DK3455269T3 - Implanterbare glucosesensorer med en biostabil overflade - Google Patents
Implanterbare glucosesensorer med en biostabil overflade Download PDFInfo
- Publication number
- DK3455269T3 DK3455269T3 DK17795688.5T DK17795688T DK3455269T3 DK 3455269 T3 DK3455269 T3 DK 3455269T3 DK 17795688 T DK17795688 T DK 17795688T DK 3455269 T3 DK3455269 T3 DK 3455269T3
- Authority
- DK
- Denmark
- Prior art keywords
- glucose sensors
- implantable glucose
- biostable
- biostable surface
- implantable
- Prior art date
Links
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title 1
- 239000008103 glucose Substances 0.000 title 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
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- A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
- A61B5/14865—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
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- A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
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- C09D175/08—Polyurethanes from polyethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2420/00—Materials or methods for coatings medical devices
- A61L2420/02—Methods for coating medical devices
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US201662334188P | 2016-05-10 | 2016-05-10 | |
PCT/IB2017/000636 WO2017195035A1 (en) | 2016-05-10 | 2017-05-10 | Implantable glucose sensors having a biostable surface |
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DK3455269T3 true DK3455269T3 (da) | 2023-12-18 |
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DK17795688.5T DK3455269T3 (da) | 2016-05-10 | 2017-05-10 | Implanterbare glucosesensorer med en biostabil overflade |
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US (1) | US20190142317A1 (da) |
EP (1) | EP3455269B1 (da) |
CA (1) | CA3063377A1 (da) |
DK (1) | DK3455269T3 (da) |
ES (1) | ES2965136T3 (da) |
FI (1) | FI3455269T3 (da) |
WO (1) | WO2017195035A1 (da) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2716502C (en) | 2009-05-15 | 2015-06-16 | Interface Biologics, Inc. | Antithrombogenic hollow fiber membranes and filters |
CA3041063C (en) | 2016-10-18 | 2021-06-08 | Interface Biologics, Inc. | Plasticized pvc admixtures with surface modifying macromolecules and articles made therefrom |
BR112020023530A2 (pt) | 2018-05-18 | 2021-02-09 | Evonik Canada Inc. | superfícies resistentes à adesão bacteriana |
US20190382578A1 (en) * | 2018-06-18 | 2019-12-19 | GM Global Technology Operations LLC | Fluorine-containing additives for non-fluoro thermoplastic polymers |
US10570292B1 (en) | 2018-10-09 | 2020-02-25 | GM Global Technology Operations LLC | Water-borne precursors for forming heterophasic anti-fouling, polymeric coatings having a fluorinated continuous phase with non-fluorinated domains |
US11421114B2 (en) | 2020-01-29 | 2022-08-23 | GM Global Technology Operations LLC | Precursors for forming heterophasic anti-fouling polymeric coatings |
CN116490128A (zh) * | 2020-10-05 | 2023-07-25 | 赞思健康科技有限公司 | 体内葡萄糖特异性传感器 |
Family Cites Families (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4484987A (en) | 1983-05-19 | 1984-11-27 | The Regents Of The University Of California | Method and membrane applicable to implantable sensor |
