DK42784A - PYRIDIN-PYRIMIDINON DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS - Google Patents

PYRIDIN-PYRIMIDINON DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS Download PDF

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Publication number
DK42784A
DK42784A DK42784A DK42784A DK42784A DK 42784 A DK42784 A DK 42784A DK 42784 A DK42784 A DK 42784A DK 42784 A DK42784 A DK 42784A DK 42784 A DK42784 A DK 42784A
Authority
DK
Denmark
Prior art keywords
ring
linear
compounds
pyrimidinon
pyridin
Prior art date
Application number
DK42784A
Other languages
Danish (da)
Other versions
DK42784D0 (en
Inventor
Helmut Schickaneder
Peter Moersdorf
Kurt Henning Ahrens
Stefan Postius
Istvan Szelenyi
Rolf Herter
Herbert Hansen
Original Assignee
Heumann Ludwig & Co Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heumann Ludwig & Co Gmbh filed Critical Heumann Ludwig & Co Gmbh
Publication of DK42784D0 publication Critical patent/DK42784D0/en
Publication of DK42784A publication Critical patent/DK42784A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Abstract

The invention relates to new pyridine-pyrimidinone derivatives corresponding to the following general formula <IMAGE> (I) wherein R1 represents linear C1-6 alkyl or cycloalkyl and R2 represents linear C1-6 alkyl or R1 and R2 together with the nitrogen atom form a pyrrolidine or piperidine ring; Alk represents a linear alkylene chain C1-6; Q represents a benzene ring, furan ring, thiophene ring or thiazole ring; X represents oxygen, Y is a single bond and m is 2, 3 or 4 when Q represents benzene; X represents methylene, Y represents sulfur and m is 2 or 3 when Q is furan, thiophene or thiazole; and R3 represents a hydrogen atom or a lower alkyl group. These compounds show improved H2-antagonistic activity.
DK42784A 1983-02-22 1984-01-31 PYRIDIN-PYRIMIDINON DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS DK42784A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3306102A DE3306102C1 (en) 1983-02-22 1983-02-22 Pyridine-pyrimidinone derivatives, processes for their preparation and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
DK42784D0 DK42784D0 (en) 1984-01-31
DK42784A true DK42784A (en) 1984-08-23

Family

ID=6191499

Family Applications (1)

Application Number Title Priority Date Filing Date
DK42784A DK42784A (en) 1983-02-22 1984-01-31 PYRIDIN-PYRIMIDINON DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS

Country Status (17)

Country Link
US (1) US4559344A (en)
EP (1) EP0119510B1 (en)
JP (1) JPS59163385A (en)
KR (1) KR840007595A (en)
AT (1) ATE26713T1 (en)
AU (1) AU562495B2 (en)
DE (2) DE3306102C1 (en)
DK (1) DK42784A (en)
ES (1) ES8407293A1 (en)
GR (1) GR79815B (en)
HU (1) HU192538B (en)
IE (1) IE840386L (en)
IL (1) IL70594A (en)
NZ (1) NZ206853A (en)
PT (1) PT78004B (en)
YU (1) YU254283A (en)
ZA (1) ZA839589B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8411954D0 (en) * 1984-05-10 1984-06-13 Glaxo Group Ltd Cephalosporin antibiotics
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1565966A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
US4521418A (en) * 1979-02-21 1985-06-04 Smith Kline & French Laboratories Limited Guanidinothiazolyl derivatives
CA1211111A (en) * 1982-02-15 1986-09-09 Isao Yanagisawa Process for preparing novel pyrimidone compounds
US4808589A (en) * 1982-02-20 1989-02-28 Smith Kline & French Laboratories Limited Pyrimidone derivatives

Also Published As

Publication number Publication date
DK42784D0 (en) 1984-01-31
JPS59163385A (en) 1984-09-14
PT78004B (en) 1986-04-10
NZ206853A (en) 1986-03-14
PT78004A (en) 1984-02-01
EP0119510A1 (en) 1984-09-26
HU192538B (en) 1987-06-29
US4559344A (en) 1985-12-17
ATE26713T1 (en) 1987-05-15
KR840007595A (en) 1984-12-08
AU562495B2 (en) 1987-06-11
GR79815B (en) 1984-10-31
YU254283A (en) 1986-06-30
AU2272383A (en) 1984-08-30
IL70594A0 (en) 1984-04-30
IE840386L (en) 1984-08-22
IL70594A (en) 1988-06-30
ES529415A0 (en) 1984-10-01
DE3463270D1 (en) 1987-05-27
EP0119510B1 (en) 1987-04-22
ZA839589B (en) 1984-09-26
ES8407293A1 (en) 1984-10-01
DE3306102C1 (en) 1984-08-02

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment