DK3512616T4 - Method for monitoring, evaluating and controlling a cyclic chromatographic purification process - Google Patents

Method for monitoring, evaluating and controlling a cyclic chromatographic purification process Download PDF

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Publication number
DK3512616T4
DK3512616T4 DK18795675.0T DK18795675T DK3512616T4 DK 3512616 T4 DK3512616 T4 DK 3512616T4 DK 18795675 T DK18795675 T DK 18795675T DK 3512616 T4 DK3512616 T4 DK 3512616T4
Authority
DK
Denmark
Prior art keywords
evaluating
monitoring
controlling
purification process
chromatographic purification
Prior art date
Application number
DK18795675.0T
Other languages
Danish (da)
Other versions
DK3512616T3 (en
Inventor
Lars Aumann
Thomas Müller-Späth
Michael Bavand
Original Assignee
Chromacon Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=60629395&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3512616(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chromacon Ag filed Critical Chromacon Ag
Publication of DK3512616T3 publication Critical patent/DK3512616T3/en
Application granted granted Critical
Publication of DK3512616T4 publication Critical patent/DK3512616T4/en

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/86—Signal analysis
    • G01N30/8624—Detection of slopes or peaks; baseline correction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1807—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using counter-currents, e.g. fluidised beds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6034—Construction of the column joining multiple columns
DK18795675.0T 2017-11-16 2018-11-06 Method for monitoring, evaluating and controlling a cyclic chromatographic purification process DK3512616T4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17202010 2017-11-16
PCT/EP2018/080261 WO2019096622A1 (en) 2017-11-16 2018-11-06 Method for monitoring, evaluating, and controlling a cyclic chromatographic purification process

Publications (2)

Publication Number Publication Date
DK3512616T3 DK3512616T3 (en) 2020-02-03
DK3512616T4 true DK3512616T4 (en) 2022-09-19

Family

ID=60629395

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18795675.0T DK3512616T4 (en) 2017-11-16 2018-11-06 Method for monitoring, evaluating and controlling a cyclic chromatographic purification process

Country Status (15)

Country Link
US (1) US11460454B2 (en)
EP (1) EP3512616B2 (en)
JP (1) JP7333779B2 (en)
KR (1) KR102615965B1 (en)
CN (1) CN111356512B (en)
CA (1) CA3084473A1 (en)
DK (1) DK3512616T4 (en)
ES (1) ES2766200T5 (en)
HU (1) HUE047746T2 (en)
IL (1) IL274665B2 (en)
PL (1) PL3512616T5 (en)
PT (1) PT3512616T (en)
SG (1) SG11202003440SA (en)
SI (1) SI3512616T2 (en)
WO (1) WO2019096622A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3512616T2 (en) * 2017-11-16 2022-11-30 Chromacon Ag Method for monitoring, evaluating, and controlling a cyclic chromatographic purification process
EP4083053A1 (en) * 2021-04-30 2022-11-02 Fresenius Kabi iPSUM S.r.l. Method for icatibant preparation
IL310482A (en) * 2021-09-28 2024-03-01 Chromacon Ag Purification method and uses thereof
CN114712895B (en) * 2022-03-08 2023-04-28 江南大学 Double-part discarding method with additional chromatographic column for improving yield of simulated moving bed

