DK3227277T3 - ANTIMYCOTIC RELATIONSHIP - Google Patents

ANTIMYCOTIC RELATIONSHIP Download PDF

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Publication number
DK3227277T3
DK3227277T3 DK15808770.0T DK15808770T DK3227277T3 DK 3227277 T3 DK3227277 T3 DK 3227277T3 DK 15808770 T DK15808770 T DK 15808770T DK 3227277 T3 DK3227277 T3 DK 3227277T3
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DK
Denmark
Prior art keywords
antimycotic
relationship
antimycotic relationship
Prior art date
Application number
DK15808770.0T
Other languages
Danish (da)
Inventor
Mihiro Sunose
Thomas Christopher Colley
Kazuhiro Ito
Garth Rapeport
Peter Strong
Original Assignee
Pulmocide Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pulmocide Ltd filed Critical Pulmocide Ltd
Application granted granted Critical
Publication of DK3227277T3 publication Critical patent/DK3227277T3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F1/00Details not covered by groups G06F3/00 - G06F13/00 and G06F21/00
    • G06F1/26Power supply means, e.g. regulation thereof
    • G06F1/32Means for saving power
    • G06F1/3203Power management, i.e. event-based initiation of a power-saving mode
    • G06F1/3234Power saving characterised by the action undertaken
    • G06F1/325Power saving in peripheral device
    • G06F1/3268Power saving in hard disk drive
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11CSTATIC STORES
    • G11C11/00Digital stores characterised by the use of particular electric or magnetic storage elements; Storage elements therefor
    • G11C11/21Digital stores characterised by the use of particular electric or magnetic storage elements; Storage elements therefor using electric elements
    • G11C11/34Digital stores characterised by the use of particular electric or magnetic storage elements; Storage elements therefor using electric elements using semiconductor devices
    • G11C11/40Digital stores characterised by the use of particular electric or magnetic storage elements; Storage elements therefor using electric elements using semiconductor devices using transistors
    • G11C11/401Digital stores characterised by the use of particular electric or magnetic storage elements; Storage elements therefor using electric elements using semiconductor devices using transistors forming cells needing refreshing or charge regeneration, i.e. dynamic cells
    • G11C11/4063Auxiliary circuits, e.g. for addressing, decoding, driving, writing, sensing or timing
    • G11C11/407Auxiliary circuits, e.g. for addressing, decoding, driving, writing, sensing or timing for memory cells of the field-effect type
    • G11C11/4074Power supply or voltage generation circuits, e.g. bias voltage generators, substrate voltage generators, back-up power, power control circuits
DK15808770.0T 2014-12-05 2015-12-04 ANTIMYCOTIC RELATIONSHIP DK3227277T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14196662 2014-12-05
PCT/GB2015/053731 WO2016087878A1 (en) 2014-12-05 2015-12-04 Antimycotic compound

Publications (1)

Publication Number Publication Date
DK3227277T3 true DK3227277T3 (en) 2020-04-27

Family

ID=52006914

Family Applications (2)

Application Number Title Priority Date Filing Date
DK15808770.0T DK3227277T3 (en) 2014-12-05 2015-12-04 ANTIMYCOTIC RELATIONSHIP
DK15817507.5T DK3227278T3 (en) 2014-12-05 2015-12-04 ANTIMYCOTIC RELATIONSHIP

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK15817507.5T DK3227278T3 (en) 2014-12-05 2015-12-04 ANTIMYCOTIC RELATIONSHIP

Country Status (19)

