DK3405201T3 - Stabiliseret amorft calciumcarbonat til behandling af neurologiske, muskel- og infertilitetssygdomme eller tilstande - Google Patents

Stabiliseret amorft calciumcarbonat til behandling af neurologiske, muskel- og infertilitetssygdomme eller tilstande Download PDF

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Publication number
DK3405201T3
DK3405201T3 DK17741180.8T DK17741180T DK3405201T3 DK 3405201 T3 DK3405201 T3 DK 3405201T3 DK 17741180 T DK17741180 T DK 17741180T DK 3405201 T3 DK3405201 T3 DK 3405201T3
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Denmark
Prior art keywords
muscular
neurological
treatment
conditions
calcium carbonate
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Application number
DK17741180.8T
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English (en)
Inventor
Yosef Ben
Amir Arav
Abraham Shahar
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Amorphical Ltd
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Publication of DK3405201T3 publication Critical patent/DK3405201T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10Carbonates; Bicarbonates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0604Whole embryos; Culture medium therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0608Germ cells
    • C12N5/061Sperm cells, spermatogonia
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0608Germ cells
    • C12N5/0612Germ cells sorting of gametes, e.g. according to sex or motility
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • C12N2500/10Metals; Metal chelators
    • C12N2500/12Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
    • C12N2500/14Calcium; Ca chelators; Calcitonin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
DK17741180.8T 2016-01-18 2017-01-17 Stabiliseret amorft calciumcarbonat til behandling af neurologiske, muskel- og infertilitetssygdomme eller tilstande DK3405201T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662279843P 2016-01-18 2016-01-18
US201662279844P 2016-01-18 2016-01-18
US201662279845P 2016-01-18 2016-01-18
US201662376428P 2016-08-18 2016-08-18
PCT/IL2017/050059 WO2017125918A1 (en) 2016-01-18 2017-01-17 Stabilized amorphous calcium carbonate for treatment of neurological, muscular and infertility diseases or conditions

Publications (1)

Publication Number Publication Date
DK3405201T3 true DK3405201T3 (da) 2023-08-21

Family

ID=59361712

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17741180.8T DK3405201T3 (da) 2016-01-18 2017-01-17 Stabiliseret amorft calciumcarbonat til behandling af neurologiske, muskel- og infertilitetssygdomme eller tilstande

Country Status (13)

Country Link
US (2) US10758566B2 (da)
EP (2) EP4257141A3 (da)
JP (2) JP6873389B2 (da)
KR (1) KR20180109941A (da)
CN (1) CN108778296A (da)
AU (2) AU2017208953B2 (da)
BR (1) BR112018014520A2 (da)
CA (2) CA3011667A1 (da)
DK (1) DK3405201T3 (da)
ES (1) ES2952537T3 (da)
IL (1) IL260548B2 (da)
RU (1) RU2757419C2 (da)
WO (1) WO2017125918A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110121351A (zh) 2016-10-25 2019-08-13 艾玛菲克有限公司 用于治疗白血病的无定形碳酸钙
CA3144221A1 (en) * 2019-07-23 2021-01-28 Amorphical Ltd Amorphous calcium carbonate for improving athletic performance
EP4117685A4 (en) * 2020-03-11 2024-03-20 Amorphical Ltd AMORPHOUS CALCIUM CARBONATE FOR THE TREATMENT OF ACIDOSIS
IT202200010592A1 (it) * 2022-05-23 2023-11-23 Neilos S R L “Composizione nutraceutica o farmaceutica per l’infertilità maschile”
IT202200010583A1 (it) * 2022-05-23 2023-11-23 Neilos S R L “Composizione nutraceutica o farmaceutica per l’infertilità maschile”

