DK2847188T3 - Makrocykliske picolinamides som fungicider - Google Patents

Makrocykliske picolinamides som fungicider Download PDF

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Publication number
DK2847188T3
DK2847188T3 DK13788029.0T DK13788029T DK2847188T3 DK 2847188 T3 DK2847188 T3 DK 2847188T3 DK 13788029 T DK13788029 T DK 13788029T DK 2847188 T3 DK2847188 T3 DK 2847188T3
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DK
Denmark
Prior art keywords
compounds
compound
methyl
benzyl
alkyl
Prior art date
Application number
DK13788029.0T
Other languages
English (en)
Inventor
Kevin G Meyer
James M Renga
Benjamin M Nugent
Fangzheng Li
W John Owen
Chenglin Yao
Jeremy Wilmot
Karla Bravo-Altamirano
Original Assignee
Dow Agrosciences Llc
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Application filed by Dow Agrosciences Llc filed Critical Dow Agrosciences Llc
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Publication of DK2847188T3 publication Critical patent/DK2847188T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/24—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/18—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, directly attached to a heterocyclic or cycloaliphatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Claims (15)

1. Forbindelse med formlen I:
X er H eller C(0)R6; Y er H, C(0)R6 eller Q; Q er
Ri er O; R2 er H, alkyl, alkenyl, aryl, heterocyclyl, silyl, hver substitueret med 0, 1 eller flere R5, eller -C(0)R5; R3 er phenyl eller cyclohexyl; R4 er alkyl eller alkoxy, der er substitueret med 0, 1 eller flere R5; R5 er hydroxy, alkyl, alkenyl, halogen, halogenalkyl, alkoxy, halogenalkoxy, C(0)R8, arylalkoxy, eller aryl, hvor hvert R5 er substitueret med 0, 1 eller flere R9; R6 er alkoxy, benzyloxy, substitueret med 0, 1 eller flere Rg; R7 er H, -C(0)R4 eller -CH20C(0)R4; R8 er hydroxy, alkyl, alkoxy, N(R9)2, eller arylalkoxy; og R9 er H eller alkyl.
2. Forbindelsen ifølge krav 1, hvor X er H, og Y er Q.
3. Forbindelsen ifølge krav 2, hvor R2 er uafhængigt valgt blandt alkyl eller aryl hver substitueret med 0, 1 eller flere R5, eller-C(0)R5.
4. Forbindelsen ifølge krav 3, hvor R3 er phenyl.
5. Forbindelsen ifølge krav 4, hvor R4 er alkyl substitueret med 0, 1 eller flere r5.
6. Forbindelsen ifølge krav 5, hvor R5 er alkyl, aryl, alkoxy eller halogen.
7. Forbindelsen ifølge krav 1, hvor X og Y uafhængigt er valgt blandt H eller C(0)R6.
8. Forbindelsen ifølge krav 7, hvor R2 uafhængigt er valgt blandt H, alkyl, alkenyl, aryl, heterocyclyl, silyl, hver substitueret med 0, 1 eller flere R5, -C(0)R5.
9. Forbindelsen ifølge krav 8, hvor R3 uafhængigt er phenyl eller cyclohexyl.
10. Forbindelsen ifølge krav 9, hvor R5 er alkyl eller aryl substitueret med 0, 1 eller flere Rg.
11. Forbindelsen ifølge krav 10, hvor R6 er alkoxy eller benzyloxy substitueret med 0, 1 eller flere Rg.
12. Forbindelsen ifølge krav 11, hvor Rg er hydrogen eller alkyl.
13. Sammensætning til bekæmpelse af etfungalt patogen, der indbefatter: (a) mindst en af forbindelserne ifølge krav 1-12 og et fytologisk acceptabelt bæremateriale; eller (b) blandinger af mindst en af forbindelserne ifølge krav 1-12 med andre pesticider, der indbefatter fungicider, insekticider, nematocider, miticider, arthropodicider, baktericider og kombinationer deraf.
14. Sammensætning ifølge krav 13, hvor det fungale patogen er: (a) mindst en af bladpletskimmel på hvede (Mycosphaerella graminicola·, anamorf: Septoria tritici), brunrust på hvede (Puccinia triticina), striberust på hvede (Puccinia striiformis), æbleskurv (Venturia inaequalis), majsbrand (Ustilago maydis), meldug på vinranke (Uncinula necator), skoldplet på byg {Rhynchosporium secalis), brunsyge på ris (Magnaporthe grisea), falskmeldug på agurker (Pseudoperonospora cubensis), rust på sojabønne (Phakopsora pachyrhizi), brunplet på hvede (Leptosphaeria nodorum), ægtemeldug på hvede (Blumeria graminis f. sp.tritici), ægtemeldug på byg (Blumeria graminis f. sp. hordei), ægtemeldug på agurker (Erysiphe cichoracearum), sortbrand på agurker (Glomerella lagenarium), bladpletter på sukkerroer (Cercospora beticola), tørpletsyge på tomat (Alternaria solani), og bladpletsyge på byg (Pyrenophora teres)·, eller (b) mindst en af bladpletskimmel på hvede (Septoria tritici), brunrust på hvede {Puccinia triticina), og rust på sojabønne (Phakopsora pachyrhizi).
15. Fremgangsmåde til bekæmpelse og forebyggelse af svampeangreb på en plante, hvilken fremgangsmåde indbefatter følgende trin: at anvende en fungicidt effektiv mængde af mindst en af forbindelserne af kravene 1-12 eller mindst en af sammensætningerne ifølge krav 13 til mindst en af planten, et område i nærheden af planten, jord tilpasset til at understøtte væksten af planten, en rod af planten, og løvet af planten.
DK13788029.0T 2012-05-07 2013-05-06 Makrocykliske picolinamides som fungicider DK2847188T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261643653P 2012-05-07 2012-05-07
PCT/US2013/039729 WO2013169660A1 (en) 2012-05-07 2013-05-06 Macrocyclic picolinamides as fungicides

