DK2731650T3 - Drivmekanisme til en lægemiddelfremføringsanordning - Google Patents

Drivmekanisme til en lægemiddelfremføringsanordning Download PDF

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Publication number
DK2731650T3
DK2731650T3 DK12733747.5T DK12733747T DK2731650T3 DK 2731650 T3 DK2731650 T3 DK 2731650T3 DK 12733747 T DK12733747 T DK 12733747T DK 2731650 T3 DK2731650 T3 DK 2731650T3
Authority
DK
Denmark
Prior art keywords
piston rod
drive mechanism
cartridge
exendin
stop
Prior art date
Application number
DK12733747.5T
Other languages
English (en)
Inventor
Michael Jugl
Günther Sendatzki
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Application granted granted Critical
Publication of DK2731650T3 publication Critical patent/DK2731650T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M5/31513—Piston constructions to improve sealing or sliding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525—Dosing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403—Ampoule inserted into the ampoule holder
    • A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A61M5/31505—Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
    • A61M2005/31506—Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit formed as a single piece, e.g. moulded
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A61M5/31505—Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Claims (11)

1. Drivmekanisme til en lægemiddelfremføringsanordning, der omfatter: - en stempelstang (44; 70), der udgår i en aksial retning (34, 36) til operabel kobling med et stempel (28) på en patron (26), hvilken stempelstang (44; 60; 70) er indrettet til at udøve et distalt rettet tryk på stemplet (28) til udstødning af et væskeformigt medikament fra patronen (26), - en huskomponent (20) til at rumme stempelstangen (44; 60; 70), som har en styredel (40), der udgår i et lateralt plan og er i indgreb med stempelstangen (44; 60; 70) til styring af denne i aksial retning i forhold til huskomponenten (20), hvor styredelen (40) og stempelstangen (44; 60; 70) er i gevindindgreb, og - mindst én aktiveringlås (48; 52; 62; 72) til at gå i indgreb med stempelstangen (44; 60; 70) til hindring af en proksimalt rettet bevægelse af stempelstangen (44; 60; 70) i forhold til huskomponenten (20), der er kendetegnet ved, at stempelstangen (44; 60; 70) omfatter mindst én radialt indadgående forsænkning (48; 62; 72) til at gå i indgreb med mindst ét radialt indadgående stopelement (52) på aktueringslåsen, og - hvor styredelen (40) omfatter flere af stopelementerne (52), der er anbragt omkring omkredsen af stempelstangen (44; 60; 70) .
2. Drivmekanisme ifølge krav 1, hvor aktiveringslåsen omfatter mindst ét distalt og radialt indadgående stopelement (52) til at gå i indgreb med en forsænket struktur (48; 62; 72) på stempelstangen (44; 60; 70).
3. Drivmekanisme ifølge et hvilket som helst af ovennævnte krav, hvor det mindst ene stopelement (52) omfatter et elastisk deformerbart fjederelement.
4. Drivmekanisme ifølge krav 1 til 3, hvor stempelstangen (44) omfatter et ydre gevind (46) til at samvirke med et indre gevind (42) på styredelen (40) og yderligere omfatter adskillige furer (48), der strækker sig langs omkredsen af stempelstangen (44) og har en fureafstand, der adskiller sig fra fureafstanden på det ydre gevind (46).
5. Drivmekanisme ifølge krav 4, hvor furerne (48) udgår i det væsentlige vinkelret på forlængelsen af stempelstangen (44) .
6. Drivmekanisme ifølge krav 4 eller 5, hvor flere stopelementer (52) er anbragt langs omkredsen af en distal ende af det indre gevind (42) på styredelen (40) og strækker sig i distal retning (34) radialt indad.
7. Drivmekanisme ifølge krav 4 til 6, hvor stopelementerne (52) er formet som en integreret del af styredelen (40).
8. Drivmekanisme ifølge et hvilket som helst af ovennævnte krav, hvor forsænkningerne (62) omfatter en radialt indadgående stopflade (64; 74, 76) til at gå i indgreb med en lateral sidekant (56) af stopelementet (52).
9. Drivmekanisme ifølge et hvilket som helst af ovennævnte krav, hvor stopelementet (52) går i indgreb med stempelstangen (44; 70) med en lavere sidekant (54), der vender i distal retning (34).
10. Lægemiddelfremføringsanordning til indstilling og dispensering af en dosis af et medikament, der omfatter: - en drivmekanisme ifølge et hvilket som helst af ovennævnte krav og - en patronholder (30) til at rumme en patron (26), der er fyldt med et medikament, der skal dispenseres.
11. Lægemiddelfremføringsanordning ifølge krav 10, der omfatter en patron (26), der er mindst delvist fyldt med et medikament.
DK12733747.5T 2011-07-14 2012-07-12 Drivmekanisme til en lægemiddelfremføringsanordning DK2731650T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11173935 2011-07-14
PCT/EP2012/063636 WO2013007769A1 (en) 2011-07-14 2012-07-12 Drive mechanism of a drug delivery device

