DK2819516T3 - Anvendelse af (1r,5s)-(+)-1-(naphthalen-2-yl)-3-azabicyclo{3.1.0}hexan i behandlingen af lidelser forbundet med monoamin-neurotransmittere - Google Patents
Anvendelse af (1r,5s)-(+)-1-(naphthalen-2-yl)-3-azabicyclo{3.1.0}hexan i behandlingen af lidelser forbundet med monoamin-neurotransmittere Download PDFInfo
- Publication number
- DK2819516T3 DK2819516T3 DK12820058.1T DK12820058T DK2819516T3 DK 2819516 T3 DK2819516 T3 DK 2819516T3 DK 12820058 T DK12820058 T DK 12820058T DK 2819516 T3 DK2819516 T3 DK 2819516T3
- Authority
- DK
- Denmark
- Prior art keywords
- hexan
- naphthalen
- azabicyclo
- treatment
- monoamine neurotransmitters
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161574231P | 2011-07-30 | 2011-07-30 | |
| US201113334066A | 2011-12-22 | 2011-12-22 | |
| US201213528940A | 2012-06-21 | 2012-06-21 | |
| PCT/US2012/000335 WO2013019271A1 (en) | 2011-07-30 | 2012-07-27 | Use of (1r,5s)-(+)-1-(naphthalen-2-yl)-3-azabicyclo{3.1.0}hexane in the treatment of conditions affected by monoamine neurotransmitters |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2819516T3 true DK2819516T3 (da) | 2020-03-16 |
Family
ID=47629575
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK12820058.1T DK2819516T3 (da) | 2011-07-30 | 2012-07-27 | Anvendelse af (1r,5s)-(+)-1-(naphthalen-2-yl)-3-azabicyclo{3.1.0}hexan i behandlingen af lidelser forbundet med monoamin-neurotransmittere |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP2819516B1 (da) |
| CA (1) | CA2843847C (da) |
| CY (1) | CY1122773T1 (da) |
| DK (1) | DK2819516T3 (da) |
| ES (1) | ES2779032T3 (da) |
| HR (1) | HRP20200424T1 (da) |
| HU (1) | HUE048715T2 (da) |
| LT (1) | LT2819516T (da) |
| PL (1) | PL2819516T3 (da) |
| PT (1) | PT2819516T (da) |
| SI (1) | SI2819516T1 (da) |
| WO (1) | WO2013019271A1 (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2719384B1 (en) | 2005-07-27 | 2018-08-08 | Otsuka America Pharmaceutical, Inc. | Novel 1-naphthyl-3-azabicyclo[3.1.0]hexanes:preparation and use to treat neuropsychiatric disorders |
| US9133159B2 (en) | 2007-06-06 | 2015-09-15 | Neurovance, Inc. | 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments |
| US20160303077A1 (en) * | 2013-12-09 | 2016-10-20 | Neurovance, Inc. | Novel compositions |
| EP3310352A4 (en) | 2015-06-17 | 2019-03-13 | Otsuka America Pharmaceutical, Inc. | CRYSTALLINE COMPOUNDS |
| US11701323B2 (en) | 2016-06-28 | 2023-07-18 | Trichomeshell Ltd. | Dosage form for vaporization and smoking |
| WO2018119291A1 (en) * | 2016-12-21 | 2018-06-28 | Otsuka America Pharmaceutical, Inc. | Synthetic methods |
| WO2024048782A1 (en) | 2022-09-02 | 2024-03-07 | Otsuka Pharmaceutical Co., Ltd. | 1-(naphthalen-2-yl)-3-azabicyclo[3.1.0]hexane for treating major depressive disorder |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6204284B1 (en) * | 1991-12-20 | 2001-03-20 | American Cyanamid Company | Use of 1-(substitutedphenyl)-3-azabicyclo[3.1.0]hexanes for the treatment of chemical dependencies |
| US6569887B2 (en) * | 2001-08-24 | 2003-05-27 | Dov Pharmaceuticals Inc. | (−)-1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as a dopamine-reuptake |
| EP1482921A1 (en) * | 2002-02-12 | 2004-12-08 | Cypress Bioscience, Inc. | Methods of treating attention deficit/hyperactivity disorder (adhd) |
| EP2719384B1 (en) * | 2005-07-27 | 2018-08-08 | Otsuka America Pharmaceutical, Inc. | Novel 1-naphthyl-3-azabicyclo[3.1.0]hexanes:preparation and use to treat neuropsychiatric disorders |
-
2012
- 2012-07-27 EP EP12820058.1A patent/EP2819516B1/en active Active
- 2012-07-27 DK DK12820058.1T patent/DK2819516T3/da active
- 2012-07-27 ES ES12820058T patent/ES2779032T3/es active Active
- 2012-07-27 HU HUE12820058A patent/HUE048715T2/hu unknown
- 2012-07-27 PT PT128200581T patent/PT2819516T/pt unknown
- 2012-07-27 PL PL12820058T patent/PL2819516T3/pl unknown
- 2012-07-27 WO PCT/US2012/000335 patent/WO2013019271A1/en active Application Filing
- 2012-07-27 SI SI201231745T patent/SI2819516T1/sl unknown
- 2012-07-27 CA CA2843847A patent/CA2843847C/en active Active
- 2012-07-27 LT LTEP12820058.1T patent/LT2819516T/lt unknown
-
2020
- 2020-03-16 HR HRP20200424TT patent/HRP20200424T1/hr unknown
- 2020-03-17 CY CY20201100241T patent/CY1122773T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SI2819516T1 (sl) | 2020-07-31 |
| HRP20200424T1 (hr) | 2020-09-04 |
| LT2819516T (lt) | 2020-05-25 |
| WO2013019271A1 (en) | 2013-02-07 |
| CY1122773T1 (el) | 2021-05-05 |
| EP2819516B1 (en) | 2019-12-25 |
| CA2843847A1 (en) | 2013-02-07 |
| HUE048715T2 (hu) | 2020-09-28 |
| ES2779032T3 (es) | 2020-08-13 |
| CA2843847C (en) | 2021-05-18 |
| PT2819516T (pt) | 2020-03-25 |
| PL2819516T3 (pl) | 2020-08-10 |
| EP2819516A1 (en) | 2015-01-07 |
| EP2819516A4 (en) | 2016-01-20 |
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