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3053664B2 (en) * 1991-06-13 2000-06-19 積水化学工業株式会社 Apparatus for analyzing hemoglobins and method for analyzing hemoglobins using liquid chromatography
JPH09206502A (en) * 1995-12-01 1997-08-12 Daicel Chem Ind Ltd Pseudo moving bed type separator
DE19842550B4 (en) 1998-09-17 2004-08-05 Universität Dortmund Method for on-line parameter estimation and process observation for SMB chromatography processes
US6635173B2 (en) * 2000-12-28 2003-10-21 Cohesive Technologies, Inc. Multi column chromatography system
US6652746B2 (en) * 2002-03-26 2003-11-25 Biotage, Inc. Chromatography system for automatically separating different compounds in a sample
JP2004077329A (en) 2002-08-20 2004-03-11 Japan Organo Co Ltd Chromatography separator
EP1716900A1 (en) 2005-04-29 2006-11-02 Eidgenössische Technische Hochschule Zürich Method and device for chromatographic purification
EP1982752B1 (en) 2007-04-17 2010-08-25 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Method and device for chromatographic separation of components with partial recovery of mixed fractions
JP4985556B2 (en) * 2008-06-24 2012-07-25 株式会社島津製作所 Preparative liquid chromatograph apparatus and preparative purification method using the apparatus
GB0813579D0 (en) 2008-07-24 2008-09-03 Univ Brunel counter-current chromatographic arrangement
RU2508930C2 (en) * 2009-01-06 2014-03-10 Хромакон Аг Method of multicomponent gas cleaning and device to this end
EP2446257B1 (en) * 2009-06-26 2020-06-03 GE Healthcare Bio-Sciences AB A method in a chromatography system
CN101819192A (en) * 2010-05-14 2010-09-01 唐山建龙实业有限公司 Method for detecting naphthalene content in washing oil by gas chromatography
JP5802760B2 (en) * 2010-12-03 2015-11-04 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ Systems and processes for biopolymer chromatography
CN103969379B (en) * 2013-01-29 2017-07-18 深圳普门科技有限公司 The measured value adquisitiones that a kind of liquid chromatogram is examined
DK2772289T3 (en) * 2013-03-01 2015-08-10 Chromacon Ag Chromatographic method for the enrichment and isolation
US10099156B2 (en) 2013-04-08 2018-10-16 Chromacon Ag Chromatographic purification method
US10948483B2 (en) * 2013-04-08 2021-03-16 Chromacon Ag Method for control, monitoring and/or optimization of a chromatographic process
JP6558032B2 (en) * 2015-04-03 2019-08-14 株式会社島津製作所 Preparative chromatograph
AU2017313042A1 (en) * 2016-08-16 2019-04-04 Genzyme Corporation Methods of processing a fluid including a recombinant therapeutic protein and use thereof
JP7171058B2 (en) * 2017-02-21 2022-11-15 サイティバ・スウェーデン・アクチボラグ How to adapt the UV cell path length in a chromatography system
GB201702856D0 (en) 2017-02-22 2017-04-05 Ge Healthcare Bio Sciences Ab Method in continuous chromatography
SI3512616T2 (en) * 2017-11-16 2022-11-30 Chromacon Ag Method for monitoring, evaluating, and controlling a cyclic chromatographic purification process

Also Published As

Publication number Publication date
PL3512616T5 (en) 2022-12-19
SI3512616T2 (en) 2022-11-30
DK3512616T3 (en) 2020-02-03
JP7333779B2 (en) 2023-08-25
EP3512616B1 (en) 2019-11-20
JP2021503367A (en) 2021-02-12
SI3512616T1 (en) 2020-03-31
IL274665A (en) 2020-06-30
CN111356512B (en) 2022-08-09
IL274665B2 (en) 2024-02-01
RU2020116523A3 (en) 2021-12-16
US11460454B2 (en) 2022-10-04
PL3512616T3 (en) 2020-06-01
RU2020116523A (en) 2021-12-16
HUE047746T2 (en) 2020-05-28
ES2766200T3 (en) 2020-06-12
EP3512616B2 (en) 2022-07-27
EP3512616A1 (en) 2019-07-24
IL274665B1 (en) 2023-10-01
WO2019096622A1 (en) 2019-05-23
CA3084473A1 (en) 2019-05-23
PT3512616T (en) 2020-01-29
CN111356512A (en) 2020-06-30
KR20200088825A (en) 2020-07-23
ES2766200T5 (en) 2022-11-02
US20200355655A1 (en) 2020-11-12
SG11202003440SA (en) 2020-05-28
KR102615965B1 (en) 2023-12-19

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