DK37790D0 - INDEX DERIVATIVES, THEIR PREPARATION AND USE - Google Patents

INDEX DERIVATIVES, THEIR PREPARATION AND USE

Info

Publication number
DK37790D0
DK37790D0 DK037790A DK37790A DK37790D0 DK 37790 D0 DK37790 D0 DK 37790D0 DK 037790 A DK037790 A DK 037790A DK 37790 A DK37790 A DK 37790A DK 37790 D0 DK37790 D0 DK 37790D0
Authority
DK
Denmark
Prior art keywords
straight
branched
preparation
hydrogen
carbon atoms
Prior art date
Application number
DK037790A
Other languages
Danish (da)
Other versions
DK37790A (en
Inventor
Lone Nielsen
Peter Hoengaard Andersen
Louis Brammer Hansen
Peter Faarup
John Bondo Hansen
Original Assignee
Ferrosan As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrosan As filed Critical Ferrosan As
Priority to DK037790A priority Critical patent/DK37790A/en
Publication of DK37790D0 publication Critical patent/DK37790D0/en
Priority to US07/645,381 priority patent/US5126363A/en
Priority to IE26091A priority patent/IE69761B1/en
Priority to IL9710591A priority patent/IL97105A/en
Priority to ZA91886A priority patent/ZA91886B/en
Priority to NZ237066A priority patent/NZ237066A/en
Priority to EP91904005A priority patent/EP0515462B1/en
Priority to AT91904005T priority patent/ATE123283T1/en
Priority to DE69110124T priority patent/DE69110124T2/en
Priority to JP3504066A priority patent/JPH05503525A/en
Priority to DK91904005.5T priority patent/DK0515462T3/en
Priority to PT96757A priority patent/PT96757B/en
Priority to AU73265/91A priority patent/AU641482B2/en
Priority to PCT/DK1991/000041 priority patent/WO1991012252A1/en
Priority to CA002074727A priority patent/CA2074727A1/en
Publication of DK37790A publication Critical patent/DK37790A/en
Priority to US07/864,734 priority patent/US5250538A/en
Priority to FI923492A priority patent/FI923492A0/en
Priority to NO92923153A priority patent/NO923153L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

Indole derivatives of formula (I) <IMAGE> (I) wherein R1, R2, R3 and R4 may be hydrogen or lower alkyl optionally substituted by halogen; A1 represents a straight or branched alkylene chain containing from 2 to 4 carbon atoms; R5 is hydrogen or a straight or branched alkyl group; A2 is a straight or branched, saturated or unsaturated hydrocarbon chain containing from 2 to 6 carbon atoms; and R6 is selected from a group consisting of various structures, have been found to exhibit central nervous system activities.
DK037790A 1990-02-13 1990-02-13 INDEX DERIVATIVES, THEIR PREPARATION AND USE DK37790A (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
DK037790A DK37790A (en) 1990-02-13 1990-02-13 INDEX DERIVATIVES, THEIR PREPARATION AND USE
US07/645,381 US5126363A (en) 1990-02-13 1991-01-23 Indole derivatives and their use
IE26091A IE69761B1 (en) 1990-02-13 1991-01-25 Indole derivatives their preparation and use
IL9710591A IL97105A (en) 1990-02-13 1991-01-31 Indole derivatives, their preparation and pharmaceutical compositions containing them
ZA91886A ZA91886B (en) 1990-02-13 1991-02-06 Indole derivatives,their preparation and use
NZ237066A NZ237066A (en) 1990-02-13 1991-02-11 Indole derivatives and pharmaceutical preparations
CA002074727A CA2074727A1 (en) 1990-02-13 1991-02-13 Indole derivatives, their preparation and use
DE69110124T DE69110124T2 (en) 1990-02-13 1991-02-13 INDOLDER DERIVATIVES, PRODUCTION AND USE.
AT91904005T ATE123283T1 (en) 1990-02-13 1991-02-13 INDOLE DERIVATIVES, PRODUCTION AND USE.
EP91904005A EP0515462B1 (en) 1990-02-13 1991-02-13 Indole derivatives, their preparation and use
JP3504066A JPH05503525A (en) 1990-02-13 1991-02-13 Indole derivatives, their production and use
DK91904005.5T DK0515462T3 (en) 1990-02-13 1991-02-13 Indole derivatives, processes for their preparation and their use
PT96757A PT96757B (en) 1990-02-13 1991-02-13 PROCESS FOR THE PREPARATION OF INDOOR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS
AU73265/91A AU641482B2 (en) 1990-02-13 1991-02-13 Indole derivatives, their preparation and use
PCT/DK1991/000041 WO1991012252A1 (en) 1990-02-13 1991-02-13 Indole derivatives, their preparation and use
US07/864,734 US5250538A (en) 1990-02-13 1992-04-07 Indole derivatives and their use
FI923492A FI923492A0 (en) 1990-02-13 1992-08-03 INDOLDERIVAT, DERAS FRAMSTAELLNING OCH ANVAENDNING.
NO92923153A NO923153L (en) 1990-02-13 1992-08-12 INDOL DERIVATIVES, THEIR PREPARATION AND USE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK037790A DK37790A (en) 1990-02-13 1990-02-13 INDEX DERIVATIVES, THEIR PREPARATION AND USE