Country Link
US (12) US10106531B2 (en)
EP (2) EP3227277B1 (en)
JP (2) JP6669751B2 (en)
KR (1) KR102579848B1 (en)
CN (2) CN107001343B (en)
AU (1) AU2015356795B2 (en)
BR (1) BR112017008481B1 (en)
CA (1) CA2963625C (en)
DK (2) DK3227277T3 (en)
EA (1) EA033736B1 (en)
ES (2) ES2786374T3 (en)
HK (1) HK1244795A1 (en)
HU (2) HUE048685T2 (en)
IL (1) IL251631B (en)
MX (1) MX370412B (en)
PL (1) PL3227277T3 (en)
PT (1) PT3227277T (en)
SG (1) SG11201702835RA (en)
WO (2) WO2016087878A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102579848B1 (en) 2014-12-05 2023-09-18 풀모사이드 리미티드 Antimycotic compound
WO2016097761A1 (en) 2014-12-18 2016-06-23 Pulmocide Limited 4,5-dihydro-6h-thieno[3,2-d]benzazepine derivatives and their use to treat respiratory syncytial virus (rsv) infections
DK3298006T3 (en) 2015-05-21 2020-03-30 Pulmocide Ltd ANTIFUNGAL 4- (4- (4 - (((3R, 5R) -5 -) ((1H-1,2,4-TRIAZOL-1-YL) METHYL) -5- (2,4-DIFLUORPHENYL) TETRAHYDROFURAN-3 -YL) METHOXY) -3-METHYLPHENYL) PIPERAZIN-1-YL) -N- (2-HYDROXYCYCLOHEXYL) BENZAMIDE OR A PHARMACEUTICAL ACCEPTABLE SALT THEREOF
WO2017093491A1 (en) * 2015-12-04 2017-06-08 Pulmocide Limited Antimycotic triazole compound
EP3538079A4 (en) * 2016-11-28 2020-03-04 Cellix Bio Private Limited Compositions and methods for the treatment of oral infectious diseases
US11185548B2 (en) 2016-12-23 2021-11-30 Helmholtz Zentrum Munchen—Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) Inhibitors of cytochrome P450 family 7 subfamily B member 1 (CYP7B1) for use in treating diseases
GB201917867D0 (en) 2019-12-06 2020-01-22 Pulmocide Ltd Polymorphs
EP3858357A1 (en) * 2020-01-28 2021-08-04 Diaccurate Use of azole compounds to stimulate the immune system and as inhibitors for s-pla2gib
RU2770598C1 (en) * 2021-06-29 2022-04-18 Федеральное государственное автономное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет" (ПГНИУ) Application of antifungal agent based on 2-((4-r1-5-r2-3-(ethoxycarbonyl)thiophene-2-il)amino)-4-oxo-4-r3-but-2-eno acids in relation to candida aldicans

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1292472C (en) 1985-12-03 1991-11-26 Alfonsus Guilielmus Knaeps Derivatives of ¬¬4-¬4-(4-phenyl-1-piperazinyl)- phenoxymethyl|-1,3-dioxolan-2-yl|methyl|-1h-imidazoles and 1h-1,2,4-triazoles
DE3609598A1 (en) * 1986-03-21 1987-10-01 Hoechst Ag 2-AZOLYLMETHYL-2-ARYL-1,3-DIOXOLANE AND THE SALTS THEREOF, METHOD FOR THE PRODUCTION THEREOF, MEANS CONTAINING IT AND THEIR USE
JPH0717634B2 (en) 1987-11-20 1995-03-01 シェリング・コーポレーション Tri- and tetra-substituted-oxetanes and tetrahydrofuran and its intermediates
US5039676A (en) 1990-05-11 1991-08-13 Schering Corporation Tri- and tetra-substituted-oxetanes and tetrahydrofurans and intermediates thereof
US5403937A (en) * 1993-04-30 1995-04-04 Schering Corporation Process for preparing intermediates for the synthesis of antifungal agents
DE69428125T2 (en) 1993-12-21 2002-05-02 Schering Corp FUNGICIDAL TETRAHYDROFURANE
US5714490A (en) 1993-12-21 1998-02-03 Schering Corporation Tetrahydrofuran antifungals
US5486625A (en) 1994-07-08 1996-01-23 Schering Corporation Process for the preparation of chiral intermediates useful for the synthesis of antifungal agents
MX9701229A (en) 1995-06-02 1997-05-31 Schering Corp Tetrahydrofuran antifungals.
EP0957101A1 (en) 1998-05-14 1999-11-17 Janssen Pharmaceutica N.V. Water soluble azoles as broad-spectrum antifungals
BR0208626A (en) 2001-04-03 2004-03-09 Schering Corp Enhanced bioavailability antifungal composition
WO2009086303A2 (en) * 2007-12-21 2009-07-09 University Of Rochester Method for altering the lifespan of eukaryotic organisms
US8324385B2 (en) * 2008-10-30 2012-12-04 Madrigal Pharmaceuticals, Inc. Diacylglycerol acyltransferase inhibitors
AU2012284184B2 (en) * 2011-07-18 2017-03-09 Merck Patent Gmbh Benzamides
WO2013036866A1 (en) 2011-09-07 2013-03-14 The Johns Hopkins University Itraconazole analogs and use thereof
KR102579848B1 (en) 2014-12-05 2023-09-18 풀모사이드 리미티드 Antimycotic compound

