DK2831105T3 - Tgf-type ii-type iii-receptorfusioner - Google Patents
Tgf-type ii-type iii-receptorfusionerInfo
- Publication number
- DK2831105T3 DK2831105T3 DK13768513.7T DK13768513T DK2831105T3 DK 2831105 T3 DK2831105 T3 DK 2831105T3 DK 13768513 T DK13768513 T DK 13768513T DK 2831105 T3 DK2831105 T3 DK 2831105T3
- Authority
- DK
- Denmark
- Prior art keywords
- type
- tgf
- iii receptor
- receptor fusions
- type iii
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/64—General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261616740P | 2012-03-28 | 2012-03-28 | |
| PCT/US2013/034504 WO2013149094A1 (en) | 2012-03-28 | 2013-03-28 | TGFβ TYPE II-TYPE III RECEPTOR FUSIONS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2831105T3 true DK2831105T3 (da) | 2017-11-20 |
Family
ID=49261272
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13768513.7T DK2831105T3 (da) | 2012-03-28 | 2013-03-28 | Tgf-type ii-type iii-receptorfusioner |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | USRE49280E1 (da) |
| EP (2) | EP3299388A1 (da) |
| DK (1) | DK2831105T3 (da) |
| ES (1) | ES2648492T3 (da) |
| HK (1) | HK1253015A1 (da) |
| HR (1) | HRP20171713T1 (da) |
| HU (1) | HUE034593T2 (da) |
| LT (1) | LT2831105T (da) |
| NO (1) | NO2881352T3 (da) |
| PL (1) | PL2831105T3 (da) |
| PT (1) | PT2831105T (da) |
| SI (1) | SI2831105T1 (da) |
| WO (1) | WO2013149094A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2831105T3 (da) | 2012-03-28 | 2017-11-20 | Univ Texas | Tgf-type ii-type iii-receptorfusioner |
| US20170166624A1 (en) * | 2014-07-14 | 2017-06-15 | The Board Of Regents Of The University Of Texas System | TGFß TYPE II-TYPE III RECEPTOR FUSIONS |
| MX2017012846A (es) | 2015-04-06 | 2018-11-09 | Acceleron Pharma Inc | Heteromultimeros de receptor de superfamilia de tgf-beta tipo i y tipo ii y usos de los mismos. |
| ES2864850T3 (es) | 2015-04-06 | 2021-10-14 | Acceleron Pharma Inc | Proteínas de fusión del receptor de brazo único tipo I y tipo II y uso de las mismas |
| MA41919A (fr) | 2015-04-06 | 2018-02-13 | Acceleron Pharma Inc | Hétéromultimères alk4:actriib et leurs utilisations |
| BR112019006993A2 (pt) | 2016-10-05 | 2019-09-03 | Acceleron Pharma Inc | heteromultímeros de alk4:actriib e usos dos mesmos |
| WO2018222901A1 (en) | 2017-05-31 | 2018-12-06 | Elstar Therapeutics, Inc. | Multispecific molecules that bind to myeloproliferative leukemia (mpl) protein and uses thereof |
| US20190248881A1 (en) * | 2017-12-04 | 2019-08-15 | Precithera, Inc. | TGF-ß RECEPTOR FUSION PROTEINS AND OTHER TGF-ß ANTAGONISTS FOR REDUCING TGF-ß SIGNALING |
| CN112074535B (zh) | 2018-03-09 | 2024-10-11 | 艾吉纳斯公司 | 抗cd73抗体及其使用方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4703004A (en) | 1984-01-24 | 1987-10-27 | Immunex Corporation | Synthesis of protein with an identification peptide |
| US4851341A (en) | 1986-12-19 | 1989-07-25 | Immunex Corporation | Immunoaffinity purification system |
| US5824655A (en) | 1995-02-15 | 1998-10-20 | The University Of Utah | Anti-transforming growth factor-β gene therapy |
| AU4572899A (en) | 1998-06-16 | 2000-01-05 | Biogen, Inc. | Variant type ii tgf-beta receptor fusion proteins and methods |
| US20060286105A1 (en) | 2003-04-30 | 2006-12-21 | Steven Ledbetter | Tgf-beta antagonists combined with renin-angiotensin-aldosteron-system antagonists for treating renal insufficiency |
| WO2005028517A2 (en) | 2003-05-09 | 2005-03-31 | The General Hospital Corporation | SOLUBLE TGF-β TYPE III RECEPTOR FUSION PROTEINS |
| US7786261B2 (en) | 2004-09-02 | 2010-08-31 | National Research Council Of Canada | Coiled-coil fusion proteins comprising cell receptor domains |
| US7795389B2 (en) * | 2004-09-28 | 2010-09-14 | The Board Of Regents Of The University Of Texas System | Antagonizing TGF-beta activity with various ectodomains TGF-beta receptors used in combination or as fusion proteins |
| JP2010529859A (ja) * | 2007-06-15 | 2010-09-02 | ジェンザイム、コーポレーション | ＴＧＦ−βＩＩ型受容体の２つのＴＧＦ−β結合ドメインを含有する融合タンパク質 |
| AU2008322998B2 (en) * | 2007-11-12 | 2013-10-03 | Chreto Aps | Dual affinity polypeptides for purification |
| DK2831105T3 (da) | 2012-03-28 | 2017-11-20 | Univ Texas | Tgf-type ii-type iii-receptorfusioner |
-
2013
- 2013-03-28 DK DK13768513.7T patent/DK2831105T3/da active
- 2013-03-28 EP EP17185422.7A patent/EP3299388A1/en not_active Withdrawn
- 2013-03-28 HU HUE13768513A patent/HUE034593T2/en unknown
- 2013-03-28 ES ES13768513.7T patent/ES2648492T3/es active Active
- 2013-03-28 PT PT137685137T patent/PT2831105T/pt unknown
- 2013-03-28 SI SI201330833T patent/SI2831105T1/en unknown
- 2013-03-28 WO PCT/US2013/034504 patent/WO2013149094A1/en active Application Filing
- 2013-03-28 LT LTEP13768513.7T patent/LT2831105T/lt unknown
- 2013-03-28 US US16/375,242 patent/USRE49280E1/en active Active
- 2013-03-28 US US14/387,901 patent/US9611306B2/en not_active Ceased
- 2013-03-28 EP EP13768513.7A patent/EP2831105B1/en active Active
- 2013-03-28 PL PL13768513T patent/PL2831105T3/pl unknown
-
2014
- 2014-12-04 NO NO14004101A patent/NO2881352T3/no unknown
-
2017
- 2017-11-08 HR HRP20171713TT patent/HRP20171713T1/hr unknown
-
2018
- 2018-09-27 HK HK18112391.0A patent/HK1253015A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUE034593T2 (en) | 2018-02-28 |
| US20150045299A1 (en) | 2015-02-12 |
| EP2831105A1 (en) | 2015-02-04 |
| HRP20171713T1 (hr) | 2018-01-26 |
| EP2831105B1 (en) | 2017-08-09 |
| LT2831105T (lt) | 2018-01-10 |
| NO2881352T3 (da) | 2018-06-30 |
| HK1253015A1 (zh) | 2019-06-06 |
| PT2831105T (pt) | 2017-12-06 |
| ES2648492T3 (es) | 2018-01-03 |
| EP2831105A4 (en) | 2016-01-20 |
| USRE49280E1 (en) | 2022-11-08 |
| PL2831105T3 (pl) | 2018-01-31 |
| WO2013149094A1 (en) | 2013-10-03 |
| US9611306B2 (en) | 2017-04-04 |
| SI2831105T1 (en) | 2018-03-30 |
| EP3299388A1 (en) | 2018-03-28 |
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