DK2936164T3 - Automatisering af inkubering, behandling, høst og analyse af prøver i en multicelleplade med en tyndfilmstøtte til prøven - Google Patents

Automatisering af inkubering, behandling, høst og analyse af prøver i en multicelleplade med en tyndfilmstøtte til prøven Download PDF

Info

Publication number
DK2936164T3
DK2936164T3 DK13811205.7T DK13811205T DK2936164T3 DK 2936164 T3 DK2936164 T3 DK 2936164T3 DK 13811205 T DK13811205 T DK 13811205T DK 2936164 T3 DK2936164 T3 DK 2936164T3
Authority
DK
Denmark
Prior art keywords
multicelle
thinfilm
harvesting
incubation
automation
Prior art date
Application number
DK13811205.7T
Other languages
English (en)
Inventor
Florent Cipriani
Jose Antonio Marquez
Original Assignee
European Molecular Biology Laboratory Embl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by European Molecular Biology Laboratory Embl filed Critical European Molecular Biology Laboratory Embl
Application granted granted Critical
Publication of DK2936164T3 publication Critical patent/DK2936164T3/da

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/06—Crystallising dishes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50853—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates with covers or lids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/12—Well or multiwell plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04—Cell isolation or sorting
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/028—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having reaction cells in the form of microtitration plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1079—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices with means for piercing stoppers or septums
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/025—Align devices or objects to ensure defined positions relative to each other
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/044—Connecting closures to device or container pierceable, e.g. films, membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0893—Geometry, shape and general structure having a very large number of wells, microfabricated wells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N2001/045—Laser ablation; Microwave vaporisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0401—Sample carriers, cuvettes or reaction vessels
    • G01N2035/0403—Sample carriers with closing or sealing means

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Robotics (AREA)
  • Computer Hardware Design (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
DK13811205.7T 2012-12-18 2013-12-18 Automatisering af inkubering, behandling, høst og analyse af prøver i en multicelleplade med en tyndfilmstøtte til prøven DK2936164T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261738506P 2012-12-18 2012-12-18
PCT/EP2013/077171 WO2014096055A1 (en) 2012-12-18 2013-12-18 Automation of incubation, processing, harvesting and analysis of samples in a multi-cell plate with thin film sample support

Publications (1)

Publication Number Publication Date
DK2936164T3 true DK2936164T3 (da) 2020-04-06

Family

ID=49841671

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13811205.7T DK2936164T3 (da) 2012-12-18 2013-12-18 Automatisering af inkubering, behandling, høst og analyse af prøver i en multicelleplade med en tyndfilmstøtte til prøven

Country Status (6)

Country Link
US (1) US9731289B2 (da)
EP (1) EP2936164B1 (da)
DK (1) DK2936164T3 (da)
ES (1) ES2783830T3 (da)
PT (1) PT2936164T (da)
WO (1) WO2014096055A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9869648B2 (en) * 2014-06-26 2018-01-16 The Board Of Trustees Of The Leland Stanford Junior University High density grids
EP3037518B1 (en) 2014-12-28 2020-05-06 Femtobiomed Inc. Device for putting material into cell
PL234772B1 (pl) * 2018-01-17 2020-03-31 Univ Przyrodniczy W Lublinie Przyrząd do wycinania próbek z cienkowarstwowych materiałów biologicznych i syntetycznych
EP3567362B1 (de) * 2018-05-09 2022-03-30 Euroimmun Medizinische Labordiagnostika AG Verfahren und vorrichtung zur segmentierung und vereinzelung flächig verteilter proben mittels laserschneidens
US10775395B2 (en) * 2018-10-18 2020-09-15 Arctoris Limited System and method of performing a biological experiment with adaptive cybernetic control of procedural conditions
WO2020176798A1 (en) 2019-02-27 2020-09-03 Synthego Corporation Cell culture laser photoablation

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6913732B2 (en) * 2001-03-19 2005-07-05 Corning Incorporated Microplate for performing crystallography studies and methods for making and using such microplates
US7332029B2 (en) * 2002-01-18 2008-02-19 Neuro Probe Incorporated Crystal forming apparatus and method for using same
AU2003228482A1 (en) 2002-04-10 2003-10-27 Kendro Laboratoryb Products, Lp Automated protein crystallization imaging
US20040096368A1 (en) * 2002-06-28 2004-05-20 Igen International, Inc. Assay systems and components
US7112241B2 (en) * 2002-12-31 2006-09-26 Corning Incorporated Protein crystallography hanging drop multiwell plate
JP2005077308A (ja) 2003-09-02 2005-03-24 Corona Giken Kogyo Kk 検体トレー、及び検体トレーの使用方法
US7251398B2 (en) * 2004-08-26 2007-07-31 Interuniversitair Microelektronica Centrum (Imec) Method for providing an optical interface and devices according to such methods
EP1859284A1 (de) * 2005-03-17 2007-11-28 Kuoni, A. Vorrichtung und verfahren zum aufbringen einer vielzahl von mikrotröpfchen auf ein substrat
US7807108B2 (en) * 2006-09-18 2010-10-05 Leica Microsystems Cms Gmbh Apparatus for receiving biological specimens
US7974380B2 (en) * 2007-05-09 2011-07-05 Fluidigm Corporation Method and system for crystallization and X-ray diffraction screening

Also Published As

Publication number Publication date
EP2936164B1 (en) 2020-01-15
US20150321190A1 (en) 2015-11-12
US9731289B2 (en) 2017-08-15
ES2783830T3 (es) 2020-09-18
EP2936164A1 (en) 2015-10-28
PT2936164T (pt) 2020-04-22
WO2014096055A1 (en) 2014-06-26

Similar Documents

Publication Publication Date Title
DK2836826T3 (da) Prøveudtagningsplade til en elektrisk impedanshæmatokrit og HBA1C-biosensor
DK2472265T3 (da) Automatiseret system og fremgangsmåde til forarbejdning af biologiske prøver
DK2989470T3 (da) Indretning og fremgangsmåde til automatisk behandling af kulturplader til mikrobiologiske prøver
DK2936164T3 (da) Automatisering af inkubering, behandling, høst og analyse af prøver i en multicelleplade med en tyndfilmstøtte til prøven
DK2836609T4 (da) Sammensætninger og fremgangsmåder til kvantificering af en nucleinsyresekvens i en prøve
BR112014027450A2 (pt) aparelho e métodos de análise microbiológica
DK3080585T3 (da) Biosensorer til biologisk eller kemisk analyse og fremgangsmåder til fremstilling heraf
DK3327141T3 (da) Fremgangsmåde til identificering af den cellulære sammensætning i en biologisk prøve
EP2784513A4 (en) CHIP FOR SAMPLE ANALYSIS, SAMPLE ANALYSIS METHOD, AND GENE ANALYSIS METHOD
EP2693219A4 (en) Sample Analysis System and Sample Analysis Device
EP3023786A4 (en) Blood analysis method, control device, and blood cell analyzer
GB201601244D0 (en) Flow cell for nucleic acid analysis and nucleic acid analyzer
EP2703813A4 (en) BLOOD ANALYZER, BLOOD ANALYSIS METHOD, AND COMPUTER PROGRAM
DK2676139T3 (da) Fremgangsmåde til diagnosticering af cancer og diagnosekit til måling af nk celle-aktivitet
EP2703494A4 (en) CELL ANALYSIS METHOD, DEVICE AND PROGRAM
EP2995676A4 (en) DEVICE FOR ANALYZING CELLS AND FOR MONITORING CELL CULTURE AND METHOD FOR ANALYZING CELLS AND MONITORING CELL CULTURE USING THE SAME
DK2609194T3 (da) Fremgangsmåder til berigelse af pluripotente stamcelle-afledte kardiomyocyt-progenitorceller og kardiomyocytceller baseret på SIRPA-ekspression
EP2927694A4 (en) AUTOMATIC ANALYZER AND AUTOMATIC ANALYSIS METHOD
BR112013019162A2 (pt) método de análise e dispositivo de leitura de microarranjo
EP3014647A4 (en) MASS SPECTROMETRY ANALYSIS OF MICROORGANISMS IN SAMPLES
EP2963418A4 (en) DEVICE AND METHOD FOR ANALYZING URINE SAMPLES
EP2724668A4 (en) DEVICE FOR THE ANALYSIS OF PSYCHICAL DISEASES, METHOD FOR THE ANALYSIS OF PSYCHICAL DISEASES AND PROGRAM THEREFOR
DK2751725T3 (da) Anvendelse af kernemagnetisk resonans og nær-infrarød til analyse af biologiske prøver
EP2708880A4 (en) DEVICE FOR MEASURING A BIOLOGICAL SAMPLE AND METHOD OF MEASURING A BIOLOGICAL SAMPLE USING THE SAME
DK2579042T3 (da) Fremgangsmåde til at påvise Aß-specifikke antistoffer i en biologisk prøve