DK251481A - FLUORO-SUBSTITUTED PROSTAGLANDINES AND PROSTACYCLINES - Google Patents
FLUORO-SUBSTITUTED PROSTAGLANDINES AND PROSTACYCLINESInfo
- Publication number
- DK251481A DK251481A DK251481A DK251481A DK251481A DK 251481 A DK251481 A DK 251481A DK 251481 A DK251481 A DK 251481A DK 251481 A DK251481 A DK 251481A DK 251481 A DK251481 A DK 251481A
- Authority
- DK
- Denmark
- Prior art keywords
- prostacyclines
- prostaglandines
- fluoro
- substituted
- substituted prostaglandines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/62—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C35/48—Halogenated derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5407—Acyclic saturated phosphonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/09—Geometrical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8339879A | 1979-10-10 | 1979-10-10 | |
US10852579A | 1979-12-31 | 1979-12-31 | |
PCT/US1980/001292 WO1981001002A1 (en) | 1979-10-10 | 1980-10-02 | Fluoro-substituted prostaglandins and prostacyclins |
Publications (1)
Publication Number | Publication Date |
---|---|
DK251481A true DK251481A (en) | 1981-06-09 |
Family
ID=26769247
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK251481A DK251481A (en) | 1979-10-10 | 1981-06-09 | FLUORO-SUBSTITUTED PROSTAGLANDINES AND PROSTACYCLINES |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0037422A4 (en) |
JP (1) | JPS56501319A (en) |
DK (1) | DK251481A (en) |
IT (1) | IT1132991B (en) |
WO (1) | WO1981001002A1 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3176313D1 (en) * | 1980-12-09 | 1987-08-20 | Teijin Ltd | Novel halogenated prostacyclins, process for the production thereof, and pharmaceutical use thereof |
CH648556A5 (en) * | 1981-03-11 | 1985-03-29 | Hoffmann La Roche | FLUORPROSTACYCLINE. |
NZ200210A (en) * | 1981-04-02 | 1985-10-11 | Searle & Co | Prostacyclin pgi2 derivatives and pharmaceutical compositions |
US4579958A (en) * | 1983-12-23 | 1986-04-01 | G. D. Searle & Co. | 5-fluoro-3-oxa-6,7-didehydro-PGI1 compounds |
US4616034A (en) * | 1985-02-28 | 1986-10-07 | G. D. Searle & Co. | 15(R)-5-fluoroprostacyclins, pharmaceutical compositions and anti-thrombotic method of use thereof |
JPH01102059A (en) * | 1987-10-16 | 1989-04-19 | Asahi Glass Co Ltd | 6-fluoroprostaglandin derivative |
US5198827A (en) * | 1991-05-23 | 1993-03-30 | Hughes Aircraft Company | Dual reflector scanning antenna system |
DE69502517T2 (en) * | 1994-02-17 | 1998-10-01 | Asahi Glass Co Ltd | Difluoroprostacyclins, intermediates and processes for their preparation |
CN104755469B (en) | 2012-10-26 | 2018-04-10 | 旭硝子株式会社 | The manufacture method of difluoro ester compounds |
-
1980
- 1980-10-02 JP JP50258880A patent/JPS56501319A/ja active Pending
- 1980-10-02 WO PCT/US1980/001292 patent/WO1981001002A1/en not_active Application Discontinuation
- 1980-10-13 IT IT25285/80A patent/IT1132991B/en active
-
1981
- 1981-04-21 EP EP19800902203 patent/EP0037422A4/en not_active Withdrawn
- 1981-06-09 DK DK251481A patent/DK251481A/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IT1132991B (en) | 1986-07-09 |
WO1981001002A1 (en) | 1981-04-16 |
EP0037422A4 (en) | 1982-01-26 |
IT8025285A0 (en) | 1980-10-13 |
EP0037422A1 (en) | 1981-10-14 |
JPS56501319A (en) | 1981-09-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO803330L (en) | ELECTROLYSOUS AND PROCEDURE FOR ELECTROLIZATION | |
DK197178A (en) | CONNECTION AND MEANS | |
TR21804A (en) | ZIRAI UERELER AND IZOUERELER | |
DK92676A (en) | GRAIN-BREAKING ANTI-MATERIALS AND THEIR USE | |
DK401583A (en) | PARENCYMAL CELL-CELLULOSE AND RELATED MATERIALS | |
DK11877A (en) | ANTHRA-CYCLING LYCOSIDES AND PROCEDURE | |
DK234178A (en) | PRINT-SENSITIVE RECORDING AND COPYING MATERIAL | |
DK421480A (en) | METHODS AND FIREPLACEMENT PLACES | |
NO149596C (en) | SOUND AND SWITCH-INSULATING PARTS | |
NO153338C (en) | Particulate bleach and its use. | |
IT1156704B (en) | PROCEDURE AND CRYO-DRYING APPARATUS THROUGH HYPERFREQUENCES | |
DK251481A (en) | FLUORO-SUBSTITUTED PROSTAGLANDINES AND PROSTACYCLINES | |
DK465880A (en) | TEXTILE-SOFT AND ANTISTATIC RELATIONS | |
IT1193576B (en) | 17ALPHA-ACYLOXY-5BETA-CORTICOID AND 17ALPHA-ACYLOXY-5ALPHA-CORTICOID | |
DK91777A (en) | SEPARATE FIXING PART FOR INTRAVENOSE CANNULES AND CATHETRES | |
DK355378A (en) | 4-HYDROXY-2-BENZIMIDAZONE DERIVATIVES AND PROCEDURES | |
DK12580A (en) | ANTIBIOTICS C-19393S2 AND H2 | |
DK151570C (en) | DESCRIPTION OF SULFURES AND DESCRIPTION | |
IT1142142B (en) | 5ALFA-ANDROSTAN-17BETA-CARBOXYLATE AND 5BETA-ANDROSTAN-17BETA-CARBOXYLATE | |
DK426880A (en) | HARZBURGIT AND PROCEDURES FOR PRODUCING THEREOF | |
IT1192305B (en) | HARVEST-GRAIN-GRINDER AND SIMILAR | |
TR19891A (en) | INSECTIVE AND AKARISID SUBSTANCES | |
BR7702936A (en) | MECHANISM AND JETOR | |
TR20553A (en) | CAYDA OR CAYLA TIGILI BREEDING | |
DK571277A (en) | HAEGTE FOR LINNINGS AND THE LIKE |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |