DK2430007T3 - Fremgangsmåde for kemisk syntese af diaminophenothiazinium forbindelser ved anvendelse af persulfat oxidanter - Google Patents
Fremgangsmåde for kemisk syntese af diaminophenothiazinium forbindelser ved anvendelse af persulfat oxidanterInfo
- Publication number
- DK2430007T3 DK2430007T3 DK10718268.5T DK10718268T DK2430007T3 DK 2430007 T3 DK2430007 T3 DK 2430007T3 DK 10718268 T DK10718268 T DK 10718268T DK 2430007 T3 DK2430007 T3 DK 2430007T3
- Authority
- DK
- Denmark
- Prior art keywords
- chemical synthesis
- diaminophenothiazinium compounds
- oxidants
- persulfate
- persulfate oxidants
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/18—[b, e]-condensed with two six-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
- C07C381/02—Thiosulfates
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17744609P | 2009-05-12 | 2009-05-12 | |
| PCT/GB2010/000927 WO2010130977A1 (en) | 2009-05-12 | 2010-05-11 | Methods of chemical synthesis of diaminophenothiazinium compounds involving the use of persulfate oxidants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2430007T3 true DK2430007T3 (da) | 2014-05-12 |
Family
ID=42238536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK10718268.5T DK2430007T3 (da) | 2009-05-12 | 2010-05-11 | Fremgangsmåde for kemisk syntese af diaminophenothiazinium forbindelser ved anvendelse af persulfat oxidanter |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8691979B2 (da) |
| EP (1) | EP2430007B1 (da) |
| DK (1) | DK2430007T3 (da) |
| ES (1) | ES2457227T3 (da) |
| PL (1) | PL2430007T3 (da) |
| PT (1) | PT2430007E (da) |
| SI (1) | SI2430007T1 (da) |
| WO (1) | WO2010130977A1 (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102634015B (zh) * | 2012-05-04 | 2013-06-19 | 中南大学 | 一种聚间苯二胺纳米粒子合成方法 |
| GB201317702D0 (en) | 2013-10-07 | 2013-11-20 | Wista Lab Ltd | Methods of chemical synthesis of diaminophenothiazinium compounds including methylthioninium chloride (MTC) |
| GB201621817D0 (en) | 2016-12-21 | 2017-02-01 | Wista Lab Ltd | Methods of chemical synthesis |
| EP3375777A1 (en) | 2017-03-15 | 2018-09-19 | MIKROCHEM spol. s.r.o. | Method for preparation of 3,7-bis-(dimethylamino)-phenothiazin-5-ium chloride or bromide |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1886C (de) | 1877-12-15 | 1877-12-15 | Basf Ag | Verfahren zur darstellung blauer farbstoffe aus dimethylanilin und anderen tertiaeren aromatischen monaminen |
| US5344928A (en) | 1991-04-26 | 1994-09-06 | Takeda Chemical Industries, Ltd. | Phenothiazine derivatives, their production and use |
| GB9506197D0 (en) | 1995-03-27 | 1995-05-17 | Hoffmann La Roche | Inhibition of tau-tau association. |
| GB0101049D0 (en) | 2001-01-15 | 2001-02-28 | Univ Aberdeen | Materials and methods relating to protein aggregation in neurodegenerative disease |
| GB0106953D0 (en) | 2001-03-20 | 2001-05-09 | Univ Aberdeen | Neufofibrillary labels |
| DK1799662T3 (da) | 2004-09-23 | 2013-07-15 | Wista Lab Ltd | Fremgangsmåder til kemisk syntese og oprensning af diaminophenothiaziniumforbindelser, herunder methylthioniniumchlorid (MTC) |
-
2010
- 2010-05-11 PT PT107182685T patent/PT2430007E/pt unknown
- 2010-05-11 US US13/318,907 patent/US8691979B2/en active Active
- 2010-05-11 ES ES10718268.5T patent/ES2457227T3/es active Active
- 2010-05-11 DK DK10718268.5T patent/DK2430007T3/da active
- 2010-05-11 EP EP10718268.5A patent/EP2430007B1/en active Active
- 2010-05-11 PL PL10718268T patent/PL2430007T3/pl unknown
- 2010-05-11 SI SI201030572T patent/SI2430007T1/sl unknown
- 2010-05-11 WO PCT/GB2010/000927 patent/WO2010130977A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| EP2430007B1 (en) | 2014-02-12 |
| PT2430007E (pt) | 2014-04-14 |
| US20120058995A1 (en) | 2012-03-08 |
| PL2430007T3 (pl) | 2014-07-31 |
| US8691979B2 (en) | 2014-04-08 |
| ES2457227T3 (es) | 2014-04-25 |
| SI2430007T1 (sl) | 2014-05-30 |
| WO2010130977A1 (en) | 2010-11-18 |
| EP2430007A1 (en) | 2012-03-21 |
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| DK2430007T3 (da) | Fremgangsmåde for kemisk syntese af diaminophenothiazinium forbindelser ved anvendelse af persulfat oxidanter |