Publications (1)

Publication Number Publication Date
DK2847188T3 true DK2847188T3 (da) 2017-04-03

Family

ID=49513006

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Application Number Title Priority Date Filing Date
DK13788029.0T DK2847188T3 (da) 2012-05-07 2013-05-06 Makrocykliske picolinamides som fungicider

Country Status (21)

Country Link
US (1) US8835462B2 (da)
EP (1) EP2847188B1 (da)
JP (1) JP2015517497A (da)
KR (1) KR20150013692A (da)
CN (1) CN104411705B (da)
AR (1) AR090966A1 (da)
AU (1) AU2013259789A1 (da)
BR (1) BR112014027673A2 (da)
CA (1) CA2872034A1 (da)
CL (1) CL2014003008A1 (da)
CO (1) CO7151548A2 (da)
CR (1) CR20140499A (da)
DK (1) DK2847188T3 (da)
EC (1) ECSP14027269A (da)
HK (1) HK1208034A1 (da)
IL (1) IL235384A0 (da)
MX (1) MX2014013642A (da)
PL (1) PL2847188T3 (da)
RU (1) RU2014149194A (da)
UY (1) UY34790A (da)
WO (1) WO2013169660A1 (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3153020B1 (en) 2009-10-07 2018-11-28 Dow AgroSciences LLC Synergistic fungicidial mixtures for fungal control in cereals
ES2666144T3 (es) 2012-12-28 2018-05-03 Dow Agrosciences Llc Mezclas fungicidas sinérgicas para control fúngico en cereales
PL2938190T3 (pl) 2012-12-31 2018-05-30 Dow Agrosciences Llc Makrocykliczne pikolinamidy jako fungicydy
CN105705502A (zh) 2013-10-01 2016-06-22 美国陶氏益农公司 具有杀真菌活性的大环吡啶酰胺化合物
US9439422B2 (en) 2013-10-01 2016-09-13 Dow Agrosciences Llc Use of macrocyclic picolinamides as fungicides
US9247741B2 (en) 2013-12-26 2016-02-02 Dow Agrosciences Llc Use of macrocyclic picolinamides as fungicides
US9549556B2 (en) 2013-12-26 2017-01-24 Dow Agrosciences Llc Macrocyclic picolinamides as fungicides
CN106061260A (zh) 2013-12-31 2016-10-26 美国陶氏益农公司 用于谷类中真菌防治的协同杀真菌混合物
US20150322051A1 (en) * 2014-05-06 2015-11-12 Dow Agrosciences Llc Macrocyclic picolinamides as fungicides
EP3166936A4 (en) * 2014-07-08 2017-11-22 Dow AgroSciences LLC Macrocyclic picolinamides as fungicides
BR112017000104A2 (pt) * 2014-07-08 2017-10-31 Dow Agrosciences Llc picolinamidas macrocíclicas como fungicidas
JP6513178B2 (ja) 2014-07-08 2019-05-15 ダウ アグロサイエンシィズ エルエルシー ４−アルコキシ−３−ヒドロキシピコリン酸の製造方法
CN106660959B (zh) 2014-07-08 2019-12-03 美国陶氏益农公司 3-羟基吡啶甲酸的制备方法
WO2016069370A1 (en) * 2014-10-28 2016-05-06 Dow Agrosciences Llc Macrocyclic picolinamides as fungicides
AU2015374458B2 (en) * 2014-12-30 2018-02-15 Dow Agrosciences Llc Use of picolinamide compounds with fungicidal activity
RU2703402C2 (ru) * 2014-12-30 2019-10-16 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи Пиколинамиды с фунгицидной активностью
CA2972405A1 (en) 2014-12-30 2016-07-07 Dow Agrosciences Llc Use of picolinamide compounds as fungicides
RU2702697C2 (ru) * 2014-12-30 2019-10-09 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи Использование пиколинамидных соединений с фунгицидной активностью
WO2016109305A1 (en) 2014-12-30 2016-07-07 Dow Agrosciences Llc Use of picolinamides as fungicides
CA2972091A1 (en) 2014-12-30 2016-07-07 Dow Agrosciences Llc Fungicidal compositions comprising a derivative of uk-2a
US10231452B2 (en) 2016-08-30 2019-03-19 Dow Agrosciences Llc Thiopicolinamide compounds with fungicidal activity
WO2018045003A1 (en) 2016-08-30 2018-03-08 Dow Agrosciences Llc Picolinamide n-oxide compounds with fungicidal activity
WO2018044996A1 (en) 2016-08-30 2018-03-08 Dow Agrosciences Llc Picolinamides as fungicides
US10334852B2 (en) 2016-08-30 2019-07-02 Dow Agrosciences Llc Pyrido-1,3-oxazine-2,4-dione compounds with fungicidal activity
BR102018000183B1 (pt) 2017-01-05 2023-04-25 Dow Agrosciences Llc Picolinamidas, composição para controle de um patógeno fúngico, e método para controle e prevenção de um ataque por fungos em uma planta
EP3618626A4 (en) 2017-05-02 2020-12-02 Dow Agrosciences LLC USE OF AN ACYCLIC PICOLINAMIDE COMPOUND AS A FUNGICIDE FOR FUNGAL GRASS INFESTATION
TW201842851A (zh) 2017-05-02 2018-12-16 美商陶氏農業科學公司 用於穀類中的真菌防治之協同性混合物
TWI774761B (zh) 2017-05-02 2022-08-21 美商科迪華農業科技有限責任公司 用於穀物中的真菌防治之協同性混合物
BR102019004480B1 (pt) 2018-03-08 2023-03-28 Dow Agrosciences Llc Picolinamidas como fungicidas
CA3115684A1 (en) 2018-10-15 2020-04-23 Dow Agrosciences Llc Methods for sythesis of oxypicolinamides