Publications (1)

Publication Number Publication Date
DK2731650T3 true DK2731650T3 (da) 2016-01-18

Family

ID=45531614

Family Applications (1)

Application Number Title Priority Date Filing Date
DK12733747.5T DK2731650T3 (da) 2011-07-14 2012-07-12 Drivmekanisme til en lægemiddelfremføringsanordning

Country Status (6)

Country Link
US (1) US9364616B2 (da)
EP (1) EP2731650B1 (da)
JP (1) JP6073311B2 (da)
CA (1) CA2840943A1 (da)
DK (1) DK2731650T3 (da)
WO (1) WO2013007769A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH707217A2 (de) 2014-02-26 2014-04-30 Tecpharma Licensing Ag Injektionsvorrichtung zur Verabreichung eines fluiden Produkts.
WO2017045960A1 (en) * 2015-09-18 2017-03-23 Sanofi-Aventis Deutschland Gmbh Drug delivery device

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8713810D0 (en) * 1987-06-12 1987-07-15 Hypoguard Uk Ltd Measured dose dispensing device
US4973318A (en) * 1988-02-10 1990-11-27 D.C.P. Af 1988 A/S Disposable syringe
US5578015A (en) * 1989-09-18 1996-11-26 Robb Pascal Patent Limited Safety syringe incorporating automatic needle holder release
US5545147A (en) * 1992-10-20 1996-08-13 Eli Lilly And Company Anti-backup improvement for hypodermic syringes
US6086568A (en) * 1999-10-15 2000-07-11 Becton Dickinson And Company Syringe plunger rod for retracting needle syringe
US7678084B2 (en) * 2002-03-18 2010-03-16 Eli Lilly And Company Medication dispensing apparatus with gear set for mechanical advantage
EP1663354A1 (en) 2003-09-03 2006-06-07 Novo Nordisk A/S Threaded rod and nut assembly
WO2006045525A1 (en) * 2004-10-21 2006-05-04 Novo Nordisk A/S Injection device with a processor for collecting ejection information
US7988675B2 (en) * 2005-12-08 2011-08-02 West Pharmaceutical Services Of Delaware, Inc. Automatic injection and retraction devices for use with pre-filled syringe cartridges
US7846135B2 (en) * 2006-02-24 2010-12-07 Midland Medical Holding LLC Retractable needle syringe with needle trap
CN101594896A (zh) * 2006-09-15 2009-12-02 特克法马许可公司 带有低损耗驱动器的注射仪器
US8647309B2 (en) * 2008-05-02 2014-02-11 Sanofi-Aventis Deutschland Gmbh Medication delivery device
WO2009146996A1 (en) 2008-06-05 2009-12-10 Shl Group Ab Pressure relieve mechanism for a medical delivery device
ES2648867T3 (es) * 2008-12-04 2018-01-08 Sanofi-Aventis Deutschland Gmbh Dispositivo de inyección con medios de retención para impedir movimientos no intencionados de un vástago de pistón
DK2451508T3 (da) * 2009-07-08 2014-02-10 Novo Nordisk As Frostbeskyttet injektionsanordning
US10232122B2 (en) 2009-09-07 2019-03-19 Sanofi-Aventis Deutschland Gmbh Drive mechanism for drug delivery device
US8986259B2 (en) * 2010-03-31 2015-03-24 Sanofi-Aventis Deutschland Gmbh Piston rod assembly for a drug delivery device

Also Published As

Publication number Publication date
EP2731650B1 (en) 2015-10-21
CA2840943A1 (en) 2013-01-17
JP6073311B2 (ja) 2017-02-01
US20140142516A1 (en) 2014-05-22
JP2014524803A (ja) 2014-09-25
WO2013007769A1 (en) 2013-01-17
US9364616B2 (en) 2016-06-14
EP2731650A1 (en) 2014-05-21

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