DK4286A - Fremgangsmaade til fremstilling af en metalloproteinaseinhibitor - Google Patents

Fremgangsmaade til fremstilling af en metalloproteinaseinhibitor Download PDF

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Publication number
DK4286A
DK4286A DK4286A DK4286A DK4286A DK 4286 A DK4286 A DK 4286A DK 4286 A DK4286 A DK 4286A DK 4286 A DK4286 A DK 4286A DK 4286 A DK4286 A DK 4286A
Authority
DK
Denmark
Prior art keywords
metaloproteinase
inhibitor
preparing
metaloproteinase inhibitor
Prior art date
Application number
DK4286A
Other languages
English (en)
Other versions
DK4286D0 (da
Inventor
Timothy John Roy Harris
Andrew James Penrose Docherty
John James Reynolds
Gillian Murphy
Original Assignee
Celltech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858500341A external-priority patent/GB8500341D0/en
Application filed by Celltech Ltd filed Critical Celltech Ltd
Publication of DK4286D0 publication Critical patent/DK4286D0/da
Publication of DK4286A publication Critical patent/DK4286A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK4286A 1985-01-07 1986-01-06 Fremgangsmaade til fremstilling af en metalloproteinaseinhibitor DK4286A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858500341A GB8500341D0 (en) 1985-01-07 1985-01-07 Production of protein
GB858526951A GB8526951D0 (en) 1985-01-07 1985-11-01 Production of protein

Publications (2)

Publication Number Publication Date
DK4286D0 DK4286D0 (da) 1986-01-06
DK4286A true DK4286A (da) 1986-07-08

Family

ID=26288644

Family Applications (1)

Application Number Title Priority Date Filing Date
DK4286A DK4286A (da) 1985-01-07 1986-01-06 Fremgangsmaade til fremstilling af en metalloproteinaseinhibitor

Country Status (4)

Country Link
EP (1) EP0188312A3 (da)
AU (1) AU589935B2 (da)
DK (1) DK4286A (da)
GB (1) GB2169295A (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62500424A (ja) * 1984-10-01 1987-02-26 サンド・リミテッド 赤血球の増強活性を有する蛋白質のための遺伝子を含有するベクタ−および前記蛋白質を生産するための組み換えｄｎａ法
EP0211077B1 (en) * 1985-02-05 1993-05-05 Synergen Biologicals, Inc. Metalloproteinase inhibitor sequence recombinant vector system for using same and recombinant-dna method for the manufacture of same
WO1990014363A1 (en) * 1989-05-19 1990-11-29 Amgen Inc. Metalloproteinase inhibitor
US5714465A (en) 1989-05-19 1998-02-03 Amgen Inc. Method of inhibiting tumor cell dissemination with a metalloproteinase inhibitor
US5661034A (en) * 1991-07-18 1997-08-26 Fuji Yakuhin Kogyo Kabushiki Kaisha Serum-free medium for tissue culture containing tissue inhibitor of metalloproteinases and method for growing cells using the medium

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4276284A (en) * 1971-07-26 1981-06-30 Brown Stuart I Prevention of collagenase induced disease by treatment with collagenase inhibitors
CA1200773A (en) * 1980-02-29 1986-02-18 William J. Rutter Expression linkers
US4419446A (en) * 1980-12-31 1983-12-06 The United States Of America As Represented By The Department Of Health And Human Services Recombinant DNA process utilizing a papilloma virus DNA as a vector
US4438032A (en) * 1981-01-30 1984-03-20 The Regents Of The University Of California Unique T-lymphocyte line and products derived therefrom
AU577259B2 (en) * 1982-08-13 1988-09-22 Zymogenetics Inc. Glycolytic promters for regulated protein expression protease inhibitor
JPS62500424A (ja) * 1984-10-01 1987-02-26 サンド・リミテッド 赤血球の増強活性を有する蛋白質のための遺伝子を含有するベクタ−および前記蛋白質を生産するための組み換えｄｎａ法
ATE108205T1 (de) * 1984-12-06 1994-07-15 Synergen Biolog Inc Rekombinantverfahren zur herstellung von serinproteaseinhibitoren, sowie dns-sequenzen dazu.
DE3666826D1 (en) * 1985-01-18 1989-12-14 Searle & Co Human natural inhibitor of collagenases
EP0211077B1 (en) * 1985-02-05 1993-05-05 Synergen Biologicals, Inc. Metalloproteinase inhibitor sequence recombinant vector system for using same and recombinant-dna method for the manufacture of same

Also Published As

Publication number Publication date
GB2169295A (en) 1986-07-09
GB8600199D0 (en) 1986-02-12
EP0188312A2 (en) 1986-07-23
EP0188312A3 (en) 1988-01-13
AU5186586A (en) 1986-07-10
DK4286D0 (da) 1986-01-06
AU589935B2 (en) 1989-10-26

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment