DK3426641T3 - Immunoproteasominhibitoranaloger - Google Patents
Immunoproteasominhibitoranaloger Download PDFInfo
- Publication number
- DK3426641T3 DK3426641T3 DK17764239.4T DK17764239T DK3426641T3 DK 3426641 T3 DK3426641 T3 DK 3426641T3 DK 17764239 T DK17764239 T DK 17764239T DK 3426641 T3 DK3426641 T3 DK 3426641T3
- Authority
- DK
- Denmark
- Prior art keywords
- immunoproteasominhibitor
- analogs
- immunoproteasominhibitor analogs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06052—Val-amino acid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662307370P | 2016-03-11 | 2016-03-11 | |
US201662307433P | 2016-03-12 | 2016-03-12 | |
PCT/US2017/021931 WO2017156471A1 (en) | 2016-03-11 | 2017-03-10 | Immunoproteasome inhibitor analogs |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3426641T3 true DK3426641T3 (da) | 2022-01-17 |
Family
ID=59789857
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK20196268.5T DK3778578T3 (da) | 2016-03-11 | 2017-03-10 | Immunoproteasominhibitoranaloger til behandling af inflammatoriske sygdomme |
DK17764239.4T DK3426641T3 (da) | 2016-03-11 | 2017-03-10 | Immunoproteasominhibitoranaloger |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK20196268.5T DK3778578T3 (da) | 2016-03-11 | 2017-03-10 | Immunoproteasominhibitoranaloger til behandling af inflammatoriske sygdomme |
Country Status (4)
Country | Link |
---|---|
US (1) | US10584105B2 (da) |
EP (2) | EP3778578B1 (da) |
DK (2) | DK3778578T3 (da) |
WO (1) | WO2017156471A1 (da) |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2210881A1 (en) * | 2009-01-14 | 2010-07-28 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Derivatives of syringolin A |
US9221772B2 (en) | 2009-12-03 | 2015-12-29 | The Regents Of The University Of California | Synthesis of syrbactin proteasome inhibitors |
EP2861565B1 (en) * | 2012-06-15 | 2016-12-21 | The Regents of the University of California | Syringolin and glidobactin analogs as proteasome inhibitors for the treatment of cancer |
WO2014008204A2 (en) * | 2012-07-02 | 2014-01-09 | Pono Corporation | Structures of proteasome inhibitors and methods for synthesizing and use thereof |
WO2014183015A1 (en) | 2013-05-09 | 2014-11-13 | Brown University | Macrocyclic proteasome inhibitors |
DK3172213T3 (da) | 2014-07-21 | 2021-12-13 | Dana Farber Cancer Inst Inc | Makrocykliske kinasehæmmere og anvendelser deraf |
-
2017
- 2017-03-10 EP EP20196268.5A patent/EP3778578B1/en active Active
- 2017-03-10 DK DK20196268.5T patent/DK3778578T3/da active
- 2017-03-10 EP EP17764239.4A patent/EP3426641B1/en active Active
- 2017-03-10 WO PCT/US2017/021931 patent/WO2017156471A1/en active Application Filing
- 2017-03-10 DK DK17764239.4T patent/DK3426641T3/da active
- 2017-03-10 US US16/078,348 patent/US10584105B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US10584105B2 (en) | 2020-03-10 |
DK3778578T3 (da) | 2022-06-20 |
EP3778578A1 (en) | 2021-02-17 |
US20190047969A1 (en) | 2019-02-14 |
WO2017156471A1 (en) | 2017-09-14 |
EP3426641A4 (en) | 2019-10-02 |
EP3778578B1 (en) | 2022-05-04 |
EP3426641A1 (en) | 2019-01-16 |
EP3426641B1 (en) | 2021-11-24 |
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