DK3201317T3 - BIOMARKETORS FOR RHEUMATOID ARTHRITIS AND USE THEREOF - Google Patents

BIOMARKETORS FOR RHEUMATOID ARTHRITIS AND USE THEREOF Download PDF

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Publication number
DK3201317T3
DK3201317T3 DK15847187.0T DK15847187T DK3201317T3 DK 3201317 T3 DK3201317 T3 DK 3201317T3 DK 15847187 T DK15847187 T DK 15847187T DK 3201317 T3 DK3201317 T3 DK 3201317T3
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DK
Denmark
Prior art keywords
biomarketors
rheumatoid arthritis
rheumatoid
arthritis
Prior art date
Application number
DK15847187.0T
Other languages
Danish (da)
Inventor
Qiang Feng
Dongya Zhang
Huijue Jia
Donghui Wang
Jun Wang
Original Assignee
Bgi Shenzhen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/CN2014/088069 external-priority patent/WO2016049937A1/en
Priority claimed from PCT/CN2014/088068 external-priority patent/WO2016049936A1/en
Priority claimed from PCT/CN2014/088060 external-priority patent/WO2016049930A1/en
Application filed by Bgi Shenzhen filed Critical Bgi Shenzhen
Application granted granted Critical
Publication of DK3201317T3 publication Critical patent/DK3201317T3/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/335Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Lactobacillus (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
DK15847187.0T 2014-09-30 2015-07-07 BIOMARKETORS FOR RHEUMATOID ARTHRITIS AND USE THEREOF DK3201317T3 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/CN2014/088069 WO2016049937A1 (en) 2014-09-30 2014-09-30 Biomarkers for rheumatoid arthritis and usage therof
PCT/CN2014/088068 WO2016049936A1 (en) 2014-09-30 2014-09-30 Biomarkers for rheumatoid arthritis and usage therof
PCT/CN2014/088060 WO2016049930A1 (en) 2014-09-30 2014-09-30 Biomarkers for rheumatoid arthritis and usage therof
PCT/CN2015/083488 WO2016050110A1 (en) 2014-09-30 2015-07-07 Biomarkers for rheumatoid arthritis and usage thereof

Publications (1)

Publication Number Publication Date
DK3201317T3 true DK3201317T3 (en) 2020-01-20

Family

ID=55629412

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15847187.0T DK3201317T3 (en) 2014-09-30 2015-07-07 BIOMARKETORS FOR RHEUMATOID ARTHRITIS AND USE THEREOF

Country Status (11)

Country Link
US (1) US10883146B2 (en)
EP (1) EP3201317B1 (en)
JP (1) JP6485843B2 (en)
KR (1) KR101986442B1 (en)
CN (2) CN108064263B (en)
AU (1) AU2015327511B2 (en)
CA (1) CA2963013C (en)
DK (1) DK3201317T3 (en)
HK (2) HK1248764A1 (en)
RU (1) RU2691375C2 (en)
WO (2) WO2016050110A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11514289B1 (en) * 2016-03-09 2022-11-29 Freenome Holdings, Inc. Generating machine learning models using genetic data
WO2019071516A1 (en) * 2017-10-12 2019-04-18 Perfect (China) Co., Ltd. Biomarkers for chronic hepatitis b and use thereof
CN108034708B (en) * 2017-12-14 2020-05-22 中国中医科学院中药研究所 System for determining individual effectiveness of tripterygium glycosides tablet in treating rheumatoid arthritis through expression quantity of multiple mRNA
CN109065168B (en) * 2018-08-29 2021-09-14 昆明理工大学 Method for evaluating disease risk based on spatio-temporal clustering statistics
CN111161794B (en) * 2018-12-30 2024-03-22 深圳碳云智能数字生命健康管理有限公司 Intestinal microorganism sequencing data processing method, device, storage medium and processor
CN111161795A (en) * 2019-01-15 2020-05-15 深圳碳云智能数字生命健康管理有限公司 Intestinal microorganism sequencing data processing method and device, storage medium and processor
JP2021010343A (en) * 2019-07-08 2021-02-04 三菱ケミカル株式会社 Health condition prediction method by oral cavity bacteria
CN113488107B (en) * 2021-07-07 2022-07-19 广州华银康医疗集团股份有限公司 Method, apparatus and storage medium for screening immunohistochemical library sequencing biomarkers
CN114369671A (en) * 2021-11-25 2022-04-19 上海锐翌生物科技有限公司 Marker microorganism for rheumatic arthritis and application thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20030274A1 (en) * 2001-07-26 2003-05-08 Alimentary Health Ltd LACTOBACILLUS SALIVARIUS STRAINS
RU2362808C1 (en) * 2008-02-13 2009-07-27 Государственное образовательное учреждение дополнительного профессионального образования Российская медицинская академия последипломного образования Федерального агентства по здравоохранению и социальному развитию (ГОУ ДПО РМАПО Росздрава) Way of diagnostics of microbiota disbalance of various human biotopes and degree of its expression
CN101886132B (en) * 2009-07-15 2013-09-18 北京百迈客生物科技有限公司 Method for screening molecular markers correlative with properties based on sequencing technique and BSA (Bulked Segregant Analysis) technique
CN101921748B (en) * 2010-06-30 2012-11-14 上海华大基因科技有限公司 DNA molecular label for high-throughput detection of human papilloma virus
RU2014123511A (en) * 2011-11-10 2015-12-20 Дженентек, Инк METHODS FOR TREATING, DIAGNOSTIC AND MONITORING ALZHEIMER'S DISEASE
JP5863035B2 (en) * 2012-03-07 2016-02-16 国立大学法人 東京大学 Method for detecting inflammatory bowel disease and method for examining human salivary bacterial flora
US20150211053A1 (en) * 2012-08-01 2015-07-30 Bgi-Shenzhen Biomarkers for diabetes and usages thereof
WO2014019180A1 (en) * 2012-08-01 2014-02-06 深圳华大基因研究院 Method and system for determining biomarker in abnormal state

Also Published As

Publication number Publication date
CN108064272A (en) 2018-05-22
CN108064272B (en) 2021-07-09
US20170226565A1 (en) 2017-08-10
RU2691375C2 (en) 2019-06-11
EP3201317A1 (en) 2017-08-09
CA2963013C (en) 2022-10-04
CA2963013A1 (en) 2016-04-07
RU2017115001A3 (en) 2018-11-05
HK1248753A1 (en) 2018-10-19
HK1248764A1 (en) 2018-10-19
KR20170063879A (en) 2017-06-08
RU2017115001A (en) 2018-11-05
CN108064263B (en) 2022-04-26
KR101986442B1 (en) 2019-06-05
US10883146B2 (en) 2021-01-05
AU2015327511B2 (en) 2018-12-06
JP2017530708A (en) 2017-10-19
WO2016050110A1 (en) 2016-04-07
JP6485843B2 (en) 2019-03-20
WO2016050111A1 (en) 2016-04-07
CN108064263A (en) 2018-05-22
EP3201317B1 (en) 2019-12-11
EP3201317A4 (en) 2017-08-09
AU2015327511A1 (en) 2017-04-20

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