DK3389653T3 - 2-iminobiotin til anvendelse i behandling af hjernecellelæsion - Google Patents
2-iminobiotin til anvendelse i behandling af hjernecellelæsion Download PDFInfo
- Publication number
- DK3389653T3 DK3389653T3 DK16825913.3T DK16825913T DK3389653T3 DK 3389653 T3 DK3389653 T3 DK 3389653T3 DK 16825913 T DK16825913 T DK 16825913T DK 3389653 T3 DK3389653 T3 DK 3389653T3
- Authority
- DK
- Denmark
- Prior art keywords
- iminobiotin
- treatment
- brain cell
- cell lesion
- lesion
- Prior art date
Links
- WWVANQJRLPIHNS-BKPPORCPSA-N 2-iminobiotin Chemical compound N1C(=N)N[C@H]2[C@H](CCCCC(=O)O)SC[C@H]21 WWVANQJRLPIHNS-BKPPORCPSA-N 0.000 title 1
- 210000004958 brain cell Anatomy 0.000 title 1
- 230000003902 lesion Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Dermatology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15200492 | 2015-12-16 | ||
PCT/NL2016/050880 WO2017105237A1 (en) | 2015-12-16 | 2016-12-16 | 2-iminobiotin for use in the treatment of brain cell injury |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3389653T3 true DK3389653T3 (da) | 2024-01-02 |
Family
ID=54936830
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK16825913.3T DK3389653T3 (da) | 2015-12-16 | 2016-12-16 | 2-iminobiotin til anvendelse i behandling af hjernecellelæsion |
Country Status (11)
Country | Link |
---|---|
US (3) | US10525039B2 (da) |
EP (1) | EP3389653B1 (da) |
JP (1) | JP6975165B2 (da) |
AU (1) | AU2016372396B2 (da) |
CA (1) | CA3008790A1 (da) |
DK (1) | DK3389653T3 (da) |
ES (1) | ES2965754T3 (da) |
FI (1) | FI3389653T3 (da) |
PL (1) | PL3389653T3 (da) |
PT (1) | PT3389653T (da) |
WO (1) | WO2017105237A1 (da) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK3389653T3 (da) * | 2015-12-16 | 2024-01-02 | Neurophyxia B V | 2-iminobiotin til anvendelse i behandling af hjernecellelæsion |
WO2019157277A1 (en) * | 2018-02-09 | 2019-08-15 | Yale University | Methods, systems and compositions for normothermic ex vivo restoration and preservation of intact organs |
WO2022203505A1 (en) * | 2021-03-23 | 2022-09-29 | Neurophyxia B.V. | 2-iminobiotin for use in the treatment of stroke |
WO2022203504A1 (en) * | 2021-03-23 | 2022-09-29 | Neurophyxia B.V. | 2-iminobiotin for use in the treatment of stroke |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SK9602001A3 (en) | 1999-01-21 | 2002-06-04 | Bristol Myers Squibb Co | Complex of ras-farnesyltransferase inhibitor and sulfobutylether-7-beta-cyclodextrin or 2-hydroxypropyl-beta-cyclodextrin and method |
US7087633B2 (en) * | 2000-03-31 | 2006-08-08 | Universitair Medisch Centrum | Method for treating perinatal asphyxia in a human or animal neonate |
EP1280526B1 (en) | 2000-03-31 | 2005-06-01 | Universitair Medisch Centrum Utrecht | Use of 2-iminobiotin for the manufacture of a medicament for the prevention and/or treatment, in newborn babies, of the effects of complications during childbirth |
US7319090B2 (en) | 2002-11-27 | 2008-01-15 | University Of North Carolina At Chapel Hill | Methods of treating cerebral ischemia |
CA2664399A1 (en) | 2006-10-04 | 2008-01-10 | Neurokey A/S | Use of hypothermia inducing drugs |
NZ604498A (en) | 2010-05-26 | 2014-10-31 | Neurophyxia B V | 2-iminobiotin formulations and uses thereof |
AU2013264820A1 (en) * | 2012-05-23 | 2014-11-27 | Cellixbio Private Limited | Compositions and methods for treatment of mucositis |
GB2504263B (en) * | 2012-06-08 | 2015-09-16 | Gw Pharma Ltd | Synergistic therapies for neuroprotection |
US10092591B2 (en) * | 2014-02-27 | 2018-10-09 | University Of Alaska Fairbanks | Methods and compositions for the treatment of ischemic injury to tissue using therapeutic hypothermia |
DK3389653T3 (da) | 2015-12-16 | 2024-01-02 | Neurophyxia B V | 2-iminobiotin til anvendelse i behandling af hjernecellelæsion |
-
2016
- 2016-12-16 DK DK16825913.3T patent/DK3389653T3/da active
- 2016-12-16 JP JP2018551742A patent/JP6975165B2/ja active Active
- 2016-12-16 EP EP16825913.3A patent/EP3389653B1/en active Active
- 2016-12-16 ES ES16825913T patent/ES2965754T3/es active Active
- 2016-12-16 FI FIEP16825913.3T patent/FI3389653T3/fi active
- 2016-12-16 WO PCT/NL2016/050880 patent/WO2017105237A1/en active Application Filing
- 2016-12-16 US US16/060,005 patent/US10525039B2/en active Active
- 2016-12-16 CA CA3008790A patent/CA3008790A1/en active Pending
- 2016-12-16 PT PT168259133T patent/PT3389653T/pt unknown
- 2016-12-16 AU AU2016372396A patent/AU2016372396B2/en active Active
- 2016-12-16 PL PL16825913.3T patent/PL3389653T3/pl unknown
-
2020
- 2020-01-03 US US16/734,226 patent/US10722496B2/en active Active
- 2020-07-10 US US16/926,123 patent/US11426387B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
JP2019501969A (ja) | 2019-01-24 |
ES2965754T3 (es) | 2024-04-16 |
AU2016372396B2 (en) | 2022-04-14 |
CA3008790A1 (en) | 2017-06-22 |
PT3389653T (pt) | 2023-12-28 |
US10722496B2 (en) | 2020-07-28 |
FI3389653T3 (fi) | 2023-12-18 |
US11426387B2 (en) | 2022-08-30 |
US10525039B2 (en) | 2020-01-07 |
EP3389653B1 (en) | 2023-11-08 |
AU2016372396A1 (en) | 2018-06-28 |
EP3389653A1 (en) | 2018-10-24 |
US20200338046A1 (en) | 2020-10-29 |
JP6975165B2 (ja) | 2021-12-01 |
US20200147049A1 (en) | 2020-05-14 |
US20190262316A1 (en) | 2019-08-29 |
WO2017105237A1 (en) | 2017-06-22 |
PL3389653T3 (pl) | 2024-02-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK3119397T3 (da) | Heterocykliske forbindelser til anvendelse i behandling af PI3K-gamma-medierede lidelser | |
DK3334422T3 (da) | Anvendelse af cannabidiolsyre i behandling af epilepsi | |
DK3395354T3 (da) | Plasminogen til anvendelse i behandling af diabetisk nefropati | |
DK3307262T3 (da) | Forbindelser til anvendelse ved behandling af neuromuskulære lidelser | |
DK3882250T3 (da) | Tetrahydropyranyl-amino-pyrrolopyrimidinon til anvendelse i behandling af btk-medierede forstyrrelser | |
DK3481846T3 (da) | 11-substituerede 24-hydroxysteroler til anvendelse til behandling af nmda-relaterede tilstande | |
DK3811943T3 (da) | Forbindelse til anvendelse til behandling af øjenlidelser | |
DK3185957T3 (da) | Patisiran til anvendelse ved behandlingen af transthyretin-medieret amyloidosis | |
DK3240612T3 (da) | Fremgangsmåder til behandling af nethindesygdomme | |
DK3362066T3 (da) | Kombinationsterapi til behandling af maligniteter | |
DK3390390T3 (da) | Bipyrazolylderivater egnede til behandling af autoimmunsygdomme | |
DK3197472T3 (da) | Rekombinante phe-frie proteiner til anvendelse i behandlingen af phenylketonuri | |
DK3307296T3 (da) | Timp2 til anvendelse til behandling af aldringsassocierede tilstande | |
DK3391902T3 (da) | Plasminogen til anvendelse i behandlingen af diabetisk angiokardiopati | |
DK3265087T3 (da) | Fremgangsmåde til behandling med tradipitant | |
DK3524255T3 (da) | Sammensætning til behandling af acne | |
DK3456330T3 (da) | Cortexolon-17alpha-valerat til anvendelse ved behandling af tumorer | |
DK3302519T3 (da) | Ornithodoros-moubata-komplement-inhibitor til anvendelse i behandlingen af akut graft-versus-host-sygdom | |
DK3374497T3 (da) | Modificerede makrofager til anvendelse i behandlingen af kræft | |
DK3556383T3 (da) | Plasminogen til anvendelse ved behandling af diabetes | |
DK3373874T3 (da) | Medicinsk forbinding | |
DK2994157T3 (da) | Tafa4-forbindelser og anvendelser deraf til behandling af smerte | |
DK3416580T3 (da) | Enhed til bestråling af huden | |
DK3191103T3 (da) | Sammensætninger og fremgangsmåder til behandling af præcancerøse hudlæsioner | |
DK3122308T3 (da) | Indretning til behandling af smerte |