DK3954778T3 - Produktion af en blanding af neutrale ikke-fucosylerede oligosaccharider af en celle - Google Patents

Produktion af en blanding af neutrale ikke-fucosylerede oligosaccharider af en celle Download PDF

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Publication number
DK3954778T3
DK3954778T3 DK20190203.8T DK20190203T DK3954778T3 DK 3954778 T3 DK3954778 T3 DK 3954778T3 DK 20190203 T DK20190203 T DK 20190203T DK 3954778 T3 DK3954778 T3 DK 3954778T3
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DK
Denmark
Prior art keywords
fucosylate
oligosaccharides
cell
mixture
production
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Application number
DK20190203.8T
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English (en)
Inventor
Sofie Aesaert
Joeri Beauprez
Gert Peters
Original Assignee
Inbiose Nv
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Publication date
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Publication of DK3954778T3 publication Critical patent/DK3954778T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/04Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/18Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK20190203.8T 2020-08-10 2020-08-10 Produktion af en blanding af neutrale ikke-fucosylerede oligosaccharider af en celle DK3954778T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP20190203.8A EP3954778B1 (en) 2020-08-10 2020-08-10 Production of a mixture of neutral non-fucosylated oligosaccharides by a cell

Publications (1)

Publication Number Publication Date
DK3954778T3 true DK3954778T3 (da) 2023-12-18

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ID=72039376

Family Applications (1)

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DK20190203.8T DK3954778T3 (da) 2020-08-10 2020-08-10 Produktion af en blanding af neutrale ikke-fucosylerede oligosaccharider af en celle

Country Status (3)

Country Link
EP (1) EP3954778B1 (da)
DK (1) DK3954778T3 (da)
ES (1) ES2966260T3 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024042235A1 (en) * 2022-08-25 2024-02-29 Dsm Ip Assets B.V. Hybrid method for producing complex hmos

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113736721A (zh) 2010-07-12 2021-12-03 因比奥斯公司 用于生产附加值生物产品的代谢改造的生物
WO2012168495A1 (es) * 2011-06-07 2012-12-13 Hero Ag Obtención de oligosacaridos mediante un procedimiento biotecnológico

Also Published As

Publication number Publication date
EP3954778A1 (en) 2022-02-16
ES2966260T3 (es) 2024-04-19
EP3954778B1 (en) 2023-10-04

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