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Application filed by Nippon Kayaku KkfiledCriticalNippon Kayaku Kk
Priority to DK312885ApriorityCriticalpatent/DK154220C/en
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Publication of DK312885ApublicationCriticalpatent/DK312885A/en
Publication of DK154220BpublicationCriticalpatent/DK154220B/en
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Publication of DK154220CpublicationCriticalpatent/DK154220C/en
A process for preparing etoposide in which a 4'- halogenoacetyl-4'-demethylepipodophyllotoxin-β-D-2,3- di-O-halogenoacetyl-4,6-O-ethylidene glucoside of the general formula: <IMAGE> in which R1 and R2, which can be identical or different, each denote -COCHX2 or -COCX3, in which X denotes a halogen atom, with an alcohol, an amine and/or ammonia for removing the halogenoacetyl groups, can be carried out in one step and yields etoposide with only a very small content of impurities.
DK312885A1985-07-091985-07-09
PROCEDURE FOR PREPARING ETHOPOSIDE
DK154220C
(en)