US4890620A (en) | 1985-09-20 | 1990-01-02 | The Regents Of The University Of California | Two-dimensional diffusion glucose substrate sensing electrode |
US6306594B1 (en) | 1988-11-14 | 2001-10-23 | I-Stat Corporation | Methods for microdispensing patterened layers |
US5165407A (en) | 1990-04-19 | 1992-11-24 | The University Of Kansas | Implantable glucose sensor |
US5322063A (en) | 1991-10-04 | 1994-06-21 | Eli Lilly And Company | Hydrophilic polyurethane membranes for electrochemical glucose sensors |
US5299571A (en) | 1993-01-22 | 1994-04-05 | Eli Lilly And Company | Apparatus and method for implantation of sensors |
US5390691A (en) | 1994-01-27 | 1995-02-21 | Sproule; Ronald | Bleed valve for water supply for camping vehicle |
US5391250A (en) | 1994-03-15 | 1995-02-21 | Minimed Inc. | Method of fabricating thin film sensors |
US5390671A (en) | 1994-03-15 | 1995-02-21 | Minimed Inc. | Transcutaneous sensor insertion set |
US5482473A (en) | 1994-05-09 | 1996-01-09 | Minimed Inc. | Flex circuit connector |
US5568806A (en) | 1995-02-16 | 1996-10-29 | Minimed Inc. | Transcutaneous sensor insertion set |
US5882494A (en) | 1995-03-27 | 1999-03-16 | Minimed, Inc. | Polyurethane/polyurea compositions containing silicone for biosensor membranes |
US5786439A (en) | 1996-10-24 | 1998-07-28 | Minimed Inc. | Hydrophilic, swellable coatings for biosensors |
US7885697B2 (en) | 2004-07-13 | 2011-02-08 | Dexcom, Inc. | Transcutaneous analyte sensor |
US6368274B1 (en) | 1999-07-01 | 2002-04-09 | Medtronic Minimed, Inc. | Reusable analyte sensor site and method of using the same |
US6413393B1 (en) | 1999-07-07 | 2002-07-02 | Minimed, Inc. | Sensor including UV-absorbing polymer and method of manufacture |
CA2395868C (en) | 2000-02-10 | 2009-07-14 | Medtronic Minimed, Inc. | Improved analyte sensor and method of making the same |
GB0116853D0 (en) * | 2001-07-10 | 2001-09-05 | Torsana Diabetes Diagnostics A | Optical sensor containing particles for in SITU measurement of analytes |
US6702857B2 (en) * | 2001-07-27 | 2004-03-09 | Dexcom, Inc. | Membrane for use with implantable devices |
US6915147B2 (en) | 2001-09-07 | 2005-07-05 | Medtronic Minimed, Inc. | Sensing apparatus and process |
US6671554B2 (en) | 2001-09-07 | 2003-12-30 | Medtronic Minimed, Inc. | Electronic lead for a medical implant device, method of making same, and method and apparatus for inserting same |
US6740072B2 (en) | 2001-09-07 | 2004-05-25 | Medtronic Minimed, Inc. | System and method for providing closed loop infusion formulation delivery |
US7323142B2 (en) | 2001-09-07 | 2008-01-29 | Medtronic Minimed, Inc. | Sensor substrate and method of fabricating same |
US6923936B2 (en) | 2001-10-23 | 2005-08-02 | Medtronic Minimed, Inc. | Sterile device and method for producing same |
EP1438029A4 (en) | 2001-10-23 | 2009-01-14 | Medtronic Minimed Inc | METHOD AND SYSTEM FOR NONVASCULAR SENSOR IMPLANTATION |
US7192766B2 (en) | 2001-10-23 | 2007-03-20 | Medtronic Minimed, Inc. | Sensor containing molded solidified protein |
US6809507B2 (en) | 2001-10-23 | 2004-10-26 | Medtronic Minimed, Inc. | Implantable sensor electrodes and electronic circuitry |
US20030077702A1 (en) | 2001-10-23 | 2003-04-24 | Rajiv Shah | Method for formulating a glucose oxidase enzyme with a desired property or properties and a glucose oxidase enzyme with the desired property |
US7500949B2 (en) | 2002-03-01 | 2009-03-10 | Medtronic Minimed, Inc. | Multilumen catheter |