Also Published As

Publication number Publication date
PL3227277T3 (en) 2020-08-10
EP3227278A1 (en) 2017-10-11
US11008307B2 (en) 2021-05-18
ES2790875T3 (en) 2020-10-29
US20210048874A1 (en) 2021-02-18
BR112017008481B1 (en) 2022-09-06
US20190023697A1 (en) 2019-01-24
IL251631A0 (en) 2017-06-29
US10450304B2 (en) 2019-10-22
US20210238169A1 (en) 2021-08-05
US10106531B2 (en) 2018-10-23
CA2963625C (en) 2023-08-22
US10487073B2 (en) 2019-11-26
PT3227277T (en) 2020-04-14
CN107001343A (en) 2017-08-01
US20170320858A1 (en) 2017-11-09
HUE048905T2 (en) 2020-08-28
EA201791174A1 (en) 2017-10-31
MX370412B (en) 2019-12-11
US20200002320A1 (en) 2020-01-02
BR112017008481A2 (en) 2018-01-09
US20190023696A1 (en) 2019-01-24
AU2015356795B2 (en) 2020-01-16
US11661415B2 (en) 2023-05-30
HK1244795A1 (en) 2018-08-17
KR102579848B1 (en) 2023-09-18
US10344022B2 (en) 2019-07-09
US10093659B2 (en) 2018-10-09
US20230295133A1 (en) 2023-09-21
IL251631B (en) 2020-05-31
SG11201702835RA (en) 2017-05-30
US10800762B2 (en) 2020-10-13
EP3227277A1 (en) 2017-10-11
US10662179B2 (en) 2020-05-26
HUE048685T2 (en) 2020-07-28
WO2016087878A1 (en) 2016-06-09
EP3227277B1 (en) 2020-02-05
DK3227278T3 (en) 2020-04-27
EA033736B1 (en) 2019-11-20
US20190276441A1 (en) 2019-09-12
US10858345B2 (en) 2020-12-08
EP3227278B1 (en) 2020-02-05
NZ730861A (en) 2021-04-30
ES2786374T3 (en) 2020-10-09
US20200239453A1 (en) 2020-07-30
WO2016087880A1 (en) 2016-06-09
US20170037035A1 (en) 2017-02-09
KR20170088850A (en) 2017-08-02
CN107001343B (en) 2020-12-11
JP2017536385A (en) 2017-12-07
JP6666345B2 (en) 2020-03-13
MX2017007188A (en) 2017-08-28
CN112375073B (en) 2024-04-16
AU2015356795A1 (en) 2017-04-27
US20200399253A1 (en) 2020-12-24
JP2017536382A (en) 2017-12-07
CN112375073A (en) 2021-02-19
JP6669751B2 (en) 2020-03-18
CA2963625A1 (en) 2016-06-09
US20200031809A1 (en) 2020-01-30

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