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CZ2002487A3 (cs) * 1999-08-20 2002-06-12 Dow Agrosciences Llc Fungicidní heterocyklické aromatické amidy, prostředky na jejich bázi, způsoby jejich pouľití a přípravy
AR037328A1 (es) * 2001-10-23 2004-11-03 Dow Agrosciences Llc Compuesto de [7-bencil-2,6-dioxo-1,5-dioxonan-3-il]-4-metoxipiridin-2-carboxamida, composicion que lo comprende y metodo que lo utiliza
EP3153020B1 (en) * 2009-10-07 2018-11-28 Dow AgroSciences LLC Synergistic fungicidial mixtures for fungal control in cereals
WO2012070015A1 (en) * 2010-11-24 2012-05-31 Stemergie Biotechnology Sa Inhibitors of the activity of complex iii of the mitochondrial electron transport chain and use thereof for treating diseases

Also Published As

Publication number Publication date
UY34790A (es) 2013-12-31
EP2847188A1 (en) 2015-03-18
ECSP14027269A (es) 2015-09-30
CR20140499A (es) 2014-12-01
RU2014149194A (ru) 2016-06-27
JP2015517497A (ja) 2015-06-22
MX2014013642A (es) 2015-03-03
CA2872034A1 (en) 2013-11-14
US20130296373A1 (en) 2013-11-07
IL235384A0 (en) 2014-12-31
WO2013169660A1 (en) 2013-11-14
AU2013259789A1 (en) 2014-11-06
HK1208034A1 (en) 2016-02-19
PL2847188T3 (pl) 2017-07-31
EP2847188A4 (en) 2015-11-18
CL2014003008A1 (es) 2015-01-16
CO7151548A2 (es) 2014-12-29
CN104411705A (zh) 2015-03-11
AR090966A1 (es) 2014-12-17
US8835462B2 (en) 2014-09-16
CN104411705B (zh) 2017-04-19
KR20150013692A (ko) 2015-02-05
BR112014027673A2 (pt) 2017-06-27
EP2847188B1 (en) 2016-12-21

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