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4757017A (en) 1984-09-14 1988-07-12 Mcw Research Foundation, Inc. In vitro cell culture system
EP1048724A1 (en) * 1999-04-27 2000-11-02 Transgene S.A. Human myoblast cell lines and their uses
CA2536112A1 (en) 2003-08-20 2005-03-03 Northern Sydney And Central Coast Area Health Service Methods for enhancing embryo viability
EP1670902A4 (en) * 2003-09-08 2008-05-07 Univ Texas METHOD AND COMPOSITION FOR ENHANCING IN VITRO EMBRYONIC DEVELOPMENT BY ENRICHING A CULTURE MEDIUM COMPRISING PROSTAGLANDIN OR PROSTAGLANDIN ANALOGUE
PL1758599T3 (pl) 2004-05-26 2014-04-30 Ben Gurion Univ Of The Negev Research And Development Authority Kompozycja do podania doustnego zawierająca stabilny amorficzny węglan wapnia
US20080039531A1 (en) * 2005-06-13 2008-02-14 Alfred Stracher Compositions, and kits comprising targeted aldehyde or acetal protease inhibitor compounds for treating muscle disorders
RU2462458C2 (ru) * 2006-02-10 2012-09-27 Байомарин Ига Лимитед Лечение миодистрофии дюшена
IL178495A (en) * 2006-10-05 2014-12-31 Univ Ben Gurion Use of cancerous gastric components or artificial calcium containing carbonate, chitin and polypeptide preparations to treat calcium metabolism-related or calcium-signaling conditions
EP2211873B1 (en) * 2007-10-22 2012-08-08 Amorphical Ltd. Stable amorphous calcium carbonate comprising phosphorylated amino acids
ES2831699T3 (es) * 2011-12-13 2021-06-09 Amorphical Ltd Un carbonato de calcio morfo para el tratamiento de la mala absorción de calcio y los trastornos metabólicos óseos
JP6263181B2 (ja) 2012-08-07 2018-01-17 アモーフィカル リミテッド. 安定化させた非晶質炭酸カルシウムの製造方法
EA201591152A1 (ru) * 2013-02-11 2016-03-31 Аморфикал Лтд. Аморфный карбонат кальция для ускоренного роста костной ткани
EP3174828A4 (en) 2014-07-31 2018-01-17 Amorphical Ltd. Non-aqueous liquid and semi-solid formulations of amorphous calcium carbonate
JP7007716B2 (ja) 2015-06-04 2022-01-25 アモーフィカル リミテッド. ポリリン酸塩又はビスホスホネートで安定化した非晶質炭酸カルシウム
KR20180109940A (ko) 2016-01-18 2018-10-08 아모피컬 리미티드 세포 배양 배지용 보충물로서의 안정화된 무정형 탄산칼슘

Also Published As

Publication number Publication date
JP7190760B2 (ja) 2022-12-16
JP2019501947A (ja) 2019-01-24
WO2017125918A1 (en) 2017-07-27
IL260548B2 (en) 2024-04-01
US20200345764A1 (en) 2020-11-05
AU2017208953B2 (en) 2022-11-03
JP2023029914A (ja) 2023-03-07
KR20180109941A (ko) 2018-10-08
US11207347B2 (en) 2021-12-28
RU2018129457A (ru) 2020-02-20
ES2952537T3 (es) 2023-11-02
EP3405201B1 (en) 2023-05-17
EP4257141A2 (en) 2023-10-11
AU2022252805A1 (en) 2022-11-10
EP3405201A4 (en) 2019-06-26
CA3011667A1 (en) 2017-07-27
CA3239809A1 (en) 2017-07-27
RU2757419C2 (ru) 2021-10-15
JP6873389B2 (ja) 2021-05-19
BR112018014520A2 (pt) 2018-12-11
CN108778296A (zh) 2018-11-09
EP3405201A1 (en) 2018-11-28
EP4257141A3 (en) 2023-11-22
RU2018129457A3 (da) 2020-10-21
AU2017208953A1 (en) 2018-09-06
US20190030068A1 (en) 2019-01-31
US10758566B2 (en) 2020-09-01
JP2021105026A (ja) 2021-07-26
IL260548B1 (en) 2023-12-01
IL260548A (da) 2018-09-20

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