Publications (2)

Publication Number Publication Date
DK37790D0 true DK37790D0 (en) 1990-02-13
DK37790A DK37790A (en) 1991-08-14

Family

ID=8092812

Family Applications (2)

Application Number Title Priority Date Filing Date
DK037790A DK37790A (en) 1990-02-13 1990-02-13 INDEX DERIVATIVES, THEIR PREPARATION AND USE
DK91904005.5T DK0515462T3 (en) 1990-02-13 1991-02-13 Indole derivatives, processes for their preparation and their use

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK91904005.5T DK0515462T3 (en) 1990-02-13 1991-02-13 Indole derivatives, processes for their preparation and their use

Country Status (16)

Country Link
US (1) US5126363A (en)
EP (1) EP0515462B1 (en)
JP (1) JPH05503525A (en)
AT (1) ATE123283T1 (en)
AU (1) AU641482B2 (en)
CA (1) CA2074727A1 (en)
DE (1) DE69110124T2 (en)
DK (2) DK37790A (en)
FI (1) FI923492A0 (en)
IE (1) IE69761B1 (en)
IL (1) IL97105A (en)
NO (1) NO923153L (en)
NZ (1) NZ237066A (en)
PT (1) PT96757B (en)
WO (1) WO1991012252A1 (en)
ZA (1) ZA91886B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2807577B2 (en) * 1990-06-15 1998-10-08 エーザイ株式会社 Cyclic amide derivative
EP1068199B1 (en) * 1998-04-08 2002-11-13 Wyeth N-aryloxyethyl-indoly-alkylamines for the treatment of depression
JP2002510682A (en) * 1998-04-08 2002-04-09 アメリカン・ホーム・プロダクツ・コーポレイション Indol-3-yl-cyclohexylamine derivative for treating depression (5-HT1 receptor antagonist)
US6162803A (en) * 1998-04-08 2000-12-19 American Home Products Corp. Indol-3-yl-cyclohexyl amine derivatives for the treatment of depression
US6150533A (en) * 1998-04-08 2000-11-21 American Home Products Corp. N-aryloxyethyl-indoly-alkylamines for the treatment of depression
WO2005023767A2 (en) 2003-09-10 2005-03-17 Brentwood Equities Ltd. Diastereomers of 4-aryloxy-3-hydroxypiperidines
US20100135851A1 (en) * 2008-12-01 2010-06-03 Estech, Llc Waste treatment autoclave to provide for steam - assisted drying

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3126395A (en) * 1964-03-24 Chj czhs
US3560495A (en) * 1965-05-08 1971-02-02 Ernst Frankus 1-heterocyclic amino methyl or 1-heterocyclic hydrazino methyl-3-phthalimido or (3',6'-dithia-3',4',5',6'-tetrahydrophthalimido)-pyrrolidinediones-2,5 or piperidinediones-2,6
US4061763A (en) * 1975-05-09 1977-12-06 Merck & Co., Inc. Tricyclicdicarboximides
US4139533A (en) * 1976-08-19 1979-02-13 Bristol-Myers Company Bicyclo[2,2,1]heptane-2,3-diendo carboxylic acid imide esters of quinoline carboxylic acid
US4748182A (en) * 1986-03-05 1988-05-31 Merrell Dow Pharmaceuticals Inc. Aromatic 2-aminoalkyl-1,2-benzoisothiazol-3(2H)one-1,1-dioxide derivatives and their use as anti-hypertensive and anxiolytic agents
DE3640641A1 (en) * 1986-11-28 1988-07-14 Thomae Gmbh Dr K NEW HETEROAROMATIC AMINE DERIVATIVES, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF

Also Published As

Publication number Publication date
CA2074727A1 (en) 1991-08-14
FI923492A (en) 1992-08-03
DK37790A (en) 1991-08-14
IE910260A1 (en) 1991-08-14
DK0515462T3 (en) 1995-10-02
EP0515462A1 (en) 1992-12-02
PT96757A (en) 1991-10-31
EP0515462B1 (en) 1995-05-31
NZ237066A (en) 1993-07-27
AU7326591A (en) 1991-09-03
FI923492A0 (en) 1992-08-03
NO923153D0 (en) 1992-08-12
IL97105A (en) 1994-11-28
PT96757B (en) 1998-07-31
ZA91886B (en) 1991-10-30
ATE123283T1 (en) 1995-06-15
NO923153L (en) 1992-08-12
JPH05503525A (en) 1993-06-10
DE69110124T2 (en) 1996-01-18
US5126363A (en) 1992-06-30
WO1991012252A1 (en) 1991-08-22
IE69761B1 (en) 1996-10-02
AU641482B2 (en) 1993-09-23
DE69110124D1 (en) 1995-07-06
IL97105A0 (en) 1992-03-29

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