US7226978B2 (en) | 2002-05-22 | 2007-06-05 | Dexcom, Inc. | Techniques to improve polyurethane membranes for implantable glucose sensors |
US7875293B2 (en) * | 2003-05-21 | 2011-01-25 | Dexcom, Inc. | Biointerface membranes incorporating bioactive agents |
JP4708342B2 (ja) | 2003-07-25 | 2011-06-22 | デックスコム・インコーポレーテッド | 埋設可能な装置に用いる酸素増大膜システム |
WO2005057175A2 (en) | 2003-12-09 | 2005-06-23 | Dexcom, Inc. | Signal processing for continuous analyte sensor |
US7364592B2 (en) * | 2004-02-12 | 2008-04-29 | Dexcom, Inc. | Biointerface membrane with macro-and micro-architecture |
US20050245799A1 (en) | 2004-05-03 | 2005-11-03 | Dexcom, Inc. | Implantable analyte sensor |
JP2008510154A (ja) | 2004-08-16 | 2008-04-03 | ノボ ノルディスク アクティーゼルスカブ | バイオセンサーのための多相系生物適合型の半透過性膜 |
US8744546B2 (en) | 2005-05-05 | 2014-06-03 | Dexcom, Inc. | Cellulosic-based resistance domain for an analyte sensor |
US7725148B2 (en) | 2005-09-23 | 2010-05-25 | Medtronic Minimed, Inc. | Sensor with layered electrodes |
EP2102258B1 (en) * | 2006-12-14 | 2016-10-19 | Interface Biologics Inc. | Surface modifying macromolecules with high degradation temperatures and uses thereof |
US20080275318A1 (en) * | 2007-04-20 | 2008-11-06 | Becton, Dickinson And Company | Biosensors for measuring analytes in the interstitial fluid |
PL2296581T3 (pl) * | 2008-06-20 | 2018-05-30 | Coloplast A/S | Biomateriał |
EP2321360B1 (en) * | 2008-08-28 | 2020-11-25 | Evonik Canada Inc. | Thermally stable biuret and isocyanurate based surface modifying macromolecules and uses thereof |
KR101331056B1 (ko) * | 2009-05-15 | 2013-11-19 | 인터페이스 바이오로직스 인크. | 항혈전성 중공 섬유막 및 필터 |
CA2716502C (en) * | 2009-05-15 | 2015-06-16 | Interface Biologics, Inc. | Antithrombogenic hollow fiber membranes and filters |
JP2013514278A (ja) * | 2009-12-18 | 2013-04-25 | インターフェース バイオロジクス,インコーポレーテッド | 自己集合コーティングからの薬物の局所送達 |
WO2014043204A1 (en) | 2012-09-14 | 2014-03-20 | Senseonics, Incorporated | Integrated catalytic protection of oxidation sensitive materials |
US8844057B2 (en) | 2012-10-01 | 2014-09-23 | Dexcom, Inc. | Analyte data retriever |
US10463471B2 (en) | 2013-07-18 | 2019-11-05 | Medos International Sarl | Methods and devices for positioning and securing ligament grafts |
US9814389B2 (en) | 2013-12-31 | 2017-11-14 | Senseonics, Incorporated | Continuous analyte monitoring system |
US10028659B2 (en) * | 2015-03-26 | 2018-07-24 | Verily Life Sciences Llc | Aptamer-based sensors, implantable devices and detection system |
-
2017
- 2017-05-10 WO PCT/IB2017/000636 patent/WO2017195035A1/en unknown
- 2017-05-10 US US16/300,404 patent/US20190142317A1/en active Pending
- 2017-05-10 EP EP17795688.5A patent/EP3455269B1/en active Active
- 2017-05-10 CA CA3063377A patent/CA3063377A1/en active Pending
- 2017-05-10 FI FIEP17795688.5T patent/FI3455269T3/fi active
- 2017-05-10 DK DK17795688.5T patent/DK3455269T3/da active
- 2017-05-10 ES ES17795688T patent/ES2965136T3/es active Active
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WO2017195035A1 (en) | 2017-11-16 |
ES2965136T3 (es) | 2024-04-11 |
EP3455269A1 (en) | 2019-03-20 |
EP3455269B1 (en) | 2023-09-20 |
US20190142317A1 (en) | 2019-05-16 |
CA3063377A1 (en) | 2017-11-16 |
FI3455269T3 (fi) | 2023-11-30 |
EP3455269A4 (en) | 2020-01-15 |
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