
DK429480A true DK429480A (en) 1981-04-13

Family

ID=6083349

Family Applications (1)

Application Number Title Priority Date Filing Date
DK429480A DK429480A (en) 1979-10-12 1980-10-10 PHOSPHONO HYDROXYDIC ACETIC ACID PROCEDURES FOR PREPARING IT AND USING IT AS A MEDICINE

Country Status (10)

Country Link
US (1) US4340599A (en)
EP (1) EP0027199B2 (en)
JP (1) JPS56115793A (en)
AT (1) ATE3552T1 (en)
AU (1) AU530678B2 (en)
CA (1) CA1163200A (en)
DE (2) DE2941384A1 (en)
DK (1) DK429480A (en)
ES (1) ES8106003A1 (en)
FI (1) FI803202L (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3039997A1 (en) * 1980-10-23 1982-06-03 Bayer Ag, 5090 Leverkusen PHOSPHONOHYDROXYACETONITRILE, A METHOD FOR THE PRODUCTION THEREOF AND ITS USE AS AN INTERMEDIATE PRODUCT FOR THE PRODUCTION OF MEDICINAL PRODUCTS
DE3039998A1 (en) * 1980-10-23 1982-06-03 Bayer Ag, 5090 Leverkusen PHOSPHONOFORMALDEHYDE, A METHOD FOR THE PRODUCTION THEREOF AND ITS USE AS AN INTERMEDIATE PRODUCT FOR THE PRODUCTION OF MEDICINAL PRODUCTS
US5059591B1 (en) * 1983-05-26 2000-04-25 Liposome Co Inc Drug preparations of reduced toxicity
PT78628B (en) * 1984-05-02 1986-06-18 Liposome Co Inc Pharmaceutical composition with reduced toxicity
FR2596393B1 (en) * 1986-04-01 1988-06-03 Sanofi Sa HYDROXY-3 DIHYDROXYOXOPHOSPHORIO-4 BUTANOIC ACID DERIVATIVES, THEIR PREPARATION PROCESS, THEIR USE AS MEDICAMENTS AND THE COMPOSITIONS CONTAINING THEM
US5760021A (en) * 1992-05-29 1998-06-02 The Procter & Gamble Company Phosphonocarboxylate compounds pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism
CN1042427C (en) * 1994-04-15 1999-03-10 大连理工大学 Synthetic method for 2-hydroxy-2-phosphono-acetic acid
AU5034899A (en) * 1998-07-15 2000-02-07 Jomaa Hassan Drugs containing phosphoric acid derivatives as active ingredient and their use
FR2995900B1 (en) 2012-09-27 2014-10-17 Chryso COPOLYMERS WITH GEM-ACETOPHOSPHONE GROUPS
CN103435644B (en) * 2013-09-09 2015-07-08 山东省泰和水处理有限公司 Preparation method of low chloride 2-hydroxyphosphonoacetic acid

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3032500A (en) * 1959-12-31 1962-05-01 American Cyanamid Co Sequestration of metal ions
US3159537A (en) * 1960-12-20 1964-12-01 American Cyanamid Co Potentiation of tetracycline by phosphinic acid
US3767795A (en) * 1971-02-25 1973-10-23 Abbott Lab Method for combating certain virus infection
DE2217692C3 (en) * 1972-04-13 1984-10-18 Henkel KGaA, 4000 Düsseldorf Complexing agent with polyvalent metal ions
US3965254A (en) * 1973-05-23 1976-06-22 The Procter & Gamble Company Compositions for the treatment of calcific tumors
DE2360797C2 (en) * 1973-12-06 1985-05-23 Henkel KGaA, 4000 Düsseldorf Pharmaceutical preparations
US4016264A (en) * 1975-07-14 1977-04-05 The University Of Utah Wart treatment with phosphonoacetic acid or derivatives thereof
US4092412A (en) * 1976-04-30 1978-05-30 Abbott Laboratories Treatment of herpes simplex infections
US4052439A (en) * 1976-04-30 1977-10-04 Abbott Laboratories Carboxylic esters of phosphonoacetic acid
SE7607496L (en) * 1976-07-01 1978-01-02 Astra Laekemedel Ab METHOD FOR FIGHTING VIRUS INFECTIONS
JPS542336A (en) * 1977-06-06 1979-01-09 Meiji Seika Kaisha Ltd Preventive and remedy for viral diseases
US4150125A (en) * 1977-09-30 1979-04-17 Abbott Laboratories Triglyceride ester of phosphonoacetic acid having antiviral activity

Also Published As

Publication number Publication date
EP0027199B2 (en) 1985-06-19
DE2941384A1 (en) 1981-04-23
JPS56115793A (en) 1981-09-11
CA1163200A (en) 1984-03-06
AU530678B2 (en) 1983-07-28
AU6250680A (en) 1981-04-16
US4340599A (en) 1982-07-20
ES495826A0 (en) 1981-07-01
ES8106003A1 (en) 1981-07-01
EP0027199A1 (en) 1981-04-22
ATE3552T1 (en) 1983-06-15
DE3063525D1 (en) 1983-07-07
EP0027199B1 (en) 1983-05-25
FI803202L (en) 1981-04-13

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